Nagoba BS, Dhotre SV, Gavkare AM, Mumbre SS, Dhotre PS. Understanding serum inflammatory markers in pediatric Mycoplasma pneumoniae pneumonia. World J Clin Pediatr 2024; 13(4): 98809 [DOI: 10.5409/wjcp.v13.i4.98809]
Corresponding Author of This Article
Basavraj S Nagoba, PhD, Professor, Department of Microbiology, Maharashtra Institute of Medical Sciences and Research (Medical College), Vishwanathpuram, Ambajogai road, Latur 413531, India. dr_bsnagoba@yahoo.com
Research Domain of This Article
Infectious Diseases
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Pediatr. Dec 9, 2024; 13(4): 98809 Published online Dec 9, 2024. doi: 10.5409/wjcp.v13.i4.98809
Understanding serum inflammatory markers in pediatric Mycoplasma pneumoniae pneumonia
Basavraj S Nagoba, Shree V Dhotre, Ajay M Gavkare, Sachin S Mumbre, Pradnya S Dhotre
Basavraj S Nagoba, Department of Microbiology, Maharashtra Institute of Medical Sciences and Research (Medical College), Latur 413531, India
Shree V Dhotre, Department of Microbiology, Ashwini Rural Medical College, Solapur 413001, India
Ajay M Gavkare, Department of Physiology, Maharashtra Institute of Medical Sciences and Research (Medical College), Latur 413531, India
Sachin S Mumbre, Department of Community Medicine, Ashwini Rural Medical College, Solapur 413006, India
Pradnya S Dhotre, Department of Biochemistry, Ashwini Rural Medical College, Solapur 413001, India
Co-first authors: Basavraj S Nagoba and Shree V Dhotre.
Author contributions: Nagoba BS designed the overall concept and outline of the manuscript; Dhotre SV, Gavkare AM, Mumbre SS, and Dhotre PS contributed to the discussion and design of the manuscript; Nagoba BS, Dhotre SV and Gavkare AM contributed to the writing, and editing the manuscript and review of literature; all of the authors read and approved the final version of the manuscript to be published.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Basavraj S Nagoba, PhD, Professor, Department of Microbiology, Maharashtra Institute of Medical Sciences and Research (Medical College), Vishwanathpuram, Ambajogai road, Latur 413531, India. dr_bsnagoba@yahoo.com
Received: July 6, 2024 Revised: September 9, 2024 Accepted: September 19, 2024 Published online: December 9, 2024 Processing time: 116 Days and 4.3 Hours
Abstract
This editorial reflects on the research, which investigates the potential of serum markers to predict the severity of Mycoplasma pneumoniae infections. Mycoplasma pneumoniae pneumonia (MPP) is a prevalent cause of respiratory infections in children, often leading to significant morbidity. Predicting the severity of MPP can significantly enhance patient management and outcomes. This editorial reviews the role of specific laboratory markers: (1) Lactate dehydrogenase; (2) Interleukin (IL)-6; (3) IL-10; (4) Tumor necrosis factor-α; and (5) D-dimer in predicting the severity of MPP in pediatric patients. Elevated levels of these markers are strongly associated with severe cases of MPP, providing clinicians with valuable tools for early diagnosis and targeted intervention.
Core Tip: This editorial underscores the significance of laboratory markers in predicting the severity of Mycoplasma pneumoniae pneumonia (MPP) in children. Elevated levels of lactate dehydrogenase, interleukin (IL)-6, IL-10, tumor necrosis factor-α, and D-dimer are identified as critical indicators of severe MPP. Utilizing these markers can aid in the early identification of severe cases, facilitating timely intervention and improving clinical outcomes in pediatric patients.
