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Bhandari N, Cuffey JM, Miao R, Zilberman D. Heterogeneity of the Association Between Obesity and COVID-19 Mortality and the Roles of Policy Interventions: U.S. National-Level Analysis. AJPM FOCUS 2025; 4:100312. [PMID: 39967684 PMCID: PMC11834079 DOI: 10.1016/j.focus.2024.100312] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Indexed: 02/20/2025]
Abstract
This article examines the heterogeneity of the association between obesity and COVID-19 mortality across various dimensions, including COVID-19 vaccination rates, mask mandates, gathering restrictions, and household income. Using multivariate regression analysis on U.S. county-level data over 2020-2021, the authors found that county-level adult obesity rates were positively associated with COVID-19 death rates. The results suggest that on average, a 10-percentage-point decrease in adult obesity rate is associated with a decrease in COVID-19 deaths by 4.79%-5.98% in the U.S. Considering that the average adult obesity rate in the U.S. is higher than the global average, this finding may explain why deaths due to COVID-19 were disproportionately large in the U.S. In addition, the authors found that association between obesity and the COVID-19 death rate is much more pronounced in groups with low vaccination rates, weak mask mandates, loose gathering restrictions, or low household incomes, indicating the importance of COVID-19 response policies and income to people with obesity facing a pandemic. The study results contribute to policy discussions surrounding preparation for COVID-19-like pandemics. Food policies and health promotion strategies that encourage physical well-being to reduce obesity prevalence may help reduce mortality in future pandemics.
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Affiliation(s)
- Nabin Bhandari
- Department of Agricultural Economics & Rural Sociology, Auburn University, Auburn, Alabama
| | - Joel M. Cuffey
- Department of Agricultural Economics & Rural Sociology, Auburn University, Auburn, Alabama
| | - Ruiqing Miao
- Department of Agricultural Economics & Rural Sociology, Auburn University, Auburn, Alabama
| | - David Zilberman
- Department of Agricultural and Resource Economics, Rausser College of Natural Resources, University of California, Berkeley, Berkeley, California
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Mottalib MM, Phan TLT, Bramante CT, Chute CG, Pyles LA, Beheshti R, N3C. Impact of COVID-19 Diagnosis on Weight Trajectories of Children in the US National COVID Cohort Collaborative. Child Obes 2025; 21:380-391. [PMID: 39761108 DOI: 10.1089/chi.2024.0256] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 01/15/2025]
Abstract
Background: The COVID-19 pandemic has exacerbated the obesity epidemic, with both adults and children demonstrating rapid weight gain during the pandemic. However, the impact of having a COVID-19 diagnosis on this trend is not known. Methods: Using longitudinal data from January 2019 to June 2023 collected by the US National Institute for Health's National COVID Cohort Collaborative (N3C), children (age 2-18 years) with positive COVID-19 test results {n = 11,474, 53% male, mean [standard deviation (SD)] age 5.57 [±3.29] years, 54% White, mean [SD] 5.2 [±2.9] BMI observations per participant} were matched with COVID-19-negative children with identical demographic characteristics and similar observation window. We compared BMI percentile trajectories between the COVID-19-positive and COVID-19-negative cohorts, with further evaluation performed on COVID-19-positive patients stratified by hospitalization status. Results: COVID-19-positive patients had a greater increase in % B M I p 95 than COVID-19-negative patients (average increase of 2.34 (±7.73) compared to 1.46 (±6.09), p < 0.0005). COVID-19-positive patients gained more weight after their diagnosis of COVID-19 than before. Nonhospitalized children gained more weight than hospitalized children [average increase in % B M I p 95 of 2.38 (±7.65) compared to 1.87 (±8.54)]. Mixed-effect regression analyses demonstrated that these associations remained even after adjusting for time, demographics, and baseline % B M I p 95 . Conclusions: Having a COVID-19 diagnosis was associated with more rapid weight gain, especially after diagnosis and early in the pandemic. Future research should explore the reasons for this association and the implications for future health emergencies.
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Affiliation(s)
| | | | | | | | - Lee A Pyles
- West Virginia University, Morgantown, West Virginia, USA
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Carbone F, Després JP, Ioannidis JPA, Neeland IJ, Garruti G, Busetto L, Liberale L, Ministrini S, Vilahur G, Schindler TH, Macedo MP, Di Ciaula A, Krawczyk M, Geier A, Baffy G, Faienza MF, Farella I, Santoro N, Frühbeck G, Yárnoz-Esquiroz P, Gómez-Ambrosi J, Chávez-Manzanera E, Vázquez-Velázquez V, Oppert JM, Kiortsis DN, Sbraccia P, Zoccali C, Portincasa P, Montecucco F. Bridging the gap in obesity research: A consensus statement from the European Society for Clinical Investigation. Eur J Clin Invest 2025:e70059. [PMID: 40371883 DOI: 10.1111/eci.70059] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/09/2025] [Accepted: 04/12/2025] [Indexed: 05/16/2025]
Abstract
BACKGROUND Most forms of obesity are associated with chronic diseases that remain a global public health challenge. AIMS Despite significant advancements in understanding its pathophysiology, effective management of obesity is hindered by the persistence of knowledge gaps in epidemiology, phenotypic heterogeneity and policy implementation. MATERIALS AND METHODS This consensus statement by the European Society for Clinical Investigation identifies eight critical areas requiring urgent attention. Key gaps include insufficient long-term data on obesity trends, the inadequacy of body mass index (BMI) as a sole diagnostic measure, and insufficient recognition of phenotypic diversity in obesity-related cardiometabolic risks. Moreover, the socio-economic drivers of obesity and its transition across phenotypes remain poorly understood. RESULTS The syndemic nature of obesity, exacerbated by globalization and environmental changes, necessitates a holistic approach integrating global frameworks and community-level interventions. This statement advocates for leveraging emerging technologies, such as artificial intelligence, to refine predictive models and address phenotypic variability. It underscores the importance of collaborative efforts among scientists, policymakers, and stakeholders to create tailored interventions and enduring policies. DISCUSSION The consensus highlights the need for harmonizing anthropometric and biochemical markers, fostering inclusive public health narratives and combating stigma associated with obesity. By addressing these gaps, this initiative aims to advance research, improve prevention strategies and optimize care delivery for people living with obesity. CONCLUSION This collaborative effort marks a decisive step towards mitigating the obesity epidemic and its profound impact on global health systems. Ultimately, obesity should be considered as being largely the consequence of a socio-economic model not compatible with optimal human health.
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Affiliation(s)
- Federico Carbone
- Department of Internal Medicine, University of Genoa, Genoa, Italy
- IRCCS Ospedale Policlinico San Martino, Genoa, Genoa, Italy
| | - Jean-Pierre Després
- Institut Universitaire de Cardiologie et de Pneumologie de Québec - Université Laval, Québec, Québec, Canada
- VITAM - Centre de Recherche en santé Durable, Centre intégré Universitaire de santé et de Services Sociaux de la Capitale-Nationale, Québec, Québec, Canada
| | - John P A Ioannidis
- Department of Medicine, Stanford Cardiovascular Institute, and Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Stanford, California, USA
- Department of Epidemiology and Population Health, Stanford Cardiovascular Institute, and Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Stanford, California, USA
- Department of Biomedical Science, Stanford Cardiovascular Institute, and Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Stanford, California, USA
| | - Ian J Neeland
- Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
- Department of Cardiovascular Disease, Harrington Heart and Vascular Institute, Cleveland, Ohio, USA
| | - Gabriella Garruti
- Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari "Aldo Moro", Bari, Italy
| | - Luca Busetto
- Department of Medicine, University of Padua, Padua, Italy
| | - Luca Liberale
- Department of Internal Medicine, University of Genoa, Genoa, Italy
- IRCCS Ospedale Policlinico San Martino, Genoa, Genoa, Italy
| | - Stefano Ministrini
- Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland
- Cardiology Department, Luzerner Kantonspital, Lucerne, Switzerland
| | - Gemma Vilahur
- Research Institute, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, IIB-Sant Pau, Barcelona, Spain
- CiberCV, Institute Carlos III, Madrid, Spain
| | - Thomas H Schindler
- Washington University in St. Louis, Mallinckrodt Institute of Radiology, Division of Nuclear Medicine, Cardiovascular Medicine, Washington University School of Medicine, St. Louis, Missouri, USA
| | - Maria Paula Macedo
- APDP - Diabetes Portugal, Education and Research Center, Lisbon, Portugal
- iNOVA4Health, NOVA Medical School | Faculdade de Ciências Médicas, NMS | FCM, Universidade Nova de Lisboa, Lisbon, Portugal
| | - Agostino Di Ciaula
- Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari "Aldo Moro", Bari, Italy
| | - Marcin Krawczyk
- Department of Gastroenterology, Hepatology and Transplant Medicine, Medical Faculty, University of Duisburg-Essen, Essen, Germany
- Laboratory of Metabolic Liver Diseases, Department of General, Transplant and Liver Surgery, Centre for Preclinical Research, Medical University of Warsaw, Warsaw, Poland
| | - Andreas Geier
- Interdisciplinary Amyloidosis Center of Northern Bavaria, University Hospital of Würzburg, Würzburg, Germany
- Department of Internal Medicine II, Hepatology, University Hospital of Würzburg, Würzburg, Germany
| | - Gyorgy Baffy
- Department of Medicine, VA Boston Healthcare System, Harvard Medical School, Boston, Massachusetts, USA
| | - Maria Felicia Faienza
- Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari "Aldo Moro", Bari, Italy
| | - Ilaria Farella
- Department of Medicine and Surgery, LUM University, Casamassima, Italy
| | - Nicola Santoro
- Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
- Department of Medicine and Health Sciences, "V. Tiberio" University of Molise, Campobasso, Italy
| | - Gema Frühbeck
- Department of Endocrinology and Nutrition, Cancer Center Clínica Universidad de Navarra (CCUN), Pamplona, Spain
- IdiSNA (Instituto de Investigación en la Salud de Navarra), Pamplona, Spain
- CIBERObn (CIBER Fisiopatología de la Obesidad y Nutrición), Instituto de Salud Carlos III, Madrid, Spain
| | - Patricia Yárnoz-Esquiroz
- Department of Endocrinology and Nutrition, Cancer Center Clínica Universidad de Navarra (CCUN), Pamplona, Spain
- IdiSNA (Instituto de Investigación en la Salud de Navarra), Pamplona, Spain
- CIBERObn (CIBER Fisiopatología de la Obesidad y Nutrición), Instituto de Salud Carlos III, Madrid, Spain
| | - Javier Gómez-Ambrosi
- Department of Endocrinology and Nutrition, Cancer Center Clínica Universidad de Navarra (CCUN), Pamplona, Spain
- IdiSNA (Instituto de Investigación en la Salud de Navarra), Pamplona, Spain
- CIBERObn (CIBER Fisiopatología de la Obesidad y Nutrición), Instituto de Salud Carlos III, Madrid, Spain
| | - Emma Chávez-Manzanera
- Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico
| | | | - Jean-Michel Oppert
- Department of Nutrition, Pitié-Salpêtrière Hospital (AP-HP), Human Nutrition Research Center Ile-de-France (CRNH IdF), Sorbonne University, Paris, France
| | - Dimitrios N Kiortsis
- Atherothrombosis Research Centre, Faculty of Medicine, University of Ioannina, Ioannina, Greece
| | - Paolo Sbraccia
- Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy
| | - Carmine Zoccali
- Renal Research Institute, New York, New York, USA
- Institute of Molecular Biology and Genetics (Biogem), Ariano Irpino, Italy
- Associazione Ipertensione Nefrologia Trapianto Renale (IPNET), c/o Nefrologia, Grande Ospedale Metropolitano, Reggio Calabria, Italy
| | - Piero Portincasa
- Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari "Aldo Moro", Bari, Italy
| | - Fabrizio Montecucco
- Department of Internal Medicine, University of Genoa, Genoa, Italy
- IRCCS Ospedale Policlinico San Martino, Genoa, Genoa, Italy
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Bekaert S, Rawlings M, Shariff D, Sammut D, Cook G. New Modes of Practice: A Framework Analysis of School Nurses' Accounts of Working With Children and Young People During COVID-19. J Adv Nurs 2025; 81:2572-2585. [PMID: 39352004 PMCID: PMC11967332 DOI: 10.1111/jan.16490] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/17/2024] [Revised: 08/19/2024] [Accepted: 09/09/2024] [Indexed: 10/03/2024]
Abstract
AIMS To identify new and accelerated modes of practice used by school nurses during the COVID pandemic. To create a quick reference infographic bringing together experiential evidence on the range and considerations regarding different modes of practice for use by the school nursing community of practice. DESIGN A descriptive qualitative secondary data analysis of open-ended questions in a survey, and focus groups with school nurses. The pragmatic aim was to focus on changes in school nurse modes of practice to ensure continued engagement with children and young people, and school nurses' experience of the benefits and challenges of these modes of practice. METHODS Data were collected from 98 school nurse participants across a United Kingdom-wide survey (n78) in April to May 2022, and focus groups (n20) in June to July 2022, within the School Nursing in the Time of COVID project. Data from the seven open-ended questions in the survey and four questions from the focus group were analysed using the framework approach. RESULTS Modes of practice fell into two categories: individual assessment and support (video-calling platforms, telephone contact, virtual messaging, walk-and-talks and home visits) and group support (wellbeing approaches, social media). Considerations for these modes rooted in school nurses' experience are described. Interpretations were used to create the summarising evidence-based infographic as a quick reference resource for school nurses. CONCLUSION There was no 'one size fits all' approach. The modes used by school nurses were adopted or developed out of necessity or resource availability and in response to the specific needs of individuals or groups. The developed infographic provides a quick reference guide to deliver the expressed need for knowledge exchange within the school nursing community by participants in the original studies and can be used to inform current school nurse practice. IMPLICATIONS FOR THE PROFESSION AND/OR PATIENT CARE The developed evidence-based infographic has stand-alone value. It has the potential to raise awareness of the range of different strategies that can be used to facilitate and/or enhance engagement with children and young people, equip school nurses with knowledge to foster innovative and responsive practice and aid critical reflection in a complex post-pandemic landscape. The infographic is a unique resource and is a first step in knowledge exchange based on experiential learning. The resource will be used as the foundation for future work to develop a co-created training resource for school nurse students (undertaking the Specialist Community Public Health Nurses course) and/or continuing professional development resource for established school nurses. REPORTING METHOD This study has been conducted and reported in accordance with COREQ guidelines for qualitative research. PATIENT OR PUBLIC CONTRIBUTION A consultation group was closely involved with the planning, conduct and analysis of the original studies. This group consisted of representatives from professional organisations SAPHNA (School and Public Health Nurses Association) and the CPHVA (Community Practitioners' and Health Visitors' Association), a school nurse and a member of the public. SAPHNA have continued in their consultative role for this study and has provided content and usability feedback regarding the infographic. Early findings have been presented to the SN community of practice, and feedback invited, through presentation separately at the CPHVA and SAPHNA annual conference.
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Affiliation(s)
- Sarah Bekaert
- Faculty of Health and Life SciencesOxford Brookes UniversityOxfordUK
| | - Maisie Rawlings
- Faculty of Health and Life SciencesOxford Brookes UniversityOxfordUK
| | - Dominic Shariff
- Faculty of Health and Life SciencesOxford Brookes UniversityOxfordUK
| | - Dana Sammut
- Centre for Healthcare and CommunitiesUniversity of CoventryCoventryUK
| | - Georgia Cook
- Faculty of Health and Life SciencesOxford Brookes UniversityOxfordUK
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Englund J, Olofsson N. Effects of the COVID-19 Pandemic on Children's Body Mass Index Trajectories in Sweden. J Pediatr 2025; 280:114500. [PMID: 39938592 DOI: 10.1016/j.jpeds.2025.114500] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 11/28/2024] [Revised: 01/20/2025] [Accepted: 02/01/2025] [Indexed: 02/14/2025]
Abstract
OBJECTIVES To examine the effects of societal and public health changes during the COVID-19 pandemic in Sweden on children's body mass index (BMI) and to determine whether the effect persisted and differed between the sexes. STUDY DESIGN We used growth curve models applied to retrospective cohorts of children in preschool, grade 4, grade 7, and the first year of high school between the years 2014 and 2023. The data include information on the BMI of individuals in these grades. RESULTS The results indicate that the pandemic in Sweden was associated with a very small weight gaining effect among children, with no substantial differences between the sexes. The effect peaked approximately 2 years after the beginning of the pandemic, following which the BMI began trending back toward levels that would be expected had the pandemic not affected children's body weight. CONCLUSIONS These study findings from Sweden partially align with those of international studies, although the effect is smaller in magnitude compared with international estimates. The results of this study suggest that more liberal restrictions, compared with stricter ones, are associated with a smaller excess increase in body weight among children.
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Affiliation(s)
- Jonas Englund
- Region Västernorrland, Regionens Hus, Härnösand, Sweden.
| | - Niclas Olofsson
- Department of Communication, Quality Management and Information Systems, Mid Sweden University, Sundsvall, Sweden
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Shabnam S, Zaccardi F, Yates T, Islam N, Razieh C, Chudasama YV, Banerjee A, Seidu S, Khunti K, Gillies CL. COVID-19 pandemic and risk factor measurement in individuals with cardio-renal-metabolic diseases: A retrospective study in the United Kingdom. PLoS One 2025; 20:e0319438. [PMID: 40273067 PMCID: PMC12021215 DOI: 10.1371/journal.pone.0319438] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/06/2024] [Accepted: 02/01/2025] [Indexed: 04/26/2025] Open
Abstract
BACKGROUND Comprehensive research about changes in risk factor (RF) management of people with chronic conditions during the COVID-19 pandemic is sparse. We aimed to study the impact of the pandemic on RF assessment in people with type 2 diabetes (T2DM), cardiovascular disease (CVD), and chronic kidney disease (CKD). METHOD Using UK Clinical Practice Research Datalink GOLD, we identified adults with T2DM, CVD and CKD who were alive and registered two years before (March 2018 - February 2019; March 2019 - February 2020) and one year during (March 2020 - February 2021) the pandemic. We estimated the proportion of people whose RFs (systolic (SBP) and diastolic (DBP) blood pressure, total cholesterol (TC), body mass index, smoking, and HbA1c) were assessed, mean values, and the proportion of controlled at each period for each cohort, overall and by age, sex, ethnicity, and deprivation. Multivariable logistic regression was used to estimate the association of patient characteristics (age, sex, ethnicity, deprivation, and comorbidity) with the outcome of having all RFs assessed during a given period. RESULTS Within the T2DM cohort, 66.4% and 65.2% had assessments of HbA1c in 2018 and 2019, which reduced to 43.4% in 2020. In CVD cohort, 76.9% and 72.6% had their BP measurements (54.5% and 51.3% for TC) in 2018 and 2019 respectively, which declined to 40.6% (30.7% for TC) in 2020. In CKD cohort, BP assessments declined from 77.9% and 72.3% in 2018 and 2019 respectively to 45.0% in 2020. These findings were consistent across patient demographics. In those with T2DM, SBP and DBP increased (+1.65 mmHg and +1.02 mmHg) in 2020. Elderly people were less likely to have all their RFs assessed in 2020 in all three cohorts compared to previous years. CONCLUSIONS Among people with major cardiometabolic conditions, there have been substantial reductions in the assessment and control of several key RFs during the pandemic. These patients will need regular monitoring in future for the prevention of complications. Our findings also highlight the need for resilient healthcare systems to ensure continuity of care and mitigate disparities in high-risk populations.
