Puvabanditsin S, Mehta R, Palomares K, Gengel N, Silva CFD, Roychowdhury S, Gupta G, Kashyap A, Sorrentino D. Vein of Galen malformation in a neonate: A case report and review of endovascular management. World J Clin Pediatr 2017; 6(1): 103-109 [PMID: 28224101 DOI: 10.5409/wjcp.v6.i1.103]
Corresponding Author of This Article
Surasak Puvabanditsin, MD, Department of Pediatrics, Rutgers-RWJ Medical School, 1 Robert Wood Johnson Place, New Brunswick, NJ 08903, United States. surasak1@aol.com
Research Domain of This Article
Pediatrics
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Pediatr. Feb 8, 2017; 6(1): 103-109 Published online Feb 8, 2017. doi: 10.5409/wjcp.v6.i1.103
Vein of Galen malformation in a neonate: A case report and review of endovascular management
Surasak Puvabanditsin, Rajeev Mehta, Kristy Palomares, Natalie Gengel, Christina Ferrucci-Da Silva, Sudipta Roychowdhury, Gaurav Gupta, Arun Kashyap, David Sorrentino
Surasak Puvabanditsin, Rajeev Mehta, Natalie Gengel, Christina Ferrucci-Da Silva, Arun Kashyap, David Sorrentino, Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903, United States
Kristy Palomares, Department of Obstetrics and Gynecology, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903, United States
Sudipta Roychowdhury, Gaurav Gupta, Department of Neurosurgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903, United States
Author contributions: All authors contributed to the acquisition of data, writing, and revision of this manuscript.
Institutional review board statement: This case report was exempt from the Institutional Review Board standards at Rutgers Robert Wood Johnson Medical School.
Conflict-of-interest statement: The authors declare no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Surasak Puvabanditsin, MD, Department of Pediatrics, Rutgers-RWJ Medical School, 1 Robert Wood Johnson Place, New Brunswick, NJ 08903, United States. surasak1@aol.com
Telephone: +1-732-2355691 Fax: +1-732-2355668
Received: May 2, 2016 Peer-review started: May 3, 2016 First decision: July 25, 2016 Revised: October 12, 2016 Accepted: November 1, 2016 Article in press: November 2, 2016 Published online: February 8, 2017 Processing time: 277 Days and 7.4 Hours
Abstract
Vein of Galen malformation (VOGM) is a rare congenital vascular malformation caused by the maldevelopment of its embryonic precursor, the median prosencephalic vein of Markowski. VOGM results in neonatal morbidity and mortality, and premature delivery does not improve the outcome. We report a term female neonate in whom a vein of Galen malformation was diagnosed prenatally at 37 wk of gestation during a growth ultrasound and confirmed by fetal magnetic resonance imaging. Signs of cardiac decompensation were evident in the fetus. Multiple interventional radiology embolizations of the feeding vessels were performed successfully on days 7, 10, 12, 14 and 19. A review of the literature on the endovascular management of neonates with these malformations is presented herein.
Core tip: Vein of Galen malformation (VOGM) is a rare vascular anomaly that may present in the fetus or newborn, and may cause congestive heart failure. Historically, the management of VOGMs was neurosurgical, but outcomes were uniformly poor. Since the introduction of endovascular interventional techniques, the likelihood of a successful treatment is much greater and a cure is potentially achievable. We report herein a term female neonate with a VOGM that was sucessfully treated with multiple endovascular embolizations, and also present a review of the literature on the endovascular management of neonates.
