Gupta A, Choudhary N, Gupta N. Prediabetes in children and adolescents: A ticking bomb! World J Clin Pediatr 2024; 13(2): 92127 [PMID: 38947990 DOI: 10.5409/wjcp.v13.i2.92127]
Corresponding Author of This Article
Nishkarsh Gupta, MD, Professor, Department of Onco-Anesthesiology and Palliative Medicine, All India Institute of Medical Science, Room No. 139 FF IRCH AIIMS, New Delhi 110029, India. drnishkarsh@rediffmail.com
Research Domain of This Article
Pediatrics
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Pediatr. Jun 9, 2024; 13(2): 92127 Published online Jun 9, 2024. doi: 10.5409/wjcp.v13.i2.92127
Prediabetes in children and adolescents: A ticking bomb!
Anju Gupta, Nitin Choudhary, Nishkarsh Gupta
Anju Gupta, Nitin Choudhary, Department of Anesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Science, New Delhi 110076, India
Nishkarsh Gupta, Department of Onco-Anesthesiology and Palliative Medicine, All India Institute of Medical Science, New Delhi 110029, India
Author contributions: Gupta A and Gupta N designed the study; Choudhary N and Gupta A wrote the manuscript; All authors have read and approve the final manuscript.
Conflict-of-interest statement: The authors declare no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Nishkarsh Gupta, MD, Professor, Department of Onco-Anesthesiology and Palliative Medicine, All India Institute of Medical Science, Room No. 139 FF IRCH AIIMS, New Delhi 110029, India. drnishkarsh@rediffmail.com
Received: January 21, 2024 Revised: February 12, 2024 Accepted: April 25, 2024 Published online: June 9, 2024 Processing time: 137 Days and 21.1 Hours
Abstract
Prediabetes in children and adolescents is on the rise which has drawn significant attention over the past decade. It is an early warning sign of the underlying pathophysiological changes which in due course of time might compound into type II diabetes mellitus. The incidence of prediabetes in adolescents ranges from 4%-23% which is alarmingly high and requires active intervention from the system. We have discussed early identification of high-risk patients, prompt screening and active intervention to manage this growing problem.
Core Tip: Prediabetes is an early warning sign of an underlying pathophysiological change in glucose metabolism which in the due course of time might advance to type II diabetes mellitus. There has been a recent global upsurge in prediabetes in children and adolescents. Notwithstanding, there is still a dearth of sufficient literature regarding this very pertinent issue. Prediabetes status must be identified at the earliest to prevent further medical complications. American Diabetes Association and the International Society for Paediatric and Adolescent Diabetes recommend the screening of high-risk children for developing prediabetes. At present, the possible ways of managing this crisis are the prevention of childhood obesity, early identification and screening of high-risk patients, and active intervention.