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Affiliation(s)
- Sharmin Shabnam
- Leicester Real World Evidence Unit, Leicester Diabetes Centre, Leicester, United Kingdom
| | - Francesco Zaccardi
- Leicester Real World Evidence Unit, Leicester Diabetes Centre, Leicester, United Kingdom
| | - Tom Yates
- National Institute for Health Research (NIHR) Leicester Biomedical Research Centre (BRC), Leicester Diabetes Centre, Leicester General Hospital, Leicester, United Kingdom
| | - Nazrul Islam
- Primary Care Research Centre, University of Southampton, Southampton, United Kingdom
| | - Cameron Razieh
- Leicester Real World Evidence Unit, Leicester Diabetes Centre, Leicester, United Kingdom
- Health Analysis and Life Events Division, Office for National Statistics, Newport, United Kingdom
| | - Yogini V Chudasama
- Leicester Real World Evidence Unit, Leicester Diabetes Centre, Leicester, United Kingdom
| | - Amitava Banerjee
- Institute of Health Informatics, University College London, London, United Kingdom
| | - Samuel Seidu
- Leicester Real World Evidence Unit, Leicester Diabetes Centre, Leicester, United Kingdom
| | - Kamlesh Khunti
- Leicester Real World Evidence Unit, Leicester Diabetes Centre, Leicester, United Kingdom
| | - Clare L Gillies
- Leicester Real World Evidence Unit, Leicester Diabetes Centre, Leicester, United Kingdom
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Nishida C, Honda H, Otsuka Y, Hagiya H, Nakano Y, Oguni K, Tokumasu K, Sakurada Y, Obika M, Otsuka F. Impact of Lifestyle Changes on Body Weight Gain During Nationwide Lockdown Due to COVID-19 Pandemic. J Clin Med 2025; 14:2242. [PMID: 40217694 PMCID: PMC11989682 DOI: 10.3390/jcm14072242] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/23/2025] [Revised: 03/19/2025] [Accepted: 03/23/2025] [Indexed: 04/14/2025] Open
Abstract
Background: During the coronavirus disease 2019 (COVID-19) pandemic, people in Japan were urged to stay at home as much as possible, and this resulted in significant changes in lifestyle behavior. The new lifestyle included factors affecting both energy intake and energy consumption, and it is now thought that weight gain during the lockdown was the result of complex effects. The aim of this study was to determine the relationships among lifestyle habits, laboratory data, and body weight gain during the lockdown using medical check-up data. Methods: A total of 3789 individuals who had undergone consecutive medical check-ups during the period from 2018 to 2020 were included in this study. Participants whose body weight had increased by 5% or more were divided into two groups: a before-lockdown group (participants who had gained weight between 2018 and 2019) and an after-lockdown group (participants who had gained weight between 2019 and 2020). Physical measurements, laboratory data, and answers to six questions about lifestyle habits, for which information was obtained from the records from medical check-ups, were compared in the two groups. Results: There was no significant difference between the distribution of weight changes in 2018-2019 before the lockdown and the distribution of weight changes in 2019-2020 after the lockdown. The before-lockdown and after-lockdown groups both included about 7% of the total participants (279 and 273 participants, respectively). Diastolic blood pressure and levels of AST, ALT, and LDL-C were significantly higher in the after-lockdown group than in the before-lockdown group. The percentages of participants with alcohol consumption and exercise habits were significantly higher in the after-lockdown group than in the before-lockdown group, and an analysis by gender showed that the differences were significant for women but not for men. Conclusions: The distributions of weight changes before and during the COVID-19 pandemic were similar. Exercise habits and alcohol consumption might have been unique factors causing weight gain during the COVID-19 pandemic, particularly in women. Our findings suggest that the impact of behavioral restrictions and lifestyle changes during a pandemic may be different in men and women.
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Affiliation(s)
| | - Hiroyuki Honda
- Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kitaku, Okayama 700-8558, Japan; (C.N.); (Y.O.); (H.H.); (Y.N.); (K.O.); (K.T.); (Y.S.); (M.O.); (F.O.)
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Kracht CL, Harville EW, Cohen NL, Sutton EF, Kebbe M, Redman LM. Trends in adverse pregnancy outcomes in Louisiana, 2017 to 2022. Sci Rep 2025; 15:9704. [PMID: 40113946 PMCID: PMC11926356 DOI: 10.1038/s41598-025-94092-0] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/07/2024] [Accepted: 03/11/2025] [Indexed: 03/22/2025] Open
Abstract
Natural disasters can lead to more adverse pregnancy outcomes (APO). It is unclear if the extended COVID-19 pandemic has impacted APOs and pre-existing conditions among perinatal populations with increased risk of severe maternal morbidity and mortality.A retrospective chart review was conducted of hospital records and birth certificates in the largest birth hospital in Louisiana from 2017 to 2022. Amongst 27,877 births (50.9% White, 38.3% Black, 28.9 ± 5.6 years), gestational diabetes (GDM) was lowest in pre-pandemic conceptions (11.0%, June 2017-May 2019) and rose to 16.4% early pandemic (October 2019-February 2020) but leveled off at 12.2% in peak (March 2020-February 2021) and late pandemic (March 2021-September 2021). Individuals who conceived in early and peak pandemic were 47% (95% CI 33, 63) and 11% (95% CI 2, 20) more likely to develop GDM respectively, compared to pre-pandemic conceptions. Individuals who delivered during early (aRR: 1.54, 95% CI 1.33-1.78), peak (aRR: 1.48, 95% CI 1.32-1.65), and late (aRR: 1.62, 95% CI 1.41, 1.85) pandemic were more likely to develop preeclampsia and HELLP syndrome compared to pre-pandemic conceptions. Individuals were also 17% (95% CI 5, 32) more likely to enter pregnancy with chronic hypertension in peak pandemic compared to pre-pandemic. In paired analysis (n = 3390), individuals with a pandemic conception that occurred early pandemic had a higher risk of developing GDM compared to their pre-pandemic pregnancy (aOR 3.26, 95% CI 1.52, 6.97). Supporting birthing individuals amongst significant stressful events, especially in early gestation, is critical for preventing APOs and severe maternal morbidity and mortality.
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Affiliation(s)
- Chelsea L Kracht
- Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA, 70808, USA
| | - Emily W Harville
- Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
| | - Nicole L Cohen
- Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
| | | | - Maryam Kebbe
- Faculty of Kinesiology, University of New Brunswick, Fredericton, NB, Canada
| | - Leanne M Redman
- Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA, 70808, USA.
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Männistö SA, Pietiläinen KH, Muotka J, Suojanen LU, Lappalainen R, Korpela R. Coach-Assisted eHealth With Group or Individual Support for Employees With Obesity: Randomized Controlled Trial on Weight, Body Composition, and Health Metrics. J Med Internet Res 2025; 27:e60436. [PMID: 40073400 PMCID: PMC11947631 DOI: 10.2196/60436] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/10/2024] [Revised: 09/11/2024] [Accepted: 01/29/2025] [Indexed: 03/14/2025] Open
Abstract
BACKGROUND Acceptance and commitment therapy provides a psychobehavioral framework feasible for digital and hybrid weight loss interventions. In face-to-face studies, group-based interventions yield more favorable outcomes than individual interventions, but the effect of the intervention form has not been studied in combination with eHealth. OBJECTIVE This study investigated whether a minimal, 3-session group or individual enhancement could provide additional benefits compared to an eHealth-only intervention when assessing weight, body composition, and laboratory metrics in a sample of occupational health patients with obesity. METHODS This study was a randomized controlled trial with a 12-month intervention, followed by a 12-month follow-up period without additional support (March 2021 to March 2023). Recruited from occupational health care for Finnish municipal employees, 111 working-age adults with a BMI of 30-40 kg/m2 were randomized to 1 of the 3 treatment arms: eHealth, eHealth+group, or eHealth+individual. All treatment arms received a web-administrated, coach-assisted eHealth program based on acceptance and commitment therapy, and additionally, the eHealth+group and eHealth+individual arms received 3 remotely facilitated group or individual meetings with their designated coach. The participants were assessed for weight, body composition, blood pressure, and laboratory measurements at 0-, 6-, 12-, and 24-month time points. Applying estimated means to decrease bias caused by dropouts, generalized estimating equations were used to study the differences between the 3 groups over time. RESULTS There were no between-group differences in primary measurements of weight change or categorical weight change. Secondary outcomes also did not show changes attributable to the intervention arm. Across the entire sample, the total weight loss was 1.5% during the intervention, with 18% (20/111) of the participants attaining a ≥5% weight loss. Sustained at follow-up, waist circumference decreased, and high-density lipoprotein cholesterol increased slightly. The participants completed, on average, 58.6% of the eHealth program. CONCLUSIONS There were no differences in weight or other somatic health variables between the eHealth arm and intervention combining eHealth with minimal group or individual enhancement. Despite a modest overall weight loss, the intervention shows promise in improving body composition and metabolic health. Moving forward, further research is needed to determine if there is a threshold where face-to-face meetings provide additional benefits in hybrid interventions. Moreover, there is a need to explore for whom and under what conditions eHealth and hybrid models may be most effective. TRIAL REGISTRATION ClinicalTrials.gov NCT04785586; https://clinicaltrials.gov/study/NCT04785586.
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Affiliation(s)
- Siniriikka A Männistö
- Occupational Health Helsinki, Helsinki, Finland
- HealthyWeightHub, Endocrinology, Abdominal Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
| | - Kirsi H Pietiläinen
- HealthyWeightHub, Endocrinology, Abdominal Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
- Obesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland
| | - Joona Muotka
- Department of Psychology, University of Jyväskylä, Jyväskylä, Finland
| | - Laura-Unnukka Suojanen
- HealthyWeightHub, Endocrinology, Abdominal Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
| | - Raimo Lappalainen
- Department of Psychology, University of Jyväskylä, Jyväskylä, Finland
| | - Riitta Korpela
- Department of Pharmacology, Faculty of Medicine, University of Helsinki, Helsinki, Finland
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Laskowski NM, Brandt G, Reque CB, Sabel L, Pahlenkemper M, Zaiser C, Paslakis G. The collateral effects of the COVID-19 pandemic: A gender-specific systematic review of disordered eating behaviour in the general population. EUROPEAN EATING DISORDERS REVIEW 2025; 33:254-288. [PMID: 39436325 PMCID: PMC11786942 DOI: 10.1002/erv.3141] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/27/2024] [Revised: 09/09/2024] [Accepted: 09/22/2024] [Indexed: 10/23/2024]
Abstract
OBJECTIVE The COVID-19 pandemic initiated public health measures, impacting mental health and exacerbating disordered eating behaviours (DEB). This study aims to fill gaps in understanding DEB in the general population during the pandemic, emphasising gender dynamics and the experiences of gender and/or sexual minority (SGM) individuals. METHOD A systematic literature review followed PRISMA guidelines to investigate DEB during the pandemic, focusing on gender-sensitive analyses and SGM populations. Outcomes from the included studies were synthesised to identify patterns and associations related to DEB, particularly considering gender dynamics and SGM experiences. RESULTS Significant gender associations with DEB were observed, with women consistently exhibiting higher scores. SGM populations also showed elevated DEB symptoms. Longitudinal studies indicated changes in DEB over time, with some decreases observed among men. CONCLUSIONS The review underscores significant gender differences in DEB during the pandemic, with women exhibiting higher symptom levels. Lockdown measures had nuanced impacts on DEB, varying across studies. Various factors including pandemic-related stressors influenced DEB. Consideration of these factors can inform tailored interventions for DEB in the general population. Overall, the review enhances our understanding of how gender intersects with the pandemic's impact on DEB, emphasising the need for diverse approaches to address these behaviours.
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Affiliation(s)
- Nora M. Laskowski
- Medical FacultyUniversity Clinic for Psychosomatic Medicine and PsychotherapyCampus East‐WestphaliaRuhr‐University BochumLuebbeckeGermany
| | - Gerrit Brandt
- Medical FacultyUniversity Clinic for Psychosomatic Medicine and PsychotherapyCampus East‐WestphaliaRuhr‐University BochumLuebbeckeGermany
| | - Cristina Ballero Reque
- Medical FacultyUniversity Clinic for Psychosomatic Medicine and PsychotherapyCampus East‐WestphaliaRuhr‐University BochumLuebbeckeGermany
| | - Luisa Sabel
- Medical FacultyUniversity Clinic for Psychosomatic Medicine and PsychotherapyCampus East‐WestphaliaRuhr‐University BochumLuebbeckeGermany
| | - Marie Pahlenkemper
- Medical FacultyUniversity Clinic for Psychosomatic Medicine and PsychotherapyCampus East‐WestphaliaRuhr‐University BochumLuebbeckeGermany
| | - Christopher Zaiser
- Medical FacultyUniversity Clinic for Psychosomatic Medicine and PsychotherapyCampus East‐WestphaliaRuhr‐University BochumLuebbeckeGermany
| | - Georgios Paslakis
- Medical FacultyUniversity Clinic for Psychosomatic Medicine and PsychotherapyCampus East‐WestphaliaRuhr‐University BochumLuebbeckeGermany
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11
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Henderson M, Moore SA, Harnois‐Leblanc S, Johnston BC, Fitzpatrick‐Lewis D, Usman AM, Sherifali D, Merdad R, Rigsby AM, Esmaeilinezhad Z, Morrison KM, Hamilton J, Ball GDC, Birken CS. Effectiveness of behavioural and psychological interventions for managing obesity in children and adolescents: A systematic review and meta-analysis framed using minimal important difference estimates based on GRADE guidance to inform a clinical practice guideline. Pediatr Obes 2025; 20:e13193. [PMID: 39823182 PMCID: PMC11803187 DOI: 10.1111/ijpo.13193] [Citation(s) in RCA: 2] [Impact Index Per Article: 2.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 05/24/2024] [Revised: 09/18/2024] [Accepted: 09/30/2024] [Indexed: 01/19/2025]
Abstract
OBJECTIVE Conduct a systematic review and meta-analysis of randomized controlled trials (RCTs) of behavioural and psychological interventions for managing paediatric obesity. METHODS Eligible studies, published between 1985 and 2022, included 0 to 18 year olds with outcomes reported ≥3 months post-baseline, including patient-reported outcome measures (PROMs), cardiometabolic and anthropometric outcomes, and adverse events (AEs). We pooled data using a random effects model and assessed certainty of evidence (CoE) related to minimally important difference estimates for outcomes using GRADE. RESULTS We included 73 unique RCTs (n = 6305 participants, 53% female). Intervention types included physical activity (n = 1437), nutrition (n = 447), psychological (n = 1336), technology-based (n = 901) or multicomponent (≥2 intervention types, n = 2184). Physical activity had a small effect on health-related quality of life (HRQoL), varying effects ranging from moderate to very large on blood pressure, lipids and insulin resistance, and a small effect on BMIz. Nutrition had a small effect on lipids, insulin resistance and BMIz. Psychological interventions showed a small effect on HRQoL and triglycerides and moderate benefits on depressive symptoms, while technology interventions showed small benefits on blood pressure and BMIz. Multicomponent interventions had a large benefit on anxiety, small benefit on depressive symptoms, with large to very large benefits on lipids, and small benefits for diastolic blood pressure, insulin resistance and BMIz. AEs were reported infrequently, and when reported, were described as mild. CONCLUSION Physical activity and multicomponent interventions showed improvements in PROMs, cardiometabolic and anthropometric outcomes. Future trials should consistently measure PROMs, evaluate outcomes beyond the intervention period, and study children <6 years of age.
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Affiliation(s)
- M. Henderson
- Sainte‐Justine University Hospital Research CenterUniversité de MontréalMontréalQuebecCanada
- Department of Pediatrics, Faculty of MedicineUniversité de MontréalMontréalQuebecCanada
- Department of Social and Preventive MedicineSchool of Public Health, Université de MontréalMontréalQuebecCanada
| | - S. A. Moore
- School of Health and Human Performance, Faculty of HealthDalhousie UniversityHalifaxNova ScotiaCanada
- Department of Pediatrics, Faculty of MedicineDalhousie UniversityHalifaxNova ScotiaCanada
| | - S. Harnois‐Leblanc
- Sainte‐Justine University Hospital Research CenterUniversité de MontréalMontréalQuebecCanada
- Department of Population MedicineHarvard Pilgrim Health Care Institute and Harvard Medical SchoolBostonMassachusettsUSA
| | - B. C. Johnston
- Department of NutritionCollege of Agriculture and Life Science, Texas A&M UniversityCollege StationTexasUSA
- Department of Epidemiology and BiostatisticsSchool of Public Health, Texas A&M UniversityCollege StationTexasUSA
| | - D. Fitzpatrick‐Lewis
- School of NursingMcMaster UniversityHamiltonOntarioCanada
- McMaster Evidence Review and Synthesis TeamMcMaster UniversityHamiltonOntarioCanada
| | - A. M. Usman
- McMaster Evidence Review and Synthesis TeamMcMaster UniversityHamiltonOntarioCanada
- Department of Health Research Methods, Evidence and Impact, Faculty of Health SciencesMcMaster UniversityHamiltonOntarioCanada
| | - D. Sherifali
- School of NursingMcMaster UniversityHamiltonOntarioCanada
- McMaster Evidence Review and Synthesis TeamMcMaster UniversityHamiltonOntarioCanada
| | - R. Merdad
- Department of Community Medicine, Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia
| | - A. M. Rigsby
- Department of NutritionCollege of Agriculture and Life Science, Texas A&M UniversityCollege StationTexasUSA
| | - Z. Esmaeilinezhad
- Department of NutritionCollege of Agriculture and Life Science, Texas A&M UniversityCollege StationTexasUSA
| | - K. M. Morrison
- Department of PediatricsMcMaster UniversityHamiltonOntarioCanada
- McMaster Children's HospitalHamiltonOntarioCanada
| | - J. Hamilton
- The Hospital for Sick ChildrenTorontoOntarioCanada
- Department of PediatricsUniversity of TorontoTorontoOntarioCanada
| | - G. D. C. Ball
- Department of Pediatrics, Faculty of Medicine & DentistryCollege of Health Sciences, University of AlbertaEdmontonAlbertaCanada
| | - C. S. Birken
- Department of PediatricsUniversity of TorontoTorontoOntarioCanada
- Child Health Evaluative Sciences, SickKids Research InstituteTorontoOntarioCanada
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12
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Nylander C, Nowicka P, Derwig M. The prevalence of overweight among 4-year-olds during and after the COVID-19 pandemic was associated with socioeconomic burden. Acta Paediatr 2025; 114:555-561. [PMID: 39452522 PMCID: PMC11828730 DOI: 10.1111/apa.17468] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 04/22/2024] [Revised: 10/04/2024] [Accepted: 10/09/2024] [Indexed: 10/26/2024]
Abstract
AIM To assess the prevalence of overweight among Swedish 4 year olds in 2018, 2020 and 2022, taking socioeconomic variables into account. METHODS Aggregated regional data on children's body mass index were collected. The socioeconomic Care Need Index (CNI), foreign background, low education, being a single parent, low income and childhood poverty, were assessed. The differences in overweight, including obesity, were tested for Sweden and for regions. RESULTS Data were available for 303 843 children, representing 87% of children born in 2014, 2016 and 2018. Overweight or obesity were found in 11 177 (11.4%) of children in 2022, decreasing from 2020 (13.3%, p < 0.001) but at the same level as in 2018. Regional low CNI, low level of foreign background, education and income as well as being a single parent were associated with a higher prevalence of overweight or obesity in all cohorts (p < 0.001). In regions with high levels of childhood poverty, overweight or obesity were more prevalent during (p = 0.009) and after the pandemic (p < 0.001). CONCLUSION Three national cohorts demonstrate that the increase in overweight during the COVID-19 pandemic has returned to pre-pandemic levels, but the inequalities in health associated with socioeconomic vulnerability of the regions remained.
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Affiliation(s)
- Charlotte Nylander
- Child Health Services SörmlandEskilstunaSweden
- Centre for Clinical Research SörmlandEskilstunaSweden
- Department of Women's and Children's HealthUppsala UniversityUppsalaSweden
| | - Paulina Nowicka
- Department of Food Studies, Nutrition and DieteticsUppsala UniversityUppsalaSweden
| | - Mariette Derwig
- Department of Clinical SciencesLunds UniversityLundsSweden
- Child Health Services SkåneLundsSweden
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13
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Molarius A, Karlsson J. Trends in obesity prevalence by gender and educational level among adults in Mid-Sweden between 2012 and 2022. J Epidemiol Community Health 2025; 79:216-219. [PMID: 39438138 DOI: 10.1136/jech-2024-222665] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/24/2024] [Accepted: 10/05/2024] [Indexed: 10/25/2024]
Abstract
BACKGROUND The aim was to investigate trends in obesity prevalence by gender and educational level in the general population aged 30-69 years, based on large surveys conducted in Mid-Sweden in 2012, 2017 and 2022. METHODS The study included 22 082, 15 264 and 17 055 respondents, respectively. Obesity (body mass index ≥30 kg/m2) was based on self-reported weight and height. Trends in obesity prevalence, including comparisons across educational levels, were estimated by age-standardised proportions with corresponding 95% CIs. Differences between genders, educational levels and survey years were tested using multiple logistic regression. RESULTS The overall age-standardised prevalence of obesity increased from 17.6% in 2012 to 20.1% in 2017 and to 23.3% in 2022. There was no statistically significant difference in obesity prevalence between men and women. Large and persisting inequalities between educational levels were however observed. In 2022, the prevalence of obesity was about 30% among persons with low/middle education and 18% among persons with high education. CONCLUSION Efforts to tackle the obesity epidemic are urgently required in Sweden, taking into consideration the circumstances of groups with low and middle levels of education.
