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World J Stomatol. Nov 20, 2013; 2(4): 67-70
Published online Nov 20, 2013. doi: 10.5321/wjs.v2.i4.67
Published online Nov 20, 2013. doi: 10.5321/wjs.v2.i4.67
Pharmacogenomics in oral diseases
Sridharan Gokul, Oral Pathology and Microbiology, YMT Dental College and Hospital, Kharghar, Navi Mumbai-410210, Maharashtra, India
Gokul Sapna, Department of Periodontics, Nair Hospital Dental College, Mumbai-400008, Maharashtra, India
Author contributions: Gokul S formulated the idea of writing the editorial; Gokul S and Sapna G together performed literature review and collected relevant data; Sapna G also contributed in proof reading the manuscript.
Correspondence to: Sridharan Gokul, MDS, Lecturer, Oral Pathology and Microbiology, YMT Dental College and Hospital, Kharghar, Institutional area, sector-4, Kharghar, Navi Mumbai-410210, Maharashtra, India. drgokuls@gmail.com
Telephone: +91-22-27744429 Fax: +91-22-27744427
Received: April 6, 2013
Revised: July 11, 2013
Accepted: July 17, 2013
Published online: November 20, 2013
Processing time: 227 Days and 15.2 Hours
Revised: July 11, 2013
Accepted: July 17, 2013
Published online: November 20, 2013
Processing time: 227 Days and 15.2 Hours
Core Tip
Core tip: Pharmacogenomics mainly focuses on the genetic determinants of drug response at the level of entire human genome. It primarily deals with tailoring of drug therapy among every individual based on their genetic make-up and identifying new targets in various diseases for drug therapy. Identification of gene polymorphisms in humans will aid in modulating drug therapy for individual needs as well as leading to discovery of target drugs. This editorial provides an overview of basic pharmacogenomics and its usefulness in oral diseases.