Observational Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Pediatr. Jun 9, 2023; 12(3): 125-132
Published online Jun 9, 2023. doi: 10.5409/wjcp.v12.i3.125
Psychiatric disorders and caregiver burden in children with transfusion dependent β-thalassaemia and their caregivers
Samiksha Sahu, Amit Agrawal, Jyotsna Shrivastava, Sudhir Tonk
Samiksha Sahu, Department of Psychiatry, Gandhi Medical College, Bhopal 462030, Madhya Pradesh, India
Amit Agrawal, Jyotsna Shrivastava, Sudhir Tonk, Department of Pediatrics, Gandhi Medical College, Bhopal 462030, Madhya Pradesh, India
Author contributions: Sahu S participated in the data collection, and interpretation of data and executed the study; Tonk S participated in the data collection, and interpretation of data; Agrawal A participated in the data analysis and manuscript writing; Srivastava J participated in drafting and editing the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Ethics committee of Gandhi Medical College.
Informed consent statement: All study participants, or their legal guardians, provided informed written consent before study enrolment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—a checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—a checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Amit Agrawal, MD, Associate Professor, Department of Pediatrics, Gandhi Medical College, Hamidia Hospital Campus, Bhopal 462030, Madhya Pradesh, India. agrawaldramit@yahoo.co.in
Received: January 28, 2023
Peer-review started: January 28, 2023
First decision: February 20, 2023
Revised: January 31, 2023
Accepted: March 31, 2023
Article in press: March 31, 2023
Published online: June 9, 2023
Processing time: 130 Days and 16.5 Hours
Core Tip

Core Tip: Thalassemia is a major public health problem because of its high prevalence ranging from 2%-5%. Like other chronic illnesses, patients with thalassemia are vulnerable to emotional and behavioral problems making them susceptible to a myriad of psychiatric disorders. The emotional and psychological problems faced by thalassaemic children and their caregivers are often overlooked resulting in increased suffering and poor outcome. In this observational, cross-sectional study we analyze 46 children with transfusion-dependent Thalassemia for the presence of psychiatric disorders along with the caregiver burden experienced by the caregivers of these children.