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Affiliation(s)
- Anu Molarius
- Centre for Clinical Research, Region Värmland, Karlstad, Värmland, Sweden
- Department of Public Health Sciences, Karlstad University, Karlstad, Sweden
| | - Jan Karlsson
- University Health Care Research Center, Örebro University, Orebro, Sweden
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14
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Cerrai S, Carreras G, Monti F, Stival C, Lugo A, Bosetti C, Biagioni S, Fanucchi T, Gorini G, Amerio A, Mastrobattista L, Mortali C, Odone A, Molinaro S, Smits L, Gallus S, the “Lost in Italy” and “Lost in Toscana” Study Investigators *. Changes in Alcohol Consumption During and After the Covid-19 Pandemic From 2020 to 2023 in a Prospective Cohort of Italian Adults. J Epidemiol 2025; 35:63-70. [PMID: 39694502 PMCID: PMC11706678 DOI: 10.2188/jea.je20230340] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/01/2023] [Accepted: 03/14/2024] [Indexed: 12/20/2024] Open
Abstract
BACKGROUND The lockdowns imposed by the government during coronavirus disease 2019 (COVID-19) pandemic have had a significant impact on the Italian population habits. METHODS LOckdown and lifeSTyles in Italy and in Tuscany studies collected data on a representative sample of the Italian adult population in 2020 (n = 6,003) followed up through 2023 via four additional surveys (3,000 ≤ n ≤ 6,600) through an online self-administered questionnaire. The Alcohol Use Disorders Identification Test-Concise was used to identify at-risk drinkers. Considering the cohort of individuals who took part to the first and at least one other wave (n = 5,378), a multilevel logistic model was used to derive odds ratios (ORs) and corresponding 95% confidence intervals (CIs) of being at-risk drinkers. RESULTS The prevalence of at-risk drinkers was 26.4% before, 23.4% during the first lockdown, and stabilized around 30.0% thereafter. Being at-risk alcohol consumers decreased with decreasing economic status (P for trend <0.001), was less frequent among middle-aged compared to younger (OR 0.73; 95% CI, 0.60-0.89) and among divorced/separated (OR 0.77; 95% CI, 0.60-0.99) or single (OR 0.75; 95% CI, 0.64-0.89) compared to married individuals. It was more frequent among individuals with anxiety or depressive symptoms (OR 1.24; 95% CI, 1.12-1.37), those using psychotropic drugs (OR 1.99; 95% CI, 1.69-2.35) and users of conventional and/or alternative nicotine products (OR 3.67; 95% CI, 3.00-4.48). CONCLUSION The long-term trends in alcohol consumption after the COVID-19 pandemic are unfavorable in Italy. The results point to an increased vulnerability for at-risk alcohol consumption among younger individuals, women with higher economic status, and married individuals. At-risk drinking is strongly related to mental health symptoms and nicotine consumption.
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Affiliation(s)
- Sonia Cerrai
- National Research Council, Institute of Clinical Physiology (CNR-IFC), Pisa, Italy
- Department of Epidemiology, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The Netherlands
| | - Giulia Carreras
- Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy
| | - Filippo Monti
- Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy
| | - Chiara Stival
- Department of Medical Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
| | - Alessandra Lugo
- Department of Medical Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
| | - Cristina Bosetti
- Department of Medical Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
| | - Silvia Biagioni
- National Research Council, Institute of Clinical Physiology (CNR-IFC), Pisa, Italy
- Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy
| | - Tiziana Fanucchi
- Unit of Health Promotion, Epidemiology, and Government of Territorial Demand, ASST Fatebenefratelli Sacco, Milan, Italy
| | - Giuseppe Gorini
- Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy
| | | | | | | | - Anna Odone
- Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy
| | - Sabrina Molinaro
- National Research Council, Institute of Clinical Physiology (CNR-IFC), Pisa, Italy
| | - Luc Smits
- Department of Epidemiology, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The Netherlands
| | - Silvano Gallus
- Department of Medical Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
| | - the “Lost in Italy” and “Lost in Toscana” Study Investigators*
- National Research Council, Institute of Clinical Physiology (CNR-IFC), Pisa, Italy
- Department of Epidemiology, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The Netherlands
- Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy
- Department of Medical Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
- Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy
- Unit of Health Promotion, Epidemiology, and Government of Territorial Demand, ASST Fatebenefratelli Sacco, Milan, Italy
- University of Genoa, Genoa, Italy
- Istituto Superiore di Sanità, Rome, Italy
- Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy
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15
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Sydora BC, Wilke MS, Ghosh M, Vine DF. The Impact of the COVID-19 Pandemic on Health and Health Care Experience in Those With Polycystic Ovary Syndrome. Int J Womens Health 2025; 17:287-298. [PMID: 39925784 PMCID: PMC11806697 DOI: 10.2147/ijwh.s504439] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/04/2024] [Accepted: 01/22/2025] [Indexed: 02/11/2025] Open
Abstract
Purpose Polycystic Ovary Syndrome (PCOS) is a complex endocrine-metabolic disorder and is associated with a variety of health disorders. The management of PCOS requires a multidisciplinary health care approach. The COVID-19 pandemic affected access and delivery of health care. The aim of this study was to assess the impact of the pandemic on the health and health care experience of those affected by PCOS. Patients and Methods An online survey was conducted January 2021 to July 2022 in Canada, open to anyone who identified as having PCOS. Data collected in REDCap included questions on demographics, symptoms, and experience of PCOS management during the pandemic. Results The majority (59%) of respondents (n=194, mean age 34±8 years) experienced pandemic-related employment changes and self-reported a high stress level (73±21/100). Of those who reported changes in body weight, 58% gained weight, which they attributed to unhealthy eating habits and a lack of exercise during the pandemic, and 16% lost weight, which they credited to increased physical activity and a shift towards healthier eating habits. The respondents ascribed the impact of COVID-related changes to clinic cancellations, delayed appointments, long wait times for referrals and lab work, lack of access to exercise facilities and insufficient social support. Some respondents voluntarily reduced access to health care services to limit COVID exposure. COVID-19-related health status was perceived as more important than their own PCOS-related symptoms. Virtual appointments via telehealth were regarded as beneficial for 20% of users. Conclusion Individuals with PCOS reported an overall reduction in COVID-related access to health care and supports. Some adapted to the use of telemedicine, while others experienced increased stress due to a lack of access to health care and an inability to manage their PCOS symptoms. The pandemic further highlighted that those with PCOS often experience a lack of accessibility to multidisciplinary health care and supports needed to manage their condition.
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Affiliation(s)
- Beate C Sydora
- Metabolic and Cardiovascular Disease Laboratory, Faculty of Agricultural, Life & Environmental Sciences, University of Alberta, Edmonton, Canada
| | - Michaelann S Wilke
- Metabolic and Cardiovascular Disease Laboratory, Faculty of Agricultural, Life & Environmental Sciences, University of Alberta, Edmonton, Canada
| | - Mahua Ghosh
- Department of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada
| | - Donna F Vine
- Metabolic and Cardiovascular Disease Laboratory, Faculty of Agricultural, Life & Environmental Sciences, University of Alberta, Edmonton, Canada
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Han YY, Jo HN, Kim BM, Lee JS, Kim JM, Ryu DH, Kim DH, Park CS, Kang BC, Lee YW. Effects of NET-2201 ( Capsicum chinense L. cv.) on brown adipose tissue activation and white adipose tissue browning in high-fat-diet-induced obese mice. Food Sci Biotechnol 2025; 34:769-780. [PMID: 39958175 PMCID: PMC11822149 DOI: 10.1007/s10068-024-01692-z] [Citation(s) in RCA: 1] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/07/2024] [Revised: 08/12/2024] [Accepted: 08/19/2024] [Indexed: 02/18/2025] Open
Abstract
The present study explored the anti-obesity effects of NET-2201 (Capsicum chinense L. cv.), a non-pungent cultivated variety of chili pepper, and its underlying molecular mechanism in high-fat-diet (HFD)-induced obese mice. Administration of 50 mg/kg NET-2201 significantly inhibited body weight (BW) gain and reduced adipose tissue weight in obese mice. NET-2201 caused improvement in the expression levels of genes associated with lipid metabolism in white adipose tissue (WAT) to near-normal levels. Furthermore, NET-2201 significantly increased peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) and uncoupling protein 1 (UCP1) protein expressions in brown adipose tissue (BAT). Moreover, NET-2201 activated WAT browning by altering the expression levels of brown and beige adipocyte-selective genes, including UCP1, PGC-1α, and PR domain containing 16. Our results indicate that dietary NET-2201 mitigates BW gain by activating BAT and inducing WAT browning. Supplementary Information The online version contains supplementary material available at 10.1007/s10068-024-01692-z.
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Affiliation(s)
- Yoon-Young Han
- Herbal Hormone Research Institute, Naturalendo Tech Co., Ltd, Seongnam, 13486 Republic of Korea
| | - Ha-Neul Jo
- Herbal Hormone Research Institute, Naturalendo Tech Co., Ltd, Seongnam, 13486 Republic of Korea
| | - Bo-Mi Kim
- Herbal Hormone Research Institute, Naturalendo Tech Co., Ltd, Seongnam, 13486 Republic of Korea
| | - Jae-Sun Lee
- Herbal Hormone Research Institute, Naturalendo Tech Co., Ltd, Seongnam, 13486 Republic of Korea
| | - Ji-Min Kim
- Herbal Hormone Research Institute, Naturalendo Tech Co., Ltd, Seongnam, 13486 Republic of Korea
| | - Dae-Ho Ryu
- Herbal Hormone Research Institute, Naturalendo Tech Co., Ltd, Seongnam, 13486 Republic of Korea
| | - Dong-Hee Kim
- Herbal Hormone Research Institute, Naturalendo Tech Co., Ltd, Seongnam, 13486 Republic of Korea
| | - Chan-Sung Park
- Herbal Hormone Research Institute, Naturalendo Tech Co., Ltd, Seongnam, 13486 Republic of Korea
| | - Byoung-Cheorl Kang
- Department of Plant Science and Plant Genomics and Breeding Institute, Seoul National University, Seoul, 151-921 Republic of Korea
| | - Yong-Wook Lee
- Herbal Hormone Research Institute, Naturalendo Tech Co., Ltd, Seongnam, 13486 Republic of Korea
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17
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Strugnell C, Gaskin CJ, Becker D, Orellana L, Jackson M, Hillenaar M, Whelan J, Brown AD, Brown V, Bell C, Hayward J, Stephens LD, Jensen H, Gribben I, Coller L, Tatlock D, Lehman E, Allender S. COVID-19-related lockdowns and changes in overweight and obesity, movement behaviours, diet quality, and health-related quality of life among regional Australian primary school children: A repeat cross-sectional study. Pediatr Obes 2025; 20:e13195. [PMID: 39694877 PMCID: PMC11710946 DOI: 10.1111/ijpo.13195] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 09/05/2024] [Revised: 10/23/2024] [Accepted: 11/11/2024] [Indexed: 12/20/2024]
Abstract
BACKGROUND During the coronavirus disease 2019 (COVID-19) pandemic, the Australian state of Victoria (in particular, its capital, Melbourne) experienced some of the longest lockdowns in the world. OBJECTIVE This repeated cross-sectional study examined changes between March to June 2019 (pre-pandemic) and April to August 2022 (6 to 11 months following pandemic-related lockdowns) in overweight and obesity prevalence, physical activity, sedentary behaviour, sleep, diet quality, and health-related quality of life (HRQoL) among primary school children in north-east Victoria, Australia. METHODS Height and weight were measured for Grade 2, 4, and 6 students in 2019 (3889 children) and 2022 (1816 children). Grade 4 and 6 students self-reported on their movement behaviours, diet quality, and HRQoL. RESULTS Participation declined among schools (2019:56%, 2022:34%) and students (2019:87%, 2022:75%). Compared to children in 2019, children in 2022 had a higher prevalence of overweight and obesity; were less likely to have met guidelines for moderate-to-vigorous physical activity, recreational screen time, and vegetable consumption; had higher intakes of takeaway food, energy-dense nutrient-poor snacks, and sugar-sweetened beverages; and had lower HRQoL. CONCLUSION Children's health-related behaviours and outcomes seemed not to have returned to pre-pandemic levels 6 to 11 months after the final lockdowns lifted for their communities. Continued monitoring and interventions targeting the drivers of childhood obesity are urgently needed.
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Affiliation(s)
- Claudia Strugnell
- Institute for Physical Activity and NutritionDeakin UniversityGeelongVictoriaAustralia
- Global Centre for Preventative Health and Nutrition (GLOBE), Institute for Health TransformationDeakin UniversityGeelongVictoriaAustralia
| | - Cadeyrn J. Gaskin
- Global Centre for Preventative Health and Nutrition (GLOBE), Institute for Health TransformationDeakin UniversityGeelongVictoriaAustralia
| | - Denise Becker
- Biostatistics Unit, Faculty of HealthDeakin UniversityGeelongVictoriaAustralia
| | - Liliana Orellana
- Biostatistics Unit, Faculty of HealthDeakin UniversityGeelongVictoriaAustralia
| | - Michelle Jackson
- Global Centre for Preventative Health and Nutrition (GLOBE), Institute for Health TransformationDeakin UniversityGeelongVictoriaAustralia
| | - Monique Hillenaar
- Global Centre for Preventative Health and Nutrition (GLOBE), Institute for Health TransformationDeakin UniversityGeelongVictoriaAustralia
| | - Jillian Whelan
- Global Centre for Preventative Health and Nutrition (GLOBE), Institute for Health TransformationDeakin UniversityGeelongVictoriaAustralia
| | - Andrew D. Brown
- Global Centre for Preventative Health and Nutrition (GLOBE), Institute for Health TransformationDeakin UniversityGeelongVictoriaAustralia
| | - Vicki Brown
- Deakin Health Economics, Institute for Health TransformationDeakin UniversityGeelongVictoriaAustralia
| | - Colin Bell
- Global Centre for Preventative Health and Nutrition (GLOBE), Institute for Health TransformationDeakin UniversityGeelongVictoriaAustralia
| | - Josh Hayward
- Global Centre for Preventative Health and Nutrition (GLOBE), Institute for Health TransformationDeakin UniversityGeelongVictoriaAustralia
| | - Lena D. Stephens
- Global Centre for Preventative Health and Nutrition (GLOBE), Institute for Health TransformationDeakin UniversityGeelongVictoriaAustralia
| | - Hayley Jensen
- Global Centre for Preventative Health and Nutrition (GLOBE), Institute for Health TransformationDeakin UniversityGeelongVictoriaAustralia
| | - Izzy Gribben
- Global Centre for Preventative Health and Nutrition (GLOBE), Institute for Health TransformationDeakin UniversityGeelongVictoriaAustralia
| | - Lee Coller
- Global Centre for Preventative Health and Nutrition (GLOBE), Institute for Health TransformationDeakin UniversityGeelongVictoriaAustralia
| | - Diana Tatlock
- Global Centre for Preventative Health and Nutrition (GLOBE), Institute for Health TransformationDeakin UniversityGeelongVictoriaAustralia
| | - Elizabeth Lehman
- Department of General Practice, School of Public Health and Preventive MedicineMonash UniversityMelbourneVictoriaAustralia
| | - Steven Allender
- Global Centre for Preventative Health and Nutrition (GLOBE), Institute for Health TransformationDeakin UniversityGeelongVictoriaAustralia
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18
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Zaccagni L, Gualdi-Russo E. Reduced Physical Activity and Increased Weight Status in Children and Adolescents During the COVID-19 Pandemic: A Systematic Review. CHILDREN (BASEL, SWITZERLAND) 2025; 12:178. [PMID: 40003280 PMCID: PMC11854173 DOI: 10.3390/children12020178] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Received: 12/28/2024] [Revised: 01/25/2025] [Accepted: 01/27/2025] [Indexed: 02/27/2025]
Abstract
BACKGROUND/OBJECTIVES The COVID-19 pandemic has impacted the lifestyles of children and adolescents because of the restrictions imposed to contain the infection. This systematic review examined the possible reduction in children's and adolescents' physical activity and changes in their BMI and weight status. METHODS A systematic review (PROSPERO: CRD42024589208) of English-language studies published up to 1 October 2024 in individuals with a mean age between 6 and 18 years that investigated physical activity data before and during or after the pandemic and focused on their BMI and weight status according to age, sex, and country making use of PubMed, Web of Science, and Scopus, identified 1040 possible articles. RESULTS Following the PRISMA statement, 26 articles with a whole set of 138,737 children and adolescents were enclosed in the review. The majority of included articles were of moderate quality, as determined by the Newcastle-Ottawa Scale adapted for observational studies. The studies found a decrease in PA, an increase in sedentary activities during/after the lockdown, and an increase in BMI and prevalence of overweight and obesity, especially in males and 8-11-year-olds. CONCLUSIONS The interruption or restriction of outdoor physical activities and sports during the COVID-19 pandemic resulted in a more sedentary lifestyle among children and adolescents, contributing to an overall increase in BMI and obesity, with alarming implications for related health risks and other noncommunicable diseases. Therefore, the adverse effects of restrictive measures should be assessed when implementing public health strategies during pandemics.
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Affiliation(s)
- Luciana Zaccagni
- Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, 44121 Ferrara, Italy;
- Center for Exercise Science and Sports, University of Ferrara, 44123 Ferrara, Italy
| | - Emanuela Gualdi-Russo
- Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, 44121 Ferrara, Italy;
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19
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Prinkey T, Lundqvist A, García Velázquez R, Lilja E, Skogberg N. Factors associated with individual-level changes in BMI as a result of COVID-19 in the general- and migrant-origin populations in Finland. Glob Health Promot 2025:17579759241307946. [PMID: 39831430 DOI: 10.1177/17579759241307946] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/22/2025]
Abstract
AIMS There is limited information on changes in body mass index (BMI) due to the COVID-19 pandemic among persons of migrant origin. The aim of the present study was to examine factors associated with changes in BMI among the general- and migrant-origin populations in Finland. METHODS Longitudinal data to explore individual-level changes in self-reported BMI among migrant-origin persons (N = 3313) were obtained from the FinMonik Survey conducted in 2018 and the MigCOVID Survey conducted 2020-2021. Data for the general population reference group were obtained from the FinHealth 2017 Study conducted 2017-2018 and its follow-up conducted in 2020 (N = 2982). Logistic regression was applied to examine whether age, sex, education, economic activity, length of residence in Finland, language skills, smoking, alcohol usage, sleep, physical activity, snacking, and fruit and vegetable consumption were associated with an increase or decrease in BMI. A change in BMI was defined as a 5% or greater increase or decrease. RESULTS Twenty-seven per cent of the migrant-origin population experienced an increase in BMI, while 14% had a decrease in BMI. These results corresponded to figures observed among the general population in Finland (27% and 14%). Persons of migrant origin who were other than students or employed faced greater odds of an increase in BMI of at least 5% (OR = 1.71). In the general population, an increase in BMI of at least 5% had greater odds of occurring among women (OR = 1.61), those who were other than students or employed (OR = 1.68), those who increased their alcohol intake (OR = 1.64), those who increased their snacking (OR = 1.40) and decreased their fruit and vegetable intake (OR = 1.85). CONCLUSIONS Most examined factors applied differently to general- and migrant-origin populations and by migrant-origin group. These differences must be considered when planning future public health promotion efforts, particularly those during crisis situations.
