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World J Clin Pediatr. Jan 9, 2022; 11(1): 27-37
Published online Jan 9, 2022. doi: 10.5409/wjcp.v11.i1.27
Hereditary pancreatitis: An updated review in pediatrics
Arvind Vasant Panchoo, Grant H VanNess, Edgardo Rivera-Rivera, Trevor J Laborda
Arvind Vasant Panchoo, Trevor J Laborda, Division of Gastroenterology, Hepatology and Nutrition, The Children’s Hospital of San Antonio, San Antonio, TX 78207, United States
Arvind Vasant Panchoo, Trevor J Laborda, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, United States
Grant H VanNess, Faculty of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, United States
Edgardo Rivera-Rivera, Department of Pediatric Gastroenterology, Parkview Health, Fort Wayne, IN 46845, United States
Author contributions: Panchoo AV performed data acquisition, drafting the manuscript and preparation of the figures and tables; VanNess GH, Rivera-Rivera E and Laborda TJ provided input in writing the paper; Panchoo AV, VanNess GH, Rivera-Rivera E and Laborda TJ performed critical revision and final approval of the submitted manuscript.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Arvind Vasant Panchoo, MD, Doctor, Pediatric Gastroenterology Fellow, Division of Gastroenterology, Hepatology and Nutrition, The Children’s Hospital of San Antonio, No. 333 Santa Rosa Street, CCF F3725, San Antonio, TX 78207, United States. arvindpanchoo001@gmail.com
Received: March 31, 2021
Peer-review started: March 31, 2021
First decision: July 27, 2021
Revised: August 8, 2021
Accepted: November 22, 2021
Article in press: November 22, 2021
Published online: January 9, 2022
Processing time: 282 Days and 5 Hours
Core Tip

Core Tip: Herediatry Pancreatitis is associated with the inheritance of pathologic genetic mutations. Recent work in pediatrics has isolated genetic variants responsible for early onset and rapidly progressive disease. Early identification of at risk patients and timely referral to appropriate tertiary centers has the ability to limit health care cost and substantial sequelae of this aggressive disease continuum. Further research is warranted to better define preventative management strategies.