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Affiliation(s)
- T Prinkey
- Finnish Institute for Health and Welfare, Helsinki, Finland
| | - A Lundqvist
- Finnish Institute for Health and Welfare, Helsinki, Finland
| | | | - E Lilja
- Finnish Institute for Health and Welfare, Helsinki, Finland
| | - N Skogberg
- Finnish Institute for Health and Welfare, Helsinki, Finland
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20
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Bustos-Arriagada E, Vásquez F, Etchegaray-Armijo K, López-Arana S. Nutritional Status of 8,128,014 Chilean and Immigrant Children and Adolescents Evaluated by the National Board of School Aid and Scholarships (JUNAEB) Between 2013 and 2023. Nutrients 2025; 17:327. [PMID: 39861455 PMCID: PMC11767989 DOI: 10.3390/nu17020327] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/04/2024] [Revised: 01/08/2025] [Accepted: 01/14/2025] [Indexed: 01/27/2025] Open
Abstract
INTRODUCTION Nutritional issues, including overweight and obesity, along with the rising number of immigrants facing their own nutritional problems, continue to keep Chile on alert. OBJECTIVE To evaluate the epidemiological and nutritional status changes among Chilean and immigrant boys, girls, and adolescents (BGA) in schools evaluated by the National Board of School Aid and Scholarships (JUNAEB) from 2013 to 2023. METHODS This descriptive study analyzed individual, anonymous, and de-identified data on the nutritional status of BGA in pre-kindergarten, kindergarten, first grade, fifth grade, and the first year of high school using the JUNAEB Nutritional Map. RESULTS The sample consisted of 8,128,014 BGA, 49.2% women and 50.8% men. In 2013, immigrant BGA represented 0.4% of the total number of children evaluated, and by 2023, this percentage increased to 7.9%. It was observed that Chilean BGA had a lower proportion of thinness, risk of thinness, stunting, and normal weight, but a higher proportion of overnutrition compared to immigrants, similar to observations made during the COVID-19 pandemic. Comparisons by sex showed that Chilean and immigrant women had a lower percentage of thinness, risk of thinness, obesity, severe obesity, and stunting, and a higher proportion of normal weight when compared to men. CONCLUSIONS The rise in immigrant BGA within the Chilean school system, together with the nutritional differences between both groups, highlights the need to consider these particularities when designing nutritional public policies in the health and education sectors.
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Affiliation(s)
- Edson Bustos-Arriagada
- Faculty of Medicine, Nutrition and Dietetics School, Universidad Finis Terrae, Pedro de Valdivia 1509, Providencia, Santiago 7501015, Chile; (F.V.); (K.E.-A.); (S.L.-A.)
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21
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Dakanalis A, Psara E, Pavlidou E, Papadopoulou SK, Antasouras G, Voulgaridou G, Kosti RI, Vorvolakos T, Mentzelou M, Ntovoli A, Chrysafi M, Androutsos O, Jacovides C, Serdari A, Giaginis C. The Impact of the COVID-19 Pandemic in the Interrelationships Among Mental Health, Nutritional Status and Lifestyle Factors of Older Adults: A Cross-Sectional Study in the Pre- and Post-Covid Periods. Nutrients 2025; 17:249. [PMID: 39861378 PMCID: PMC11767919 DOI: 10.3390/nu17020249] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/14/2024] [Revised: 01/03/2025] [Accepted: 01/08/2025] [Indexed: 01/27/2025] Open
Abstract
BACKGROUND/OBJECTIVES The COVID-19 pandemic has led to detrimental effects on diverse aspects of the mental and physical health of the general population worldwide. The elderly are more susceptible to COVID-19 infection compared to younger age groups. In this aspect, the purpose of the current survey is to evaluate the effect of the COVID-19 pandemic on the interrelationships among the sociodemographic and anthropometric characteristics, depressive behavior, quality of life, cognition status, physical activity and nutritional status of older adults. METHODS The present study constitutes a comparative, cross-sectional study of 4162 older adults (mean age ± standard deviation: 72.13 ± 8.1 years and 75.22 ± 8.2 years in the pre- and post-COVID-19 periods, respectively, and a male/female ratio of almost 1:1). We used validated questionnaires to assess depression, cognition function, quality of life, physical activity and nutritional status of the elderly in the pre-Covid and post-Covid periods. Relevant questionnaires were also used for collecting sociodemographic data, while anthropometric data were measured using standard protocols. RESULTS The present study finds that the COVID-19 pandemic influenced, in an independent manner, residence location, smoking status, overweight/obesity and abdominal obesity, depressive behavior, quality of life, cognition behavior, physical activity levels and nutritional status of the elderly. The COVID-19 pandemic was also related to employment and living status as well as family economic status. Nevertheless, the above three relationships were insignificant in the multivariate analysis. CONCLUSIONS The COVID-19 pandemic exerted deleterious effects on several aspects of the mental and physical health of the elderly, which appeared to strongly persist in the post-Covid period. Future prospective population-based and well-organized surveys should be conducted to establish whether there is a causality long-term effect of the COVID-19 pandemic on diverse aspects of the mental and physical health of the elderly.
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Affiliation(s)
- Antonios Dakanalis
- Department of Mental Health, Fondazione IRCSS San Gerardo dei Tintori, Via G.B. Pergolesi 33, 20900 Monza, Italy;
- Department of Medicine and Surgery, University of Milano Bicocca, Via Cadore 38, 20900 Monza, Italy
| | - Evmorfia Psara
- Department of Food Science and Nutrition, School of Environment, University of Aegean, 81400 Myrina, Lemnos, Greece; (E.P.); (E.P.); (G.A.); (M.M.); (M.C.); (C.J.)
| | - Eleni Pavlidou
- Department of Food Science and Nutrition, School of Environment, University of Aegean, 81400 Myrina, Lemnos, Greece; (E.P.); (E.P.); (G.A.); (M.M.); (M.C.); (C.J.)
| | - Sousana K. Papadopoulou
- Department of Nutritional Sciences and Dietetics, School of Health Sciences, International Hellenic University, 57400 Thessaloniki, Greece; (S.K.P.); (G.V.)
| | - Georgios Antasouras
- Department of Food Science and Nutrition, School of Environment, University of Aegean, 81400 Myrina, Lemnos, Greece; (E.P.); (E.P.); (G.A.); (M.M.); (M.C.); (C.J.)
| | - Gavriela Voulgaridou
- Department of Nutritional Sciences and Dietetics, School of Health Sciences, International Hellenic University, 57400 Thessaloniki, Greece; (S.K.P.); (G.V.)
| | - Rena I. Kosti
- Department of Nutrition and Dietetics, School of Physical Education Sport Sciences and Dietetics, University of Thessaly, 42132 Trikala, Greece; (R.I.K.); (O.A.)
| | - Theophanis Vorvolakos
- Department of Psychiatry, School of Medicine, Democritus University of Thrace, University Hospital of Alexandroupolis, 68100 Thrace, Greece; (T.V.); (A.S.)
| | - Maria Mentzelou
- Department of Food Science and Nutrition, School of Environment, University of Aegean, 81400 Myrina, Lemnos, Greece; (E.P.); (E.P.); (G.A.); (M.M.); (M.C.); (C.J.)
| | - Apostolia Ntovoli
- Department of Physical Education and Sport Sciences, Frederick University, Limassol 3080, Cyprus;
| | - Maria Chrysafi
- Department of Food Science and Nutrition, School of Environment, University of Aegean, 81400 Myrina, Lemnos, Greece; (E.P.); (E.P.); (G.A.); (M.M.); (M.C.); (C.J.)
| | - Odysseas Androutsos
- Department of Nutrition and Dietetics, School of Physical Education Sport Sciences and Dietetics, University of Thessaly, 42132 Trikala, Greece; (R.I.K.); (O.A.)
| | - Constantina Jacovides
- Department of Food Science and Nutrition, School of Environment, University of Aegean, 81400 Myrina, Lemnos, Greece; (E.P.); (E.P.); (G.A.); (M.M.); (M.C.); (C.J.)
- Department of Nutritional Sciences and Dietetics, School of Health Sciences, International Hellenic University, 57400 Thessaloniki, Greece; (S.K.P.); (G.V.)
| | - Aspasia Serdari
- Department of Psychiatry, School of Medicine, Democritus University of Thrace, University Hospital of Alexandroupolis, 68100 Thrace, Greece; (T.V.); (A.S.)
| | - Constantinos Giaginis
- Department of Food Science and Nutrition, School of Environment, University of Aegean, 81400 Myrina, Lemnos, Greece; (E.P.); (E.P.); (G.A.); (M.M.); (M.C.); (C.J.)
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Mottalib MM, Phan TLT, Bramante CT, Chute CG, Pyles LA, Beheshti R. Impact of COVID-19 Diagnosis on Weight Trajectories of Children in the US National COVID Cohort Collaborative. MEDRXIV : THE PREPRINT SERVER FOR HEALTH SCIENCES 2025:2025.01.03.25319927. [PMID: 39802785 PMCID: PMC11722509 DOI: 10.1101/2025.01.03.25319927] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Indexed: 01/16/2025]
Abstract
Background The COVID-19 pandemic has exacerbated the obesity epidemic, with both adults and children demonstrating rapid weight gain during the pandemic. However, the impact of having a COVID-19 diagnosis on this trend is not known. Methods Using longitudinal data from January 2019 to June 2023 collected by the US National Institute for Health's National COVID Cohort Collaborative (N3C), children (age 2-18 years) with positive COVID-19 test results (n=11,474, 53% male, mean [SD] age 5.57 [±3.29] years, 54% white, mean [SD] 5.2 [±2.9] BMI observations per participants) were matched with COVID-19 negative children with identical demographic characteristics and similar observation window. We compared BMI percentile trajectories between the COVID-19 positive and COVID-19 negative cohorts, with further evaluation performed on COVID-19 positive patients stratified by hospitalization status. Results COVID-19 positive patients had a greater increase in % B M I p 95 than COVID-19 negative patients (average increase of 2.34 (±7.73) compared to 1.46 (±6.09), p<0.0005). COVID-19 positive patients gained more weight after their diagnosis of COVID-19 than before. Non-hospitalized children gained more weight than hospitalized children (average increase in % B M I p 95 of 2.38 (±7.65)) compared to 1.87 (±8.54)). Mixed effect regression analyses demonstrated that these associations remained even after adjusting for time, demographics, and baseline % B M I p 95 . Conclusions Having a COVID-19 diagnosis was associated with more rapid weight gain, especially after diagnosis and early in the pandemic. Future research should explore the reasons for this association and the implications for future health emergencies.
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Affiliation(s)
| | | | | | | | - Lee A Pyles
- West Virginia University, Morgantown, WV, US
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23
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Artymiak P, Żegleń M, Kryst Ł. The Impact of the COVID-19 Pandemic on Waist and Hip Circumference and Selected Indicators Related to It Among Adolescents From the Kraków (Poland) Population. Am J Hum Biol 2025; 37:e24182. [PMID: 39492665 DOI: 10.1002/ajhb.24182] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/05/2024] [Revised: 09/27/2024] [Accepted: 10/24/2024] [Indexed: 11/05/2024] Open
Abstract
OBJECTIVES The aim of the study was to assess changes in waist and hip circumference, as well as the waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR) indices among adolescents (11-15-year-olds) from the Kraków during the COVID-19 pandemic. METHODS Cross-sectional studies were conducted in four main districts of the city in the years 2020 and 2022. The study group consisted of 1662 people. Measurements of height, waist circumference, and hip circumference were taken. The collected data were used to calculate the WHR and WHtR indices. Statistical analyses were performed using two-way ANOVA and post hoc Tukey's test, as well as the Kruskal-Wallis test, depending on the normality of distribution. RESULTS An increase in hip circumference was observed in most age groups of both sexes. Among 14-15-year-old boys, an increase in waist circumference was observed, while among girls, the majority of cohorts showed the opposite trend. Additionally, in most age groups, a decrease in the values of WHR and WHtR indices was observed in both sexes, except for boys aged 14-15. CONCLUSION The study found that government-imposed restrictions related to the COVID-19 pandemic had an impact on waist circumference, hip circumference, WHR, and WHtR indicators among adolescents aged 11-15 from Kraków. While some results showed regression, suggesting potential factors such as reduced physical activity or increased screen time contributing to deteriorating outcomes. On the other hand, not all results changed, which may be attributed to the absence of modifications in dietary habits or physical activity as government restrictions ceased.
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Affiliation(s)
- Paulina Artymiak
- Department of Anthropology, Faculty of Physical Education and Sport, University of Physical Education, Kraków, Poland
| | - Magdalena Żegleń
- Department of Anthropology, Faculty of Physical Education and Sport, University of Physical Education, Kraków, Poland
| | - Łukasz Kryst
- Department of Anthropology, Faculty of Physical Education and Sport, University of Physical Education, Kraków, Poland
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24
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Naveed MA, Neppala S, Chigurupati HD, Rehan MO, Ali A, Naveed H, Azeem B, Iqbal R, Mubeen M, Ahmed M, Fath AR, Paul T, Munir MB. Trends in stroke-related mortality in atrial fibrillation patients in the United States: Insights from the CDC WONDER database. AMERICAN HEART JOURNAL PLUS : CARDIOLOGY RESEARCH AND PRACTICE 2025; 49:100491. [PMID: 39760108 PMCID: PMC11696626 DOI: 10.1016/j.ahjo.2024.100491] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Received: 09/23/2024] [Revised: 11/29/2024] [Accepted: 12/01/2024] [Indexed: 01/03/2025]
Abstract
Background Stroke associated with atrial fibrillation (AF) is a significant cause of mortality. This study analyzed demographic trends and disparities in mortality rates due to stroke in AF patients aged ≥25 years. Methods A retrospective analysis was conducted to acquire death data using the Centers for Disease Control and Prevention database from 1999 to 2020. Age-adjusted mortality rates (AAMRs) were calculated per 100,000 persons, and trends were assessed using Average Annual Percentage Change (AAPC) and annual percent change (APC). Data were stratified by year, sex, race/ethnicity, and geographical regions. Results Between 1999 and 2020, AF-associated stroke contributed to 331,106 deaths among adults in this study population. Deaths occurred predominantly in medical facilities (43.2 %). The overall AAMR for AF-associated stroke decreased from 7.4 in 1999 to 6.4 in 2020, with an APC of -1.02 (p-value = 0.004). Additionally, AAMR showed a significant decline from 2015 to 2018 with an APC of -7.22 (p-value <0.000001), followed by a striking rise from 2018 to 2020 (APC: 4.98) (p-value = 0.0008). Women had slightly higher AAMR than men (men: 6.6; women: 7.1) (p value = 0.02). AAMRs varied among racial/ethnic groups, with Whites having the highest AAMR (7.4), followed by Blacks (5.4), American Indian or Alaska Natives (4.6), Asian or Pacific Islanders (4.5), and Hispanics (4.1). AAMRs decreased for all races except Blacks. Geographically, AAMRs ranged from 4.3 in Nevada to 11.9 in Vermont, with the Western region showing the highest mortality (AAMR: 7.9). Nonmetropolitan areas had slightly higher AAMRs than metropolitan areas, with both experiencing a decrease over the study period. Conclusion This analysis depicts significant demographic and geographic disparities in mortality rates attributed to stroke associated with AF. Targeted interventions and equitable healthcare access are crucial to mitigate these disparities and improve outcomes for this population.
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Affiliation(s)
- Muhammad Abdullah Naveed
- Department of Cardiology, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan
| | - Sivaram Neppala
- Division of Cardiology, The University of Texas Health Sciences Center, San Antonio, TX, USA
| | - Himaja Dutt Chigurupati
- Department of Internal Medicine, New York Medical College at Saint Michael's Medical Center, Newark, NJ 07102, USA
| | - Muhammad Omer Rehan
- Department of Cardiology, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan
| | - Ahila Ali
- Department of Cardiology, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan
| | - Hamza Naveed
- Department of Internal Medicine, Queen Elizabeth the Queen Mother Hospital, EKHUFT, Margate, Kent, United Kingdom
| | - Bazil Azeem
- Department of Cardiology, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, Pakistan
| | - Rabia Iqbal
- Department of Cardiology, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan
| | - Manahil Mubeen
- Department of Cardiology, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan
| | - Mashood Ahmed
- Department of Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan
| | - Ayman R. Fath
- Division of Cardiology, The University of Texas Health Sciences Center, San Antonio, TX, USA
| | - Timir Paul
- Department of Cardiovascular Sciences, Ascension St. Thomas Hospital, University of Tennessee Health Sciences Center, Nashville, TN, USA
| | - Muhammad Bilal Munir
- Department of Cardiac Electrophysiology, University of California Davis Health, Sacramento, CA, USA
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Núñez-Cortés R, López-Bueno R, Torres-Castro R, Calatayud J, Del Pozo Cruz B. Prevalence of cardiovascular risk factors according to Life's Essential 8 in children and adolescents during the COVID-19 pandemic: A systematic review and meta-analysis including 1 526 173 participants from 42 countries. Pediatr Obes 2025; 20:e13190. [PMID: 39611250 DOI: 10.1111/ijpo.13190] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 08/07/2024] [Revised: 09/26/2024] [Accepted: 09/30/2024] [Indexed: 11/30/2024]
Abstract
INTRODUCTION Cardiovascular health is a crucial aspect of overall health. The aim of this study was to estimate the prevalence of cardiovascular risk factors among children and adolescents during the COVID-19 pandemic based on the Life's Essential 8 domains. METHODS PubMed, Scopus and Web of Science were systematically searched until 24 February 2023. Studies had to meet the following criteria: (1) observational studies, (2) studies reporting proportion of selected risk factors, (3) studies involving children or adolescents, (4) studies that collected data during the COVID-19 pandemic and (5) studies with representative samples. The outcomes included were diet, physical activity, nicotine exposure, sleep health, obesity, dyslipidaemia, diabetes and elevated blood pressure. RESULTS Sixty-two studies with 1 526 173 participants from 42 countries were included. Of these, 41 studies were used in the meta-analyses. The overall pooled prevalence of risk factors in the behavioural domain was as follows: poor quality diet 26.69% (95% CI 0.00%-85.64%), inadequate physical activity 70.81% (95% CI 64.41%-76.83%), nicotine exposure 9.24% (95% CI 5.53%-13.77%) and sleep disorders 33.49% (95% CI 25.24%-42.28%). The overall pooled prevalence of risk factors in the health domain was as follows: obesity 16.21% (95% CI 12.71%-20.04%), dyslipidaemia 1.87% (95% CI 1.73%-2.01%), diabetes 1.17% (95% CI 0.83%-1.58%) and elevated blood pressure 11.87% (95% CI 0.26%-36.50%). CONCLUSIONS These results highlight the need for prevention strategies to maintain better cardiovascular health from an early age, particularly by increasing physical activity levels, sleep time and promoting the consumption of more fruits and vegetables.
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Affiliation(s)
- Rodrigo Núñez-Cortés
- Department of Physical Therapy, Faculty of Medicine, University of Chile, Santiago, Chile
- Physiotherapy in Motion Multispeciality Research Group (PTinMOTION), Department of Physiotherapy, University of Valencia, Valencia, Spain
| | - Rubén López-Bueno
- Department of Physical Medicine and Nursing, University of Zaragoza, Zaragoza, Spain
- Exercise Intervention for Health Research Group (EXINH-RG), Department of Physiotherapy, University of Valencia, Valencia, Spain
- National Research Centre for the Working Environment, Copenhagen, Denmark
| | - Rodrigo Torres-Castro
- Department of Physical Therapy, Faculty of Medicine, University of Chile, Santiago, Chile
- Department of Pulmonary Medicine, Hospital Clínic-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain
| | - Joaquín Calatayud
- Exercise Intervention for Health Research Group (EXINH-RG), Department of Physiotherapy, University of Valencia, Valencia, Spain
- National Research Centre for the Working Environment, Copenhagen, Denmark
| | - Borja Del Pozo Cruz
- Department of Sports Sciences, Faculty of Medicine, Health, and Sports, Universidad Europea de Madrid, Villaviciosa de Odón, Madrid, Spain
- Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
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Simpson SE, Malek AM, Wen CC, Neelon B, Wilson DA, Mateus J, Pearce J, Chundru KJ, Korte JE, Florez H, Alkis M, Finneran M, Hunt KJ. Trends in Gestational Weight Gain and Prepregnancy Obesity in South Carolina, 2015-2021. Prev Chronic Dis 2024; 21:E98. [PMID: 39666870 PMCID: PMC11640805 DOI: 10.5888/pcd21.240137] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/14/2024] Open
Abstract
Introduction We examined trends in prepregnancy obesity and gestational weight gain, with a focus on racial and ethnic differences, before and during the COVID-19 pandemic in South Carolina. Methods Hospital and emergency department discharge codes were linked to birth certificates. Prepregnancy obesity was defined as a body mass index (kg/m2) of 30 or higher. Gestational weight gain was defined as inadequate, adequate, or excessive based on the 2009 Institute of Medicine guidelines. A generalized linear model with a multinomial distribution and glogit link estimated the risk of inadequate weight gain and excessive weight gain with adequate weight gain as the reference group. The generalized linear model with a modified Poisson distribution and log link estimated prepregnancy obesity risk with nonobese as the reference group. Results Our study included 306,344 full-term, singleton live births among 239,597 mothers from 2015 through 2021. The prevalence of inadequate weight gain increased across all racial and ethnic groups prepandemic (relative risk [RR] = 1.02; 95% CI, 1.01-1.02) and attenuated during the pandemic (RR = 0.99; 95% CI, 0.96-1.01). The prevalence of excessive weight gain was high and remained stable across all races and ethnicities before and during the pandemic. The prevalence of prepregnancy obesity increased across all racial and ethnic groups prepandemic; the prevalence after the start of the pandemic increased only among women of "other" races and ethnicities (RR = 1.12; 95% CI, 1.05-1.19) while attenuating among Hispanic, non-Hispanic Black, and non-Hispanic White women. Conclusion The COVID-19 pandemic did not alter trends of gestational weight gain; however, it did have a small effect on trends in prepregnancy obesity, with differential effects across racial and ethnic groups. The prevalence of prepregnancy obesity, inadequate weight gain, and excessive weight gain remains high among pregnant women in South Carolina. Obesity and weight gain are risk factors for many adverse maternal and infant pregnancy outcomes. Their high prevalence indicates the importance of developing effective weight management programs for women of childbearing age and pregnant women.
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Affiliation(s)
- Sarah E Simpson
- Department of Public Health Sciences, Medical University of South Carolina, 135 Cannon St, Ste 302, Charleston, SC 29425
| | - Angela M Malek
- Department of Public Health Sciences, Medical University of South Carolina, Charleston
| | - Chun-Che Wen
- Department of Public Health Sciences, Medical University of South Carolina, Charleston
| | - Brian Neelon
- Department of Public Health Sciences, Medical University of South Carolina, Charleston
- Health Equity and Rural Outreach Innovation Center, Ralph H. Johnson Department of Veterans Affairs Medical Center, Charleston
| | - Dulaney A Wilson
- Department of Public Health Sciences, Medical University of South Carolina, Charleston
| | - Julio Mateus
- Department of Obstetrics and Gynecology, Maternal-Fetal Medicine Division, Atrium Health, Charlotte, North Carolina
| | - John Pearce
- Department of Public Health Sciences, Medical University of South Carolina, Charleston
| | - Kalyan J Chundru
- Department of Public Health Sciences, Medical University of South Carolina, Charleston
| | - Jeffrey E Korte
- Department of Public Health Sciences, Medical University of South Carolina, Charleston
| | - Hermes Florez
- Department of Public Health Sciences, Medical University of South Carolina, Charleston
- Health Equity and Rural Outreach Innovation Center, Ralph H. Johnson Department of Veterans Affairs Medical Center, Charleston
| | - Mallory Alkis
- Department of Obstetrics & Gynecology, Medical University of South Carolina, Charleston
| | - Matt Finneran
- Department of Obstetrics & Gynecology, Medical University of South Carolina, Charleston
| | - Kelly J Hunt
- Department of Public Health Sciences, Medical University of South Carolina, Charleston
- Health Equity and Rural Outreach Innovation Center, Ralph H. Johnson Department of Veterans Affairs Medical Center, Charleston
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Sarintohe E, Burk WJ, Vink JM, Larsen JK. Changes in Body Mass Index during the COVID-19 Pandemic among Indonesian Adolescents: The Role of Sex, Urban Area, Baseline BMI, and Appetitive Traits. Obes Facts 2024; 18:169-177. [PMID: 39662071 PMCID: PMC12017751 DOI: 10.1159/000543078] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 12/06/2023] [Accepted: 12/03/2024] [Indexed: 12/13/2024] Open
Abstract
INTRODUCTION Little is known about how the COVID-19 situation affected weight development among Indonesian adolescents. This longitudinal study examined whether, and for whom, the COVID-19 situation affected weight outcomes over time among adolescents from private schools and higher socio-economic positions in Indonesia, where being overweight is a rather prevalent characteristic. This study specifically examined whether appetitive traits (i.e., emotional overeating, food responsiveness) as well as baseline zBMI, sex, and urban area could explain changes in zBMI. METHODS At baseline, 411 adolescents from 5 private schools in Indonesia (53.3% males, Mage = 12.02 years, SD = 0.45) filled out questionnaires on appetitive traits and background characteristics. In addition, their height and weight were measured. Of these, 336 adolescents (81.8%) also participated at follow-up. At follow-up, height and weight were measured or reported. We used linear regression to analyze the association between predictors and interactions with zBMI. RESULTS The results showed a significant decrease in zBMI over time, with a lower average zBMI during COVID-19 compared to before COVID-19. Female adolescents and adolescents with higher baseline zBMI values particularly tended to show this zBMI decreasing pattern. We did not find statistically significant main effects of baseline emotional overeating, food responsiveness, and urban area or any interactions. CONCLUSIONS Indonesian adolescents appeared to decrease in terms of zBMI during COVID-19, particularly females and adolescents with higher pre-COVID-19 zBMI. Our findings suggest that (culturally-specific) contextual changes (i.e., less exposure to the Indonesian food environment at schools and more exposure to the home environment) might have a beneficial impact in terms of preventing overweight among Indonesian adolescents, particularly among those being more vulnerable (i.e., having higher baseline zBMI).
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Affiliation(s)
- Eveline Sarintohe
- Behavioural Science Institute, Radboud University, Nijmegen, The Netherlands
- Psychology Faculty, Maranatha Christian University, Bandung, Indonesia
| | - William J. Burk
- Behavioural Science Institute, Radboud University, Nijmegen, The Netherlands
| | - Jacqueline M. Vink
- Behavioural Science Institute, Radboud University, Nijmegen, The Netherlands
| | - Junilla K. Larsen
- Behavioural Science Institute, Radboud University, Nijmegen, The Netherlands
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Varghese JS, Guo Y, Ali MK, Donahoo WT, Chakkalakal RJ. Body mass index changes and their association with SARS-CoV-2 infection: a real-world analysis. Int J Obes (Lond) 2024; 48:1785-1792. [PMID: 39277656 PMCID: PMC12065624 DOI: 10.1038/s41366-024-01628-x] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 02/06/2024] [Revised: 08/29/2024] [Accepted: 09/02/2024] [Indexed: 09/17/2024]
Abstract
OBJECTIVE To study body mass index (BMI) changes among individuals aged 18-99 years with and without SARS-CoV-2 infection. SUBJECTS/METHODS Using real-world data from the OneFlorida+ Clinical Research Network of the National Patient-Centered Clinical Research Network, we compared changes over time in BMI in an Exposed cohort (positive SARS-CoV-2 test between March 2020-January 2022), to a contemporary Unexposed cohort (negative SARS-CoV-2 tests), and an age/sex-matched Historical control cohort (March 2018-January 2020). BMI (kg/m2) was retrieved from objective measures of height and weight in electronic health records. We used target trial approaches to estimate BMI at start of follow-up and change per 100 days of follow-up for Unexposed and Historical cohorts relative to the Exposed cohort by categories of sex, race & ethnicity, age, and hospitalization status. RESULTS The study sample consisted of 249,743 participants (19.2% Exposed, 61.5% Unexposed, 19.3% Historical cohort) of whom 62% were women, 21.5% Non-Hispanic Black, 21.4% Hispanic and 5.6% Non-Hispanic other and had an average age of 51.9 years (SD: 18.9). At start of follow-up, relative to the Unexposed cohort (mean BMI: 29.3 kg/m2 [95% CI: 29.1, 29.4]), the Exposed (0.07 kg/m2 [95% CI; 0.01, 0.12]) had higher mean BMI and Historical controls (-0.20 kg/m2 [95% CI; -0.25, -0.15]) had lower mean BMI. Over 100 days, BMI did not change (0 kg/m2 [95% CI: -0.03, 0.03]) for the Exposed cohort, decreased (-0.04 kg/m2 [95% CI; -0.05, -0.02]) for the Unexposed cohort and increased (0.03 kg/m2 [95% CI; 0.01, 0.04]) for the Historical cohort. Observed differences in BMI at start of follow-up and over 100 days were consistent between Unexposed and Exposed cohorts for most subgroups, except at start of follow-up period among Males and those 65 years or older who had lower BMI among Exposed. CONCLUSIONS In a diverse real-world cohort of adults, mean BMI of those with and without SARS-CoV2 infection varied in their trajectories. The mechanisms and implications of weight retention following SARS-CoV-2 infection remain unclear.
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Affiliation(s)
- Jithin Sam Varghese
- Emory Global Diabetes Research Center of Woodruff Health Sciences Center and Emory University, Atlanta, GA, USA
- Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA
| | - Yi Guo
- Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL, USA
| | - Mohammed K Ali
- Emory Global Diabetes Research Center of Woodruff Health Sciences Center and Emory University, Atlanta, GA, USA
- Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA
- Department of Family and Preventive Medicine, School of Medicine, Emory University, Atlanta, GA, USA
| | - W Troy Donahoo
- Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, College of Medicine University of Florida, Gainesville, FL, USA
| | - Rosette J Chakkalakal
- Emory Global Diabetes Research Center of Woodruff Health Sciences Center and Emory University, Atlanta, GA, USA.
- Department of Family and Preventive Medicine, School of Medicine, Emory University, Atlanta, GA, USA.
- Department of Medicine, School of Medicine, Emory University, Atlanta, GA, USA.
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Gupta M, Eckrich D, Bunnell HT, Phan TLT, Beheshti R. Reliable prediction of childhood obesity using only routinely collected EHRs may be possible. OBESITY PILLARS 2024; 12:100128. [PMID: 39315061 PMCID: PMC11417568 DOI: 10.1016/j.obpill.2024.100128] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 05/26/2024] [Revised: 08/21/2024] [Accepted: 08/22/2024] [Indexed: 09/25/2024]
Abstract
Background Early identification of children at high risk of obesity can provide clinicians with the information needed to provide targeted lifestyle counseling to high-risk children at a critical time to change the disease course. Objectives This study aimed to develop predictive models of childhood obesity, applying advanced machine learning methods to a large unaugmented electronic health record (EHR) dataset. This work improves on other studies that have (i) relied on data not routinely available in EHRs (like prenatal data), (ii) focused on single-age predictions, or (iii) not been rigorously validated. Methods A customized sequential deep-learning model to predict the development of obesity was built, using EHR data from 36,191 diverse children aged 0-10 years. The model was evaluated using extensive discrimination, calibration, and utility analysis; and was validated temporally, geographically, and across various subgroups. Results Our results are mostly better or comparable to similar studies. Specifically, the model achieved an AUROC above 0.8 in all cases (with most cases around 0.9) for predicting obesity within the next 3 years for children 2-7 years of age. Validation results show the model's robustness and top predictors match important risk factors of obesity. Conclusions Our model can predict the risk of obesity for young children at multiple time points using only routinely collected EHR data, greatly facilitating its integration into clinical care. Our model can be used as an objective screening tool to provide clinicians with insights into a patient's risk for developing obesity so that early lifestyle counseling can be provided to prevent future obesity in young children.
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Affiliation(s)
- Mehak Gupta
- Southern Methodist University, Dallas, TX, USA
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Gu L, Yang L, Li H. Investigating the impact of the COVID-19 pandemic on the nutritional status of infants and toddlers: insights from China. Popul Health Metr 2024; 22:31. [PMID: 39533281 PMCID: PMC11556185 DOI: 10.1186/s12963-024-00353-x] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/25/2024] [Accepted: 11/06/2024] [Indexed: 11/16/2024] Open
Abstract
BACKGROUND A comprehensive understanding of the impact of the COVID-19 pandemic on childhood nutrition is crucial for devising effective mitigation strategies. However, existing knowledge regarding the pandemic's effect on childhood nutritional status remains limited. Furthermore, research focusing on young children aged 0-3 years is scarce. METHODS Leveraging the outbreak that originated in Wuhan in Dec 2019, the epicenter of China's first and largest outbreak, and national survey and statistical yearbook data, this study conducted a natural experimental analysis with the consideration of geographical exposure, temporal exposure and survey cohort effects to investigate the pandemic's impacts on varying nutritional indicators of infants and toddlers aged 0-36 months. A comprehensive set of sensitivity analyses, robustness checks and falsification tests were conducted. The potential heterogeneities across socioeconomic and age groups were also examined. RESULTS The pandemic was robustly predictive of a higher weight-for-age z-score (WAZ) and length/height-for-age z-score (HAZ), and a lower likelihood of underweight. The effects of the pandemic on increasing WAZ and reducing underweight were more pronounced among children from economically disadvantaged backgrounds or aged 0-12 months. Additionally, the increasing HAZ was primarily among children from households with lower family income. Moreover, the pandemic was negatively linked to the body mass index (BMI)-for-age z-score (BAZ) of children residing in more developed cities, and positively linked to overweight/obesity among children aged 13-24 months. CONCLUSIONS This study adds to a more comprehensive understanding of the impact of the COVID-19 pandemic on childhood nutrition. Notably, the findings highlight that weight gain attributable to the pandemic was predominantly among vulnerable children from disadvantaged backgrounds and younger age groups, who were already at a higher risk of overweight/obesity before the pandemic. Consequently, our findings imply the necessity of greater caution to the widened gap in childhood malnutrition post-pandemic. Furthermore, the study emphasizes the importance of implementing adaptable strategies with the consideration of social justice to safeguard all children's right to optimal growth from exogenous shocks and to achieve the children-related SDGs by 2030.
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Affiliation(s)
- Lijuan Gu
- Key Laboratory of Land Surface Pattern and Simulation, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, 11 A Datun Road, Beijing, 100101, People's Republic of China.
| | - Linsheng Yang
- Key Laboratory of Land Surface Pattern and Simulation, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, 11 A Datun Road, Beijing, 100101, People's Republic of China
- College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100101, People's Republic of China
| | - Hairong Li
- Key Laboratory of Land Surface Pattern and Simulation, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, 11 A Datun Road, Beijing, 100101, People's Republic of China
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Goldsack AJ, Marzan MB, Rolnik DL, Lindquist AC, Said JM, Palmer KR, Sheehan PM, Potenza S, Pritchard N, Whitehead CL, Ford J, Mol BW, Walker SP, Hui L. Trends in maternal body mass index, macrosomia and caesarean section in first-time mothers during the pandemic: a multicentre retrospective cohort study of 12 Melbourne public hospitals. BMC Pregnancy Childbirth 2024; 24:706. [PMID: 39468519 PMCID: PMC11514852 DOI: 10.1186/s12884-024-06908-y] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/13/2024] [Accepted: 10/17/2024] [Indexed: 10/30/2024] Open
Abstract
OBJECTIVE To compare specific perinatal outcomes in nulliparas with a singleton infant in cephalic presentation at term, with and without exposure to the COVID-19 pandemic during pregnancy. We hypothesised that the pandemic conditions in Melbourne may have been an independent contributor to trends in maternal Body Mass Index ≥ 25 kg/m2, macrosomia and caesarean section. DESIGN Multi-centre retrospective cohort study and interrupted time-series analysis. SETTING Metropolitan Melbourne, Victoria. POPULATION Singleton infants ≥ 20 weeks gestational age born between 1 January 2019 and 31 March 2022. MAIN OUTCOME MEASURES Rates of maternal Body Mass Index ≥ 25 kg/m2, macrosomia (birthweight ≥ 4000 g) and caesarean section. RESULTS 25 897 individuals gave birth for the first time to a singleton infant in cephalic presentation at term in the pre-pandemic cohort, and 25 298 in the pandemic-exposed cohort. Interrupted time-series analysis demonstrated no significant additional effect of the pandemic on pre-existing upward trends in maternal Body Mass Index ≥ 25 kg/m2, caesarean section or macrosomia. The rate of maternal Body Mass Index ≥ 25 kg/m2 was higher in the pandemic-exposed cohort compared with the pre-pandemic cohort, (45.82% vs. 44.58% respectively, p = 0.041) as was the overall rate of caesarean section (33.09% vs. 30.80%, p < 0.001). However, this increase in caesarean section was confined to individuals who had either an induction of labour or no labour. There was also a nonsignificant trend to higher rates of macrosomia in the pandemic-exposed cohort compared with the pre-pandemic cohort (8.55% vs. 7.99% respectively, p = 0.124). CONCLUSIONS While rates of Body Mass Index ≥ 25 kg/m2, pre-labour caesarean section, and caesarean section following induction of labour were higher among pandemic-exposed nulliparas, these findings represented a continuation of pre-existing upward trends, with no significant independent contribution from the pandemic. These trends are forecast to continue, with long term implications for population health.
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Affiliation(s)
- Andrew J Goldsack
- Melbourne Medical School, The University of Melbourne, Melbourne, Australia
| | - Melvin B Marzan
- Department of Obstetrics, Gynaecology and Newborn Health, Melbourne Medical School, The University of Melbourne, Melbourne, Australia
- Department of Obstetrics and Gynaecology, Mercy Hospital for Women, Mercy Health, Melbourne, Australia
- Reproductive Epidemiology Group, Murdoch Children's Research Institute, Melbourne, Australia
| | - Daniel L Rolnik
- Department of Obstetrics and Gynaecology, Monash Health, Melbourne, Australia
- Department of Obstetrics and Gynaecology, Monash University, Melbourne, Australia
| | - Anthea C Lindquist
- Department of Obstetrics, Gynaecology and Newborn Health, Melbourne Medical School, The University of Melbourne, Melbourne, Australia
- Department of Obstetrics and Gynaecology, Mercy Hospital for Women, Mercy Health, Melbourne, Australia
| | - Joanne M Said
- Department of Obstetrics, Gynaecology and Newborn Health, Melbourne Medical School, The University of Melbourne, Melbourne, Australia
- Maternal-Fetal Medicine Department, Joan Kirner Women's and Children's Hospital, Western Health, Melbourne, Australia
| | - Kirsten R Palmer
- Department of Obstetrics and Gynaecology, Monash Health, Melbourne, Australia
- Department of Obstetrics and Gynaecology, Monash University, Melbourne, Australia
| | - Penelope M Sheehan
- Department of Obstetrics and Gynaecology, Monash Health, Melbourne, Australia
- Department of Obstetrics and Gynaecology, Eastern Health, Melbourne, Australia
| | - Stephanie Potenza
- Department of Obstetrics and Gynaecology, Mercy Hospital for Women, Mercy Health, Melbourne, Australia
| | - Natasha Pritchard
- Department of Obstetrics, Gynaecology and Newborn Health, Melbourne Medical School, The University of Melbourne, Melbourne, Australia
- Department of Obstetrics and Gynaecology, Mercy Hospital for Women, Mercy Health, Melbourne, Australia
| | - Clare L Whitehead
- Department of Obstetrics, Gynaecology and Newborn Health, Melbourne Medical School, The University of Melbourne, Melbourne, Australia
- Department of Obstetrics and Gynaecology, The Royal Women's Hospital, Melbourne, Australia
| | - Jolyon Ford
- Department of Obstetrics and Gynaecology, Peninsula Health, Melbourne, Australia
| | - Ben W Mol
- Department of Obstetrics and Gynaecology, Monash Health, Melbourne, Australia
- Department of Obstetrics and Gynaecology, Monash University, Melbourne, Australia
| | - Susan P Walker
- Department of Obstetrics, Gynaecology and Newborn Health, Melbourne Medical School, The University of Melbourne, Melbourne, Australia
- Department of Obstetrics and Gynaecology, Mercy Hospital for Women, Mercy Health, Melbourne, Australia
| | - Lisa Hui
- Department of Obstetrics, Gynaecology and Newborn Health, Melbourne Medical School, The University of Melbourne, Melbourne, Australia.
- Department of Obstetrics and Gynaecology, Mercy Hospital for Women, Mercy Health, Melbourne, Australia.
- Reproductive Epidemiology Group, Murdoch Children's Research Institute, Melbourne, Australia.
- Department of Obstetrics and Gynaecology, The Northern Hospital, Northern Health, Melbourne, Australia.
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Styk W, Wojtowicz E, Glibowski P, Iłowiecka K, Jędryszek-Geisler A, Zmorzyński S. Body image is associated with persistence. A study of the role of weight-related stigma. Front Psychiatry 2024; 15:1464939. [PMID: 39524127 PMCID: PMC11549672 DOI: 10.3389/fpsyt.2024.1464939] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 07/15/2024] [Accepted: 09/27/2024] [Indexed: 11/16/2024] Open
Abstract
Abstract The study replicates a preliminary report from 2019 on therelationship between body image and persistence. Purpose The aim of our study was to analyze the associations between body image, persistence, and body weight stereotypes. Patients and methods A total of 750 individuals were recruited for the study. The research was carried out in computer labs. The procedure consisted of psychological questionnaires (Persistence Scale, The Body Esteem Scale, Perceived Weight Stigma Questionnaire, Weight Bias Internalization Scale, Hospital Anxiety and Depression Scale, Formal Characteristics of Behavior - Temperament Inventory, and NEO-PI-R) and The Maze Test (a computer tool). After completing the Simple Maze Test, saliva samples were collected. Next, the subjects proceeded to the laboratory where anthropometric and body composition measurements were taken. The hormone levels (cortisol and dehydroepiandrosterone) in the collected saliva samples were analyzed via ELISA to determine stress. Results Body image and persistence are related variables. They are associated with the internalization of stereotypes and perceived stigma related to body weight. These associations are differentially shaped according to sex and the regularity of body weight. In women, a stronger association of these variables with body image was observed, while in men, the relationship with body image was weaker, with a stronger association shown by perceived weight-related stigma. In the group of participants with a BMI<18.5, there was no significant association between the internalization of stereotypes and the analyzed variables. This relationship appeared in the group of subjects with a normal body weight and was strongest in the group of participants who were overweight or obese. Perceived weight-related stigma was most strongly associated with body image in the group with BMI<18.5 kg/m2 and with persistence in the group with BMI>25 kg/m2. Conclusion Body-related stigma affects not only overweight and obese individuals and its mechanisms may be shaped differently.
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Affiliation(s)
- Wojciech Styk
- Academic Laboratory of Psychological Tests, Medical University of Lublin, Lublin, Poland
| | - Ewa Wojtowicz
- Chair of Pedeutology and Psychology of Education, Christian Theological Academy of Warsaw, Warsaw, Poland
| | - Paweł Glibowski
- Department of Biotechnology, Microbiology and Human Nutrition, Faculty of Food Sciences and Biotechnology, University of Life Sciences in Lublin, Lublin, Poland
| | - Katarzyna Iłowiecka
- Nutrition Clinic, Department of Clinical Dietetics Medical University of Lublin, Lublin, Poland
| | - Aleksanda Jędryszek-Geisler
- Department of Psychology, Institute of Pedagogy and Psychology, Management Academy of Applied Sciences in Warsaw, Warsaw, Poland
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Ergün U, Aktepe E, Koca YB. Detection of body shape changes in obesity monitoring using image processing techniques. Sci Rep 2024; 14:24178. [PMID: 39406756 PMCID: PMC11480043 DOI: 10.1038/s41598-024-73270-6] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/23/2024] [Accepted: 09/16/2024] [Indexed: 10/19/2024] Open
Abstract
Body measurements are primarily made with a tape measure. In measurements taken with a tape measure, the inability to take measurements from the same part of the body each time, incorrect positioning of the tape measure, the occurrence of incorrect measurements, and the need for a person to take the measurements are significant problems in the traditional measurement method. Due to the social distancing rule that must be followed during the Covid-19 pandemic, the close contact between the person to be measured and the person taking the measurement became the starting point of this study. This study focuses on the detecting body shape changes using image processing techniques with 2D imaging. The novelty of the work is that non-contact body measurements are taken more accurately and reliably using the cosine theorem. Regular monitoring of obese patients is important in combating obesity, which is also the source of many health problems. In the monitoring of obese patients, it is necessary to determine the rate of slimming in areas where fat accumulation is intense. The error margin between the real measurements of human models and the calculated measurements was calculated as an average of ± 5.16% for waistline and an average of ± 4.58% for hip size. The cosine theorem was used instead of the ellipse formula used in the literature, and it was observed that the cosine theorem obtained results closer to reality. It is also thought that the developed system will be beneficial not only for extracting body measurements but also for extracting body measurements contactless in the textile sector. The study demonstrates the feasibility of image processing for non-contact body anthropometry and shape tracking.
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Affiliation(s)
- Uçman Ergün
- Engineering Faculty, Biomedical Engineering Department , Afyon Kocatepe University, 03200, Afyonkarahisar, Turkey
| | - Elif Aktepe
- Afyon Vocational School, Electronics and Automation Department , Afyon Kocatepe University, 03200, Afyonkarahisar, Turkey
| | - Yavuz Bahadır Koca
- Engineering Faculty, Electrical Engineering Department, Afyon Kocatepe University, 03200, Afyonkarahisar, Turkey.
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Gualdi-Russo E, Masotti S, Rinaldo N, De Luca F, Toselli S, Mazzoni G, Mandini S, Zaccagni L. A Longitudinal Study on Body Image Perception and Size among Italian Early Adolescents: Changes over Time and Discrepancies between Genders. Nutrients 2024; 16:3439. [PMID: 39458435 PMCID: PMC11510257 DOI: 10.3390/nu16203439] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/24/2024] [Revised: 10/03/2024] [Accepted: 10/08/2024] [Indexed: 10/28/2024] Open
Abstract
BACKGROUND/OBJECTIVES The discrepancy between the current perceived body image (BI) and beauty ideals leads to dissatisfaction, which is believed to be common among adolescents. This study aimed to investigate the stability in BI perceptions and dissatisfaction during early adolescence. Another aim was to highlight differences in dissatisfaction according to Body Mass Index (BMI) and inconsistencies in weight status perception. METHODS Two hundred and nine participants (mean age at first survey: 11.33 ± 0.38 years) were enrolled in this longitudinal study with three years of follow-up. Data on size and BI perceptions were collected through individual interviews. Stature and weight were directly measured. RESULTS Findings indicated significant changes over three years in anthropometric traits but not in weight status prevalence or BI perception and dissatisfaction, except for the ideal figure in males and weight control in females. The results also indicated a significant difference in BI perception and dissatisfaction by BMI categories. Self-reported body measurements were found to be unreliable with a weak-to-moderate agreement between self-perceived and actual weight status. CONCLUSIONS BI perception appears quite stable across the three years considered. Dissatisfaction is similar in both genders, although a tendency toward different gender aesthetic ideals is already appreciable in early adolescence. We suggest that the lower frequency of normal-weight adolescents compared with peers in previous studies is attributable to the effects of the recent pandemic. Given the growing dissatisfaction with increasing BMI and misinterpretations of weight status, school actions to promote a healthy lifestyle and positive BI should be undertaken.
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Affiliation(s)
- Emanuela Gualdi-Russo
- Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, 44121 Ferrara, Italy; (N.R.); (F.D.L.); (G.M.); (S.M.); (L.Z.)
| | - Sabrina Masotti
- Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, 44121 Ferrara, Italy; (N.R.); (F.D.L.); (G.M.); (S.M.); (L.Z.)
- Center for Exercise Science and Sports, University of Ferrara, 44123 Ferrara, Italy
| | - Natascia Rinaldo
- Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, 44121 Ferrara, Italy; (N.R.); (F.D.L.); (G.M.); (S.M.); (L.Z.)
- Center for Exercise Science and Sports, University of Ferrara, 44123 Ferrara, Italy
| | - Federica De Luca
- Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, 44121 Ferrara, Italy; (N.R.); (F.D.L.); (G.M.); (S.M.); (L.Z.)
| | - Stefania Toselli
- Department for Life Quality Studies, University of Bologna, 47921 Rimini, Italy;
| | - Gianni Mazzoni
- Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, 44121 Ferrara, Italy; (N.R.); (F.D.L.); (G.M.); (S.M.); (L.Z.)
- Center for Exercise Science and Sports, University of Ferrara, 44123 Ferrara, Italy
| | - Simona Mandini
- Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, 44121 Ferrara, Italy; (N.R.); (F.D.L.); (G.M.); (S.M.); (L.Z.)
- Center for Exercise Science and Sports, University of Ferrara, 44123 Ferrara, Italy
| | - Luciana Zaccagni
- Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, 44121 Ferrara, Italy; (N.R.); (F.D.L.); (G.M.); (S.M.); (L.Z.)
- Center for Exercise Science and Sports, University of Ferrara, 44123 Ferrara, Italy
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Hunt ET, Brazendale K, De Moraes AC, Malkani R, Heredia NI, Pfledderer CD, Brown DM, Hoelscher DM, Beets MW, Weaver RG. Physical Activity and Sedentary Time Among U.S. Adolescents Before and During COVID-19: Findings From a Large Cohort Study. AJPM FOCUS 2024; 3:100253. [PMID: 39175501 PMCID: PMC11340494 DOI: 10.1016/j.focus.2024.100253] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Indexed: 08/24/2024]
Abstract
Introduction Evidence suggests that adolescents engage in less physical activity during the summer break. Less is known regarding physical activity during the summer months of the COVID-19 pandemic. Methods Utilizing data from the Adolescent Brain Cognitive Development study, the authors examined daily activity measured by Fitbit Charge 2 devices before and after the onset of the COVID-19 pandemic during school and summer months. Linear models estimated activity during pre-COVID-19 school, pre-COVID-19 summer, COVID-19 school, and COVID-19 summer. Results Participants (N=7,179, aged 11.96 years, 51% female, 51% White) accumulated 8,671.0 (95% CI=8,544.7; 8,797.3) steps, 32.5 (95% CI=30.8, 32.3) minutes of moderate-to-vigorous physical activity, and 507.2 (95% CI=504.2, 510.2) minutes of sedentary time. During COVID-19 school, adolescents accumulated fewer daily steps and minutes of moderate-to-vigorous physical activity (-1,782.3 steps [95% CI= -2,052.7; -1,511.8] and -6.2 minutes [95% CI= -8.4, -4.0], respectively). Adolescents accumulated more minutes of daily sedentary time (29.6 minutes [95% CI=18.9, 40.3]) during COVID-19 school months than during the pre-COVID-19 school months. During pre-COVID-19 summer months, adolescents accumulated 1,255.1 (95% CI=745.3; 1,765.0) more daily steps than during COVID-19 months. Boys accumulated more daily steps and moderate-to-vigorous physical activity (2,011.5 steps [95% CI=1,271.9; 2,751.0] and 7.9 minutes [95% CI=1.4, 14.4], respectively) during the summer before COVID-19 than in summer during COVID-19. Both girls and boys accumulated more minutes of sedentary time during COVID-19 school months (47.4 [95% CI=27.5, 67.3] and 51.2 [95% CI=22.8, 79.7], respectively) than during COVID-19 summer months. Conclusions Societal restrictions during COVID-19 negatively impacted activity levels in the U.S., particularly during the summer months during COVID-19.
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Affiliation(s)
- Ethan T. Hunt
- Michael and Susan Dell Center for Healthy Living, University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Austin, Texas
- Department of Health Promotion and Behavioral Science, University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Austin, Texas
| | - Keith Brazendale
- Department of Health Sciences, UCF College of Health Professions and Sciences, University of Central Florida, Orlando, Florida
| | - Augusto C.F. De Moraes
- Michael and Susan Dell Center for Healthy Living, University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Austin, Texas
- Department of Epidemiology, Human Genetics and Environmental Science, University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Austin, Texas
| | - Raja Malkani
- Michael and Susan Dell Center for Healthy Living, University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Austin, Texas
| | - Natalia I. Heredia
- Department of Health Promotion and Behavioral Science, University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Austin, Texas
| | - Christopher D. Pfledderer
- Michael and Susan Dell Center for Healthy Living, University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Austin, Texas
- Department of Health Promotion and Behavioral Science, University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Austin, Texas
| | - Denver M. Brown
- Department of Psychology, The University of Texas at San Antonio, San Antonio, Texas
| | - Deanna M. Hoelscher
- Michael and Susan Dell Center for Healthy Living, University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Austin, Texas
- Department of Health Promotion and Behavioral Science, University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Austin, Texas
| | - Michael W. Beets
- Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina
| | - Robert G. Weaver
- Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina
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Lister NB, Baur LA, House ET, Alexander S, Brown J, Collins CE, Cowell CT, Day K, Garnett SP, Gow ML, Grunseit AM, Henderson M, Inkster MK, Kwok C, Lang S, Paxton SJ, Truby H, Varady KA, Jebeile H. Intermittent Energy Restriction for Adolescents With Obesity: The Fast Track to Health Randomized Clinical Trial. JAMA Pediatr 2024; 178:1006-1016. [PMID: 39186288 PMCID: PMC11348084 DOI: 10.1001/jamapediatrics.2024.2869] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 05/02/2024] [Accepted: 06/13/2024] [Indexed: 08/27/2024]
Abstract
Importance Adolescent obesity requires effective and accessible treatment. Intensive dietary interventions have the potential to be used as adjunctive therapy for behavioral weight management. Objective To examine the effectiveness of 2 diet therapies, delivered as part of an intensive behavioral weight management intervention, in adolescents with metabolic complications associated with obesity. Design, Setting, and Participants This multisite, 52-week randomized clinical trial was conducted from January 31, 2018, to March 31, 2023, at 2 tertiary pediatric centers in Australia. Adolescents (aged 13-17 years) with obesity and 1 or more associated complications were included. Interventions Intensive behavioral interventions, delivered by a multidisciplinary team, comparing intermittent energy restriction (IER) or continuous energy restriction (CER), with 3 phases: very low-energy diet (weeks 0-4), intensive intervention (weeks 5-16), and continued intervention and/or maintenance (weeks 17-52). Main Outcomes and Measures The primary outcome was body mass index (BMI) z score at 52 weeks in the IER vs CER group. Anthropometry, body composition, and cardiometabolic health were assessed at baseline and 52 weeks. The BMI z score and percentiles were determined using Centers for Disease Control and Prevention growth charts. Insulin resistance, dyslipidemia, and elevated hepatic function were assessed. Results A total of 141 adolescents (median [IQR] age, 14.8 [12.9-17.9] years; 71 male [50.4%]) were enrolled, 71 in the IER group and 70 in the CER group, and 97 (68.8%) completed the intervention, 43 in the IER group and 54 in the CER group. At week 52, both groups had reduced BMI z scores (estimated marginal mean change, -0.28 [95% CI, -0.37 to -0.20] for IER and -0.28 [95% CI, -0.36 to -0.20] for CER) and reduced BMI expressed as a percentage of the 95th percentile (estimated marginal mean change, -9.56 [95% CI, -12.36 to -6.83] for IER and -9.23 [95% CI, -11.82 to -6.64] for CER). No differences were found in body composition or cardiometabolic outcomes between the groups. Both groups had a reduction in the occurrence of insulin resistance (from 52 of 68 [76.5%] to 32 of 56 [57.1%] in the IER group and from 59 of 68 [86.8%] to 31 of 60 [57.1%] in the CER group) at week 16; however, at week 52, this effect was observed in the CER group only (from 59 of 68 [86.7%] to 30 of 49 [61.2%]). The occurrence of dyslipidemia was unchanged between baseline and week 52 (60 of 137 [42.6%] and 37 of 87 [42.5%], respectively), with a small improvement in occurrence of impaired hepatic function tests (37 of 139 [27.0%] and 15 of 87 [17.2%], respectively). No differences were found in dyslipidemia or hepatic function between groups. Conclusions and Relevance These findings suggest that for adolescents with obesity-associated complications, IER can be incorporated into a behavioral weight management program, providing an option in addition to CER and offering participants more choice. Trial Registration http://anzctr.org.au Identifier: ACTRN12617001630303.
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Affiliation(s)
- Natalie B. Lister
- Faculty of Medicine and Health, Sydney Medical School, The University of Sydney, Westmead, New South Wales, Australia
- Institute of Endocrinology and Diabetes, The Children’s Hospital at Westmead, Westmead, New South Wales, Australia
| | - Louise A. Baur
- Faculty of Medicine and Health, Sydney Medical School, The University of Sydney, Westmead, New South Wales, Australia
- Weight Management Services, The Children’s Hospital at Westmead, Westmead, New South Wales, Australia
| | - Eve T. House
- Faculty of Medicine and Health, Sydney Medical School, The University of Sydney, Westmead, New South Wales, Australia
- Institute of Endocrinology and Diabetes, The Children’s Hospital at Westmead, Westmead, New South Wales, Australia
| | - Shirley Alexander
- Weight Management Services, The Children’s Hospital at Westmead, Westmead, New South Wales, Australia
| | - Justin Brown
- Department of Paediatric Endocrinology and Diabetes, Monash Children’s Hospital, Clayton, Victoria, Australia
- Department of Paediatrics, Monash University, Clayton, Victoria, Australia
| | - Clare E. Collins
- School of Health Sciences, College of Health, Medicine and Wellbeing, The University of Newcastle, Callaghan, New South Wales, Australia
- Food and Nutrition Research Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia
| | - Christopher T. Cowell
- Faculty of Medicine and Health, Sydney Medical School, The University of Sydney, Westmead, New South Wales, Australia
- Kids Research, The Children’s Hospital at Westmead, Westmead, New South Wales, Australia
| | - Kaitlin Day
- School of Agriculture, Food and Ecosystem Sciences, The University of Melbourne, Melbourne, Victoria, Australia
- Department of Nutrition, Dietetics & Food, Monash University, Melbourne, Victoria, Australia
| | - Sarah P. Garnett
- Faculty of Medicine and Health, Sydney Medical School, The University of Sydney, Westmead, New South Wales, Australia
- Kids Research, The Children’s Hospital at Westmead, Westmead, New South Wales, Australia
| | - Megan L. Gow
- Faculty of Medicine and Health, Sydney Medical School, The University of Sydney, Westmead, New South Wales, Australia
| | - Alicia M. Grunseit
- Department of Nutrition and Dietetics, The Children’s Hospital at Westmead, Westmead, New South Wales, Australia
| | - Maddison Henderson
- Institute of Endocrinology and Diabetes, The Children’s Hospital at Westmead, Westmead, New South Wales, Australia
| | - Mary-Kate Inkster
- Department of Paediatric Endocrinology and Diabetes, Monash Children’s Hospital, Clayton, Victoria, Australia
- Department of Nutrition, Dietetics & Food, Monash University, Melbourne, Victoria, Australia
| | - Cathy Kwok
- Faculty of Medicine and Health, Sydney Medical School, The University of Sydney, Westmead, New South Wales, Australia
- Weight Management Services, The Children’s Hospital at Westmead, Westmead, New South Wales, Australia
| | - Sarah Lang
- Department of Nutrition, Dietetics & Food, Monash University, Melbourne, Victoria, Australia
| | - Susan J. Paxton
- School of Psychology and Public Health, La Trobe University, Melbourne, Victoria, Australia
| | - Helen Truby
- School of Primary and Allied Health Care, Monash University, Victoria, Australia
- School of Human Movement and Nutrition Sciences, University of Queensland, Queensland, Australia
| | - Krista A. Varady
- Department of Kinesiology and Nutrition, University of Illinois, Chicago
| | - Hiba Jebeile
- Faculty of Medicine and Health, Sydney Medical School, The University of Sydney, Westmead, New South Wales, Australia
- Institute of Endocrinology and Diabetes, The Children’s Hospital at Westmead, Westmead, New South Wales, Australia
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Artymiak P, Żegleń M, Kryst Ł. The effect of the COVID-19 pandemic lockdown on the distribution of fat tissue and skinfold thickness in adolescents from Kraków (Poland). Pediatr Obes 2024; 19:e13160. [PMID: 39128856 DOI: 10.1111/ijpo.13160] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 02/13/2024] [Revised: 07/21/2024] [Accepted: 07/29/2024] [Indexed: 08/13/2024]
Abstract
BACKGROUND The COVID-19 pandemic has significantly changed the lifestyle and dietary habits of societies worldwide. The aim of the study was to assess changes in the distribution of fat tissue and skinfold thickness in adolescents (aged 11-15) from Kraków during the COVID-19 pandemic period. METHODS Two cross-sectional studies conducted in 2020 and 2022 (before and after the pandemic) involved 1662 adolescents from the Kraków population. Skinfold thickness measurements were taken. The trunk adiposity index, limbs-to-trunk fat ratio and limbs-to-total skinfold ratio were calculated. Statistical analysis employed a two-way ANOVA, Tukey's HSD test and the Kruskal-Wallis test, depending on the normality of the distribution. RESULTS Higher skinfold thicknesses were observed in the majority of age groups in both sexes from the 2022 cohort in comparison with the 2020 cohort. Additionally, higher values of the trunk adiposity index and the limbs-to-total skinfold ratio in most age groups were observed. However, an inverse trend was observed in the limbs-to-trunk fat radio. CONCLUSIONS The introduced restrictions such as lockdown, remote learning, reduced physical activity and changes in dietary habits could have influenced the distribution of fat tissue and skinfold thickness amongst adolescents from Kraków.
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Affiliation(s)
- Paulina Artymiak
- Department of Anthropology, Faculty of Physical Education and Sport, University of Physical Education, Kraków, Poland
| | - Magdalena Żegleń
- Pain Research Group, Institute of Psychology, Jagiellonian University, Kraków, Poland
| | - Łukasz Kryst
- Department of Anthropology, Faculty of Physical Education and Sport, University of Physical Education, Kraków, Poland
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Stankute I, Dulskiene V, Kuciene R. Associations between Changes in Body Weight Status and High Blood Pressure among Lithuanian Children and Adolescents during the COVID-19 Pandemic: A Retrospective Cohort Study. Nutrients 2024; 16:3256. [PMID: 39408222 PMCID: PMC11479103 DOI: 10.3390/nu16193256] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/13/2024] [Revised: 09/17/2024] [Accepted: 09/24/2024] [Indexed: 10/20/2024] Open
Abstract
(1) Background: High blood pressure (HBP), overweight, and obesity are common, growing public health problems worldwide. The aim of this study was to evaluate associations between changes in body weight status and HBP among Lithuanian children and adolescents during the COVID-19 pandemic. (2) Methods: In this study, we analysed data on blood pressure and anthropometric measurements of 2430 children and adolescents aged 8-18 years, who participated in both the baseline study conducted before the COVID-19 pandemic (from November 2019 to March 2020) and the follow-up study during the COVID-19 pandemic (from November 2021 to April 2022). Multivariate logistic regression analysis was used to estimate the associations between changes in weight status categories and HBP. (3) Results: At baseline, 17.1% of the subjects had overweight, 5.9% had obesity, 5.6% had abdominal obesity, and 23.7% had HBP, whereas at the follow-up, these percentages increased to 20.1%, 8.2%, 6.8%, and 27.4%, respectively. Compared to schoolchildren who maintained normal weight from baseline to the follow-up period, subjects who newly developed overweight/obesity and those who remained with persistent overweight/obesity had increased odds of HBP, with adjusted odds ratios (aORs) of 1.95 (p < 0.001) and 2.58 (p < 0.001), respectively. In subjects who transitioned from overweight/obesity to normal weight, the odds of HBP were slightly increased, with an aOR of 1.14 (p = 0.598), but the change was not statistically significant (p > 0.05). (4) Conclusions: This study observed an increase in the prevalence of overweight, obesity, and HBP among schoolchildren during the COVID-19 pandemic. The study also suggested that changes from normal body weight status at baseline to overweight/obesity during follow-up, especially persistent overweight/obesity, were associated with higher odds of HBP in Lithuanian children and adolescents during the COVID-19 pandemic.
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Affiliation(s)
- Ieva Stankute
- Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Sukileliu 15, LT-50162 Kaunas, Lithuania; (V.D.); (R.K.)
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Deng R, Chen W, Zhang Z, Zhang J, Wang Y, Sun B, Yin K, Cao J, Fan X, Zhang Y, Liu H, Fang J, Song J, Yu B, Mi J, Li X. Association Between Visceral Obesity Index and Diabetes: A Systematic Review and Meta-analysis. J Clin Endocrinol Metab 2024; 109:2692-2707. [PMID: 38709677 PMCID: PMC11403314 DOI: 10.1210/clinem/dgae303] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 03/12/2024] [Revised: 04/14/2024] [Accepted: 05/01/2024] [Indexed: 05/08/2024]
Abstract
CONTENT The correlation between visceral obesity index (VAI) and diabetes and accuracy of early prediction of diabetes are still controversial. OBJECTIVE This study aims to review the relationship between high level of VAI and diabetes and early predictive value of diabetes. DATA SOURCES The databases of PubMed, Cochrane, Embase, and Web of Science were searched until October 17, 2023. STUDY SELECTION After adjusting for confounding factors, the original study on the association between VAI and diabetes was analyzed. DATA EXTRACTION We extracted odds ratio (OR) between VAI and diabetes management after controlling for mixed factors, and the sensitivity, specificity, and diagnostic 4-grid table for early prediction of diabetes. DATA SYNTHESIS Fifty-three studies comprising 595 946 participants were included. The findings of the meta-analysis elucidated that in cohort studies, a high VAI significantly increased the risk of diabetes mellitus in males (OR = 2.83 [95% CI, 2.30-3.49]) and females (OR = 3.32 [95% CI, 2.48-4.45]). The receiver operating characteristic, sensitivity, and specificity of VAI for early prediction of diabetes in males were 0.64 (95% CI, .62-.66), 0.57 (95% CI, .53-.61), and 0.65 (95% CI, .61-.69), respectively, and 0.67 (95% CI, .65-.69), 0.66 (95% CI, .60-.71), and 0.61 (95% CI, .57-.66) in females, respectively. CONCLUSION VAI is an independent predictor of the risk of diabetes, yet its predictive accuracy remains limited. In future studies, determine whether VAI can be used in conjunction with other related indicators to early predict the risk of diabetes, to enhance the accuracy of prediction of the risk of diabetes.
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Affiliation(s)
- Ruixue Deng
- College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
| | - Weijie Chen
- College of Traditional Chinese Medicine, The First Affiliated Hospital of Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
| | - Zepeng Zhang
- Research Center of Traditional Chinese Medicine, College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
| | - Jingzhou Zhang
- College of Traditional Chinese Medicine, The First Affiliated Hospital of Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
| | - Ying Wang
- College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
| | - Baichuan Sun
- College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
| | - Kai Yin
- College of Integrated Chinese and Western Medicine, Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
| | - Jingsi Cao
- College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
| | - Xuechun Fan
- College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
| | - Yuan Zhang
- College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
| | - Huan Liu
- College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
| | - Jinxu Fang
- College of Acupuncture and Moxibustion Massage, Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
| | - Jiamei Song
- College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
| | - Bin Yu
- College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
| | - Jia Mi
- Department of Endocrinology, The First Affiliated Hospital of Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
| | - Xiangyan Li
- Northeast Asia Research Institute of Traditional Chinese Medicine, Key Laboratory of Active Substances and Biological Mechanisms of Ginseng Efficacy, Ministry of Education, Jilin Provincial Key Laboratory of Bio-Macromolecules of Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130117, Jilin, China
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Falbová D, Beňuš R, Sulis S, Vorobeľová L. Effect of COVID-19 pandemic on bioimpedance health indicators in young adults. Am J Hum Biol 2024; 36:e24110. [PMID: 38808377 DOI: 10.1002/ajhb.24110] [Citation(s) in RCA: 3] [Impact Index Per Article: 3.0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/25/2024] [Revised: 05/16/2024] [Accepted: 05/18/2024] [Indexed: 05/30/2024] Open
Abstract
OBJECTIVES Herein, we investigate the relationships between the COVID-19 pandemic and overcoming the virus, and its effects on body composition parameters in young adults from Slovakia. METHODS We assessed 773 adults aged 18 to 30 years in pandemic-status sub-groups. Individual lifestyles and overcoming the COVID-19 effects were evaluated by a detailed questionnaire, and body composition parameters were analyzed using the InBody 770 bioimpedance analyzer. RESULTS Statistically significant lower values were observed in the male group during the pandemic for the following parameters; proteins and minerals, fat free mass (FFM), skeletal muscle mass (SMM), lean body mass (LBM) and its values in the right and left arm and trunk, total body water (TBW) and its values in the right and left arm and trunk, body cell mass (BCM), basal metabolic rate (BMR) and phase angle (PA). The regression analysis confirmed the negative pandemic effect and the negative impact of COVID-19 on men in the following parameters: proteins (p = .027 for pandemic and p = .005 for COVID-19), FFM (p = .023 for pandemic and p = .005 for COVID-19), LBM (p = .022 for pandemic and p = .004 for COVID-19), SMM (p = .028 for pandemic and p = .005 for COVID-19), TBW (p = .020 for pandemic and p = .004 for COVID-19), BMR (p = .024 for pandemic and p = .005 for COVID-19) and PA (p = .009 for pandemic). Physical activity was a further significant predictor in men for all the above parameters. CONCLUSIONS We observed significantly lower body composition parameters associated with fat free mass in young adult men during the pandemic than before it. However, future research is warranted to determine if these effects have long-term significance.
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Affiliation(s)
- Darina Falbová
- Department of Anthropology, Faculty of Natural Sciences, Comenius University in Bratislava, Bratislava, Slovakia
| | - Radoslav Beňuš
- Department of Anthropology, Faculty of Natural Sciences, Comenius University in Bratislava, Bratislava, Slovakia
| | - Simona Sulis
- Department of Anthropology, Faculty of Natural Sciences, Comenius University in Bratislava, Bratislava, Slovakia
| | - Lenka Vorobeľová
- Department of Anthropology, Faculty of Natural Sciences, Comenius University in Bratislava, Bratislava, Slovakia
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Basuodan RM, Gmmash A, Alghadier M, Albesher RA. Relationship between Pain, Physical Activity, Screen Time and Age among Young Children during the COVID-19 Pandemic. Healthcare (Basel) 2024; 12:1635. [PMID: 39201193 PMCID: PMC11353332 DOI: 10.3390/healthcare12161635] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/18/2024] [Revised: 08/12/2024] [Accepted: 08/14/2024] [Indexed: 09/02/2024] Open
Abstract
INTRODUCTION During the COVID-19 pandemic, many countries implemented restrictions, social distancing measures, and lockdowns to limit the spread of the disease. These lockdowns have affected children's screen time (ST), pain, and physical activity (PA) levels. The present study aimed to explore the relationships between ST, pain, age, and PA before, during, and after the COVID-19 pandemic. METHODS The caregivers of 329 children (median age = 8 years) filled out an online self-reported survey about the children's PA, ST, and pain before, during, and after the COVID-19 curfew. Spearman's rank correlation coefficient was used to explore the associations between these variables. RESULTS After the curfew, pain that existed before the pandemic had a weak negative relationship with PA intensity (-0.11, p = 0.04) and a weak positive relationship with ST (r = +0.12, p = 0.04). There was a strong positive relationship between ST in all time periods (p > 0.01). PA and ST had a weak negative relationship (p > 0.05) during the curfew and after the curfew but not before the COVID-19 pandemic. Age had a weak positive correlation with ST in all time periods (p > 0.01). In addition, ST was affected by the curfew. CONCLUSION The study findings indicated that young children had longer ST during the curfew and after the curfew compared with before the curfew. Increasing PA could lessen children's ST, which could, in turn, increase the probability that their general pain would decrease.
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Affiliation(s)
- Reem M. Basuodan
- Department of Rehabilitation Science, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia;
| | - Afnan Gmmash
- Department of Physical Therapy, King Abdulaziz University, Jeddah 21589, Saudi Arabia;
| | - Mshari Alghadier
- Department of Physical Therapy and Rehabilitation, Prince Sattam bin Abdulaziz University, Alkharj 16278, Saudi Arabia;
| | - Reem A. Albesher
- Department of Rehabilitation Science, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia;
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Petimar J, Young JG, Yu H, Rifas-Shiman SL, Daley MF, Heerman WJ, Janicke DM, Jones WS, Lewis KH, Lin PID, Prentice C, Merriman JW, Toh S, Block JP. Medication-Induced Weight Change Across Common Antidepressant Treatments : A Target Trial Emulation Study. Ann Intern Med 2024; 177:993-1003. [PMID: 38950403 PMCID: PMC11819980 DOI: 10.7326/m23-2742] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 07/03/2024] Open
Abstract
BACKGROUND Antidepressants are among the most commonly prescribed medications, but evidence on comparative weight change for specific first-line treatments is limited. OBJECTIVE To compare weight change across common first-line antidepressant treatments by emulating a target trial. DESIGN Observational cohort study over 24 months. SETTING Electronic health record (EHR) data from 2010 to 2019 across 8 U.S. health systems. PARTICIPANTS 183 118 patients. MEASUREMENTS Prescription data determined initiation of treatment with sertraline, citalopram, escitalopram, fluoxetine, paroxetine, bupropion, duloxetine, or venlafaxine. The investigators estimated the population-level effects of initiating each treatment, relative to sertraline, on mean weight change (primary) and the probability of gaining at least 5% of baseline weight (secondary) 6 months after initiation. Inverse probability weighting of repeated outcome marginal structural models was used to account for baseline confounding and informative outcome measurement. In secondary analyses, the effects of initiating and adhering to each treatment protocol were estimated. RESULTS Compared with that for sertraline, estimated 6-month weight gain was higher for escitalopram (difference, 0.41 kg [95% CI, 0.31 to 0.52 kg]), paroxetine (difference, 0.37 kg [CI, 0.20 to 0.54 kg]), duloxetine (difference, 0.34 kg [CI, 0.22 to 0.44 kg]), venlafaxine (difference, 0.17 kg [CI, 0.03 to 0.31 kg]), and citalopram (difference, 0.12 kg [CI, 0.02 to 0.23 kg]); similar for fluoxetine (difference, -0.07 kg [CI, -0.19 to 0.04 kg]); and lower for bupropion (difference, -0.22 kg [CI, -0.33 to -0.12 kg]). Escitalopram, paroxetine, and duloxetine were associated with 10% to 15% higher risk for gaining at least 5% of baseline weight, whereas bupropion was associated with 15% reduced risk. When the effects of initiation and adherence were estimated, associations were stronger but had wider CIs. Six-month adherence ranged from 28% (duloxetine) to 41% (bupropion). LIMITATION No data on medication dispensing, low medication adherence, incomplete data on adherence, and incomplete data on weight measures across time points. CONCLUSION Small differences in mean weight change were found between 8 first-line antidepressants, with bupropion consistently showing the least weight gain, although adherence to medications over follow-up was low. Clinicians could consider potential weight gain when initiating antidepressant treatment. PRIMARY FUNDING SOURCE National Institutes of Health.
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Affiliation(s)
- Joshua Petimar
- Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, and Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts (J.P., J.G.Y.)
| | - Jessica G Young
- Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, and Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts (J.P., J.G.Y.)
| | - Han Yu
- Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts (H.Y., S.L.R.-S., P.-I.D.L., S.T., J.P.B.)
| | - Sheryl L Rifas-Shiman
- Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts (H.Y., S.L.R.-S., P.-I.D.L., S.T., J.P.B.)
| | - Matthew F Daley
- Institute for Health Research, Kaiser Permanente Colorado, Denver, Colorado (M.F.D.)
| | - William J Heerman
- Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee (W.J.H.)
| | - David M Janicke
- Department of Clinical and Health Psychology, College of Public Health and Health Professions, University of Florida, Gainesville, Florida (D.M.J.)
| | - W Schuyler Jones
- Division of Cardiology, Duke University Department of Medicine, and Duke University Medical Center, Duke Clinical Research Institute, Durham, North Carolina (W.S.J.)
| | - Kristina H Lewis
- Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina (K.H.L.)
| | - Pi-I D Lin
- Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts (H.Y., S.L.R.-S., P.-I.D.L., S.T., J.P.B.)
| | - Carly Prentice
- Faith Family Medical Center, Nashville, Tennessee (C.P.)
| | - John W Merriman
- Department of Medicine, College of Medicine, University of Florida, Gainesville, Florida (J.W.M.)
| | - Sengwee Toh
- Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts (H.Y., S.L.R.-S., P.-I.D.L., S.T., J.P.B.)
| | - Jason P Block
- Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts (H.Y., S.L.R.-S., P.-I.D.L., S.T., J.P.B.)
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Macdonald GA, Thomas JA, Dalais C, Kendall BJ, Thrift AP. Joint association of drinking alcohol and obesity in relation to cancer risk: A systematic review and data synthesis. Cancer Epidemiol 2024; 91:102596. [PMID: 38870623 DOI: 10.1016/j.canep.2024.102596] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/13/2023] [Revised: 04/28/2024] [Accepted: 05/27/2024] [Indexed: 06/15/2024]
Abstract
BACKGROUND Rates of alcohol consumption and obesity are increasing in many Western populations. For some cancer types, both heavy alcohol consumption and obesity are independently associated with increased risk. Whether combined exposure to both synergistically increases an individual's risk of cancer is unclear. We performed a systematic review to assess whether alcohol and obesity interact to confer higher risk for cancer than the additive sum of their effects. METHODS A systematic literature search was conducted from the inception date to 13 February 2024 of PubMed, Embase, Cochrane Library and Web of Science to identify studies of alcohol, obesity, and cancer risk. We aimed to undertake a meta-analysis if there were sufficient data. RESULTS The literature search identified 17,740 potentially eligible studies. After review, 24 studies were included. Eleven reported on the association between alcohol consumption and cancer risk in individuals according to their body mass index (BMI), nine reported on the association between BMI and cancer risk in individuals according to their alcohol consumption, and six studies examined potential synergistic interactions between alcohol consumption and obesity on cancer risk. However, there were insufficient data and significant heterogeneity in the cancers studied to undertake meta-analysis, therefore a systemic review and narrative synthesis was conducted. Overall, there was no consistent pattern of interaction between alcohol use and overweight/obesity on cancer risk across cancer types. CONCLUSIONS While alcohol and obesity are prevalent and important risk factors for a range of cancers, data are lacking on whether their combined exposure may synergistically increase an individual's risk for cancer. Further study across more cancer types is required to better understand the nature of interactions between alcohol use and obesity on cancer risk.
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Affiliation(s)
- Graeme A Macdonald
- Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia; Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, QLD, Australia
| | - James A Thomas
- Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia; Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, QLD, Australia
| | - Christine Dalais
- University of Queensland Library, University of Queensland, Brisbane, QLD, Australia
| | - Bradley J Kendall
- Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia; Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, QLD, Australia
| | - Aaron P Thrift
- Section of Epidemiology and Population Sciences, Department of Medicine, Baylor College of Medicine, Houston, TX, USA; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA.
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Nicze M, Dec A, Borówka M, Krzyżak D, Bołdys A, Bułdak Ł, Okopień B. Molecular Mechanisms behind Obesity and Their Potential Exploitation in Current and Future Therapy. Int J Mol Sci 2024; 25:8202. [PMID: 39125772 PMCID: PMC11311839 DOI: 10.3390/ijms25158202] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/28/2024] [Revised: 07/22/2024] [Accepted: 07/25/2024] [Indexed: 08/12/2024] Open
Abstract
Obesity is a chronic disease caused primarily by the imbalance between the amount of calories supplied to the body and energy expenditure. Not only does it deteriorate the quality of life, but most importantly it increases the risk of cardiovascular diseases and the development of type 2 diabetes mellitus, leading to reduced life expectancy. In this review, we would like to present the molecular pathomechanisms underlying obesity, which constitute the target points for the action of anti-obesity medications. These include the central nervous system, brain-gut-microbiome axis, gastrointestinal motility, and energy expenditure. A significant part of this article is dedicated to incretin-based drugs such as GLP-1 receptor agonists (e.g., liraglutide and semaglutide), as well as the brand new dual GLP-1 and GIP receptor agonist tirzepatide, all of which have become "block-buster" drugs due to their effectiveness in reducing body weight and beneficial effects on the patient's metabolic profile. Finally, this review article highlights newly designed molecules with the potential for future obesity management that are the subject of ongoing clinical trials.
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Affiliation(s)
- Michał Nicze
- Department of Internal Medicine and Clinical Pharmacology, Faculty of Medical Sciences, Medical University of Silesia in Katowice, Medyków 18, 40-752 Katowice, Poland (A.B.); (B.O.)
| | | | | | | | | | - Łukasz Bułdak
- Department of Internal Medicine and Clinical Pharmacology, Faculty of Medical Sciences, Medical University of Silesia in Katowice, Medyków 18, 40-752 Katowice, Poland (A.B.); (B.O.)
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Peres M, Moreira-Rosário A, Padeira G, Gaspar Silva P, Correia C, Nunes A, Garcia E, Faria A, Teixeira D, Calhau C, Pereira-da-Silva L, Ferreira AC, Rocha JC. Biochemical and Anthropometric Outcomes in Paediatric Patients with Heterozygous Familial Hypercholesterolemia after COVID-19 Pandemic Lockdowns: An Exploratory Analysis. Nutrients 2024; 16:2170. [PMID: 38999917 PMCID: PMC11242984 DOI: 10.3390/nu16132170] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/10/2024] [Revised: 07/03/2024] [Accepted: 07/03/2024] [Indexed: 07/14/2024] Open
Abstract
The COVID-19 pandemic lockdowns affected the lifestyles of children and adolescents, leading to an increase in childhood obesity. Paediatric patients with familial hypercholesterolemia (FH) may be more susceptible to lockdown effects due to their increased cardiovascular risk. However, data are lacking. We investigated the effect of lockdowns on the metabolic profile of paediatric patients with FH. Blood lipids and anthropometry measured in September 2021-April 2022 were retrospectively compared with pre-pandemic values. Thirty participants were included (1-16 years; 57% female). From baseline to post-pandemic, median [P25, P75] blood LDL-C concentration was 125 [112, 150] mg/dL vs. 125 [100, 147] mg/dL (p = 0.894); HDL-C was 58 [52, 65] mg/dL vs. 56 [51, 61] mg/dL (p = 0.107); triglycerides were 64 [44, 86] mg/dL vs. 59 [42, 86] mg/dL (p = 0.178). The BMI z-score did not change significantly (0.19 [-0.58, 0.89] vs. 0.30 [-0.48, 1.10], p = 0.524). The lack of deterioration in metabolic profiles during lockdowns is positive, as some deterioration was expected. We speculate that patients and caregivers were successfully educated about healthy lifestyle and dietary habits. Our results should be interpreted with caution since the study sample was small and heterogeneous. Multicentre research is needed to better understand the impact of lockdowns on this population.
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Affiliation(s)
- Maria Peres
- Nutrition and Metabolism, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal
| | - André Moreira-Rosário
- Nutrition and Metabolism, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal
- CHRC-Comprehensive Health Research Centre, Nutrition Group, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal
- CINTESIS-Center for Health Technology and Services Research, NOVA Medical School, 1169-056 Lisboa, Portugal
| | - Gonçalo Padeira
- Reference Centre of Inherited Metabolic Diseases, Unidade Local de Saúde São José, Centro Clínico Académico de Lisboa, 1169-045 Lisboa, Portugal
| | - Patrícia Gaspar Silva
- Reference Centre of Inherited Metabolic Diseases, Unidade Local de Saúde São José, Centro Clínico Académico de Lisboa, 1169-045 Lisboa, Portugal
| | - Carla Correia
- Reference Centre of Inherited Metabolic Diseases, Unidade Local de Saúde São José, Centro Clínico Académico de Lisboa, 1169-045 Lisboa, Portugal
| | - Andreia Nunes
- Reference Centre of Inherited Metabolic Diseases, Unidade Local de Saúde São José, Centro Clínico Académico de Lisboa, 1169-045 Lisboa, Portugal
| | - Elisabete Garcia
- Reference Centre of Inherited Metabolic Diseases, Unidade Local de Saúde São José, Centro Clínico Académico de Lisboa, 1169-045 Lisboa, Portugal
| | - Ana Faria
- Nutrition and Metabolism, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal
- CHRC-Comprehensive Health Research Centre, Nutrition Group, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal
| | - Diana Teixeira
- Nutrition and Metabolism, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal
- CHRC-Comprehensive Health Research Centre, Nutrition Group, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal
| | - Conceição Calhau
- Nutrition and Metabolism, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal
- CHRC-Comprehensive Health Research Centre, Nutrition Group, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal
- CINTESIS-Center for Health Technology and Services Research, NOVA Medical School, 1169-056 Lisboa, Portugal
| | - Luís Pereira-da-Silva
- CHRC-Comprehensive Health Research Centre, Nutrition Group, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal
- Medicine of Woman, Childhood and Adolescence Academic Area, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal
| | - Ana Cristina Ferreira
- Reference Centre of Inherited Metabolic Diseases, Unidade Local de Saúde São José, Centro Clínico Académico de Lisboa, 1169-045 Lisboa, Portugal
| | - Júlio César Rocha
- Nutrition and Metabolism, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal
- CHRC-Comprehensive Health Research Centre, Nutrition Group, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal
- CINTESIS-Center for Health Technology and Services Research, NOVA Medical School, 1169-056 Lisboa, Portugal
- Reference Centre of Inherited Metabolic Diseases, Unidade Local de Saúde São José, Centro Clínico Académico de Lisboa, 1169-045 Lisboa, Portugal
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Spiegler C, Jansen S, Burgard L, Wittig F, Brettschneider AK, Schlune A, Heuer T, Straßburg A, Roser S, Storcksdieck Genannt Bonsmann S, Ensenauer R. Unfavorable food consumption in children up to school entry age: results from the nationwide German KiESEL study. Front Nutr 2024; 11:1335934. [PMID: 39010856 PMCID: PMC11246898 DOI: 10.3389/fnut.2024.1335934] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/09/2023] [Accepted: 06/13/2024] [Indexed: 07/17/2024] Open
Abstract
Introduction Evidence points toward the early life being crucial for preventing nutrition-related diseases. As promotion of healthier food preferences in toddlerhood and preschool age might still modulate the trajectories of disease risk, understanding diet in these age groups is necessary. The objective was to analyze food consumption and diet quality of 1-5-year-old children living in Germany in relation to age and sex. Methods Data from 890 children, a subsample of the representative, cross-sectional Children's Nutrition Survey to Record Food Consumption (KiESEL) conducted by the German Federal Institute for Risk Assessment in 2014-2017, were analyzed. Dietary data were collected using food records (3 consecutive plus 1 independent day). Diet quality was evaluated against the German food-based dietary guidelines (FBDG). Results Consumption of unfavorable foods (e.g., sweets, soft drinks) exceeded the recommended maximum of 10% of energy intake (E%) by a multiple in all age and sex groups (medians: 24.8-35.8 E%). Preschoolers consumed more unfavorable foods than toddlers and boys more than girls. More than half of the children exceeded the recommendation for meat intake (medians: 2.3-3.2% of the total food consumption (%TFC) vs. 2 %TFC), especially preschoolers. In nearly all children, vegetable consumption was too low (medians: 4.2-4.5 %TFC vs. 12 %TFC). Also, milk/milk product consumption was below recommendations, more so in preschoolers (median: 12.0 %TFC ♂, 11.9 %TFC ♀ vs. 18 %TFC) than in toddlers (median: 16.1 %TFC ♂, 19.6 %TFC ♀). In toddlers and preschoolers with overweight or obesity, adherence to dietary recommendations of these food groups was largely similar to that of the total sample. Overall, 5-year-olds showed an unhealthier dietary pattern than 1-year-olds, which already emerged at age 2 years and became more evident at age 3 years. Discussion An adverse dietary pattern arises and even deteriorates at a very young age, showing sex-specific aspects. High attention from public health and research needs to be given to toddlerhood and even earlier life phases, e.g., to develop more age-specific FBDGs, aiming at reducing unhealthy food consumption.
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Affiliation(s)
- Clarissa Spiegler
- Department of Nutritional Behaviour, Max Rubner-Institut (MRI) – Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
| | - Sara Jansen
- Department of Child Nutrition, Max Rubner-Institut (MRI) – Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
| | - Leonie Burgard
- Department of Nutritional Behaviour, Max Rubner-Institut (MRI) – Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
| | - Friederike Wittig
- Department of Nutritional Behaviour, Max Rubner-Institut (MRI) – Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
| | - Anna-Kristin Brettschneider
- Department of Child Nutrition, Max Rubner-Institut (MRI) – Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
| | - Andrea Schlune
- Department of Child Nutrition, Max Rubner-Institut (MRI) – Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
| | - Thorsten Heuer
- Department of Nutritional Behaviour, Max Rubner-Institut (MRI) – Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
| | - Andrea Straßburg
- Department of Nutritional Behaviour, Max Rubner-Institut (MRI) – Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
| | - Silvia Roser
- Max Rubner-Institut (MRI) – Federal Research Institute of Nutrition and Food, Presidential Office, Karlsruhe, Germany
| | | | - Regina Ensenauer
- Department of Child Nutrition, Max Rubner-Institut (MRI) – Federal Research Institute of Nutrition and Food, Karlsruhe, Germany
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Zaccagni L, De Luca F, Rinaldo N, Mazzoni G, Mandini S, Gualdi-Russo E. The COVID-19 Experience in Adolescents: Emotional and Behavioral Recall at the End of the Pandemic. Diseases 2024; 12:116. [PMID: 38920548 PMCID: PMC11202612 DOI: 10.3390/diseases12060116] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/23/2024] [Revised: 05/24/2024] [Accepted: 05/30/2024] [Indexed: 06/27/2024] Open
Abstract
The COVID-19 pandemic and the resulting lockdown countermeasure may have significantly affected adolescents' physical and mental health. This study aims to assess adolescents' recollections of this period, also analyzing their current weight status along with factors they traced back to the epidemic phase and their current sports practice. A survey among 233 Italian adolescents aged 12.4 ± 0.9 years was conducted in October 2023. To achieve the research objectives, a new questionnaire was developed: the COVID-19 AdolesceNt/chilDren Lockdown Experience questionnaire (CANDLE). The new questionnaire was employed to gather data on the adolescents' recollections of the lockdown situation they experienced. The stature and weight of participants were measured directly. The results indicated that middle schoolers remember both positive and negative experiences of the lockdown: the change perceived as the most positive was spending more time with family, while social detachment from peers represents the most negative aspect. According to multivariate regression analysis, certain behaviors they assumed during the lockdown, such as comfort food consumption in boys and sleeping disturbances in girls, in addition to their current sports practice, affected their actual Body Mass Index. This study supports the evidence that changes caused by the COVID-19 lockdown affected adolescents' physical and mental health, albeit with sex differences.
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Affiliation(s)
- Luciana Zaccagni
- Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, Corso Ercole I d’Este 32, 44121 Ferrara, Italy; (L.Z.); (N.R.); (G.M.); (S.M.)
- Center for Exercise Science and Sports, University of Ferrara, 44123 Ferrara, Italy
| | - Federica De Luca
- Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, Corso Ercole I d’Este 32, 44121 Ferrara, Italy; (L.Z.); (N.R.); (G.M.); (S.M.)
| | - Natascia Rinaldo
- Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, Corso Ercole I d’Este 32, 44121 Ferrara, Italy; (L.Z.); (N.R.); (G.M.); (S.M.)
- Center for Exercise Science and Sports, University of Ferrara, 44123 Ferrara, Italy
| | - Gianni Mazzoni
- Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, Corso Ercole I d’Este 32, 44121 Ferrara, Italy; (L.Z.); (N.R.); (G.M.); (S.M.)
- Center for Exercise Science and Sports, University of Ferrara, 44123 Ferrara, Italy
| | - Simona Mandini
- Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, Corso Ercole I d’Este 32, 44121 Ferrara, Italy; (L.Z.); (N.R.); (G.M.); (S.M.)
- Center for Exercise Science and Sports, University of Ferrara, 44123 Ferrara, Italy
| | - Emanuela Gualdi-Russo
- Department of Neuroscience and Rehabilitation, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, Corso Ercole I d’Este 32, 44121 Ferrara, Italy; (L.Z.); (N.R.); (G.M.); (S.M.)
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Samigullin A, Groß G, Gählert J, Buchenberger S, Morcos M, Schwertz R, Öste R, Siegel E, Humpert P. Impact of Covid-19 lockdowns on the anthropometric development in primary school children in the Rhein-Neckar Region, Germany. BMC Nutr 2024; 10:78. [PMID: 38811974 PMCID: PMC11134761 DOI: 10.1186/s40795-024-00886-2] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/13/2023] [Accepted: 05/21/2024] [Indexed: 05/31/2024] Open
Abstract
BACKGROUND Published data suggests that lockdowns during the COVID-19 pandemic may have negatively affected children's weight development. This study aims to assess the prevalence of overweight and obesity after the COVID-19 lockdowns as well as anthropometric development among primary school children in the Rhein-Neckar Region, Germany. METHODS In this cross-sectional study, schools were selected in cooperation with the local health authority to include different socioeconomic backgrounds. Participation was voluntary at school and individual level, requiring written informed consent from legal guardians. Study visits in schools were conducted between October 2021 and July 2022. Anthropometric data from nationally recommended medical examinations at 4 years (U8) and 5 years (U9), data on nutrition, physical activity, and socioeconomic data was collected using questionnaires. zBMI and weight category were calculated based on German reference data. RESULTS 256 children with a mean age of 8.0 years (7.1-9.3 years) were included in the study. Most participants were from households with an above average income. 5.1% of the children were overweight, 4.7% were obese, 15.6% were underweight, and 74.6% were normal weight with a mean zBMI of -0.25 (SD 1.10), which is significantly lower than the mean zBMI of the German reference population (p < 0.001). No significant changes in zBMI were observed between U8 and U9 (p = 0.16). The mean zBMI decreased by 0.17 (SD 0.72) between U9 and the study visit (p = 0.02). A zBMI decrease of 0.5 was documented for the subgroup of overweight and obese children (p = 0.028) as well as a decrease of 0.23 (SD 0.63) for the normal-weight children subgroup (p < 0.001). CONCLUSIONS Contrary to previous reports mean zBMI decreased significantly in the children studied. No significant changes in zBMI were observed between U8 and U9 examinations, which supports the hypothesis that the decrease in zBMI could be attributed to lockdown measures. The study was registered at clinicaltrials.gov on September 21st 2021 under the registration number NCT05077059.
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Affiliation(s)
- Azat Samigullin
- Starscience GmbH, Heidelberg, Germany.
- Stoffwechselzentrum Rhein-Pfalz, Mannheim, Germany.
| | - Gabriel Groß
- Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
| | - Jana Gählert
- Medical Faculty Heidelberg, University of Heidelberg, Heidelberg, Germany
| | - Sandra Buchenberger
- Starscience GmbH, Heidelberg, Germany
- Stoffwechselzentrum Rhein-Pfalz, Mannheim, Germany
| | - Michael Morcos
- Stoffwechselzentrum Rhein-Pfalz, Mannheim, Germany
- Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
| | | | | | - Erhard Siegel
- St. Josefskrankenhaus, Heidelberg, Germany
- Adipositasnetzwerk Rhein-Neckar e. V., Heidelberg, Germany
| | - Per Humpert
- Stoffwechselzentrum Rhein-Pfalz, Mannheim, Germany
- Medical Faculty Heidelberg, University of Heidelberg, Heidelberg, Germany
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Katayama N, Yoshida T, Nakashima T, Kobayashi M, Suzuki H, Hamajima N, Sone M. Lifestyle habits and examination findings before and during the COVID-19 pandemic: From health checkups in a rural area in Japan. Nutr Health 2024:2601060241256201. [PMID: 38778709 DOI: 10.1177/02601060241256201] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 05/25/2024]
Abstract
Aim: Few health checkup studies have reported lifestyle habits and examination results before and during the COVID-19 pandemic. We compared lifestyle habits and examination results surveyed before and during the COVID-19 pandemic. Methods: Five hundred and ten and 396 participants attended the health checkup in 2019 and 2022, respectively. The median age of females was 65 in 2019 and 2022, and that of males was 68 in 2019 and 69 in 2022. We investigated dietary and exercise habits, alcohol consumption, sleeping situation, and examination results, including body mass index (BMI), smell function, and blood examination results before and during the COVID-19 pandemic in a rural area in Japan. Results: An ordinal logistic regression analysis revealed that the intake frequency of vegetables and marine products was significantly less in 2022 than in 2019 after adjusting age and sex; green leafy vegetables (p = .016), fish (p = .002), and other marine products, including squid, shrimp, crabs, and octopus (p = .008). Alcohol consumption amount increased significantly in 2022 than in 2019 in men who drank beer (p = .007) and chuhai (p = .040). Albumin, hematocrit, cholesterols, and uric acid decreased, but serum calcium increased significantly in 2022 than in 2019 after adjusting age and sex. BMI and hemoglobin A1c were not significantly different between 2019 and 2022. A decrease in subjective smell feeling and smell test results was associated with decreased intake frequency of vegetables. Conclusion: Both dietary habits and blood examination results changed significantly during the COVID-19 pandemic in a rural area in Japan.
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Affiliation(s)
- Naomi Katayama
- Department of Food Science, Nagoya Women's University, Nagoya, Japan
- Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan
| | - Tadao Yoshida
- Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan
| | - Tsutomu Nakashima
- Department of Rehabilitation, Ichinomiya Medical Treatment & Habilitation Center, Ichinomiya, Japan
- Department of Otorhinolaryngology, Center for Sensory Organ, National Center for Geriatrics and Gerontology, Obu, Japan
- Nagoya University, Nagoya Japan
| | - Masumi Kobayashi
- Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan
| | - Hirokazu Suzuki
- Department of Otorhinolaryngology, Center for Sensory Organ, National Center for Geriatrics and Gerontology, Obu, Japan
| | | | - Michihiko Sone
- Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan
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Schluter PJ, Ahuriri-Driscoll A, Mohammed J, Singh S. COVID-19 impact on overweight and obesity rates in Aotearoa | New Zealand 4-year-old children. Pediatr Res 2024; 95:1649-1657. [PMID: 38238565 PMCID: PMC11126386 DOI: 10.1038/s41390-024-03025-6] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 09/05/2023] [Revised: 12/07/2023] [Accepted: 12/15/2023] [Indexed: 05/26/2024]
Abstract
BACKGROUND COVID-19 has had profound societal impacts. This study estimated overweight, obesity, and extreme obesity rates in 4-year-old children over pre- and post-COVID-19 periods, and investigated differential changes between sex, ethnic and deprivation groups. METHODS A national screening programme of 4-year-old children undertaking B4 School Checks (B4SCs) between 1 January 2010 and 7 March 2023 was analysed. B4SCs include anthropometric measurements enabling sex-specific body mass index-for-age Z-scores (BMI z-scores) to be derived. Children with ≥85th, ≥95th, and ≥99.7th percentile BMI z-scores were classified as overweight, obese, and extremely obese. RESULTS The eligible sample included 656,038 children (48.8% girls). Overall, 210,492 (32.1%) children were overweight, 95,196 (14.5%) obese, and 19,926 (3.0%) extremely obese. While decreasing in the pre-COVID-19 period, annual prevalence estimates for overweight, obese, and extremely obese significantly (all p < 0.001) increased in the year after COVID-restrictions were implemented. However, after three years, overweight and obese prevalence estimates were no different to pre-COVID levels overall or stratified by sex for ethnicity and deprivation groups. Extreme obesity prevalence estimates also decreased but remained higher than pre-COVID levels. CONCLUSION The sharp and steep increases in prevalence estimates all dampened relatively quickly. The question remains whether these rates will continue to decrease in time. IMPACT Compared to pre-COVID-19 estimates, the prevalence of overweight, obesity and extreme obesity significantly and substantially increased for 4-year-old children in the immediate post-COVID-19 period. These post-COVID-19 prevalence estimates dampened relatively quickly, returning to pre-COVID-19 rates for overweight and obesity after 3 years. Inequities between ethnic and social deprivation groups in overweight and obesity prevalence estimates remained similar between pre- and post-COVID-19 periods.
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Affiliation(s)
- Philip J Schluter
- Te Kaupeka Oranga, Faculty of Health, Te Whare Wānanga o Waitaha, University of Canterbury, Christchurch, Aotearoa, New Zealand.
- School of Clinical Medicine, Primary Care Clinical Unit, The University of Queensland, Brisbane, QLD, Australia.
| | - Annabel Ahuriri-Driscoll
- Te Kaupeka Oranga, Faculty of Health, Te Whare Wānanga o Waitaha, University of Canterbury, Christchurch, Aotearoa, New Zealand
| | - Jalal Mohammed
- Te Kaupeka Oranga, Faculty of Health, Te Whare Wānanga o Waitaha, University of Canterbury, Christchurch, Aotearoa, New Zealand
| | - Sheetalpreet Singh
- Service Analysis and Modelling Evidence, Research and Analytics Evidence Research and Innovation, Ministry of Health, Wellington, Aotearoa, New Zealand
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