Rodella LF, Bonazza V. Platelet preparations in dentistry: How? Why? Where? When? World J Stomatol 2015; 4(2): 39-55 [DOI: 10.5321/wjs.v4.i2.39]
Corresponding Author of This Article
Luigi Fabrizio Rodella, MD, Department of Clinical and Experimental Sciences, Division of Anatomy and Physiopathology, University of Brescia, V.le Europa 11, 25123 Brescia, Italy. luigi.rodella@unibs.it
Research Domain of This Article
Dentistry, Oral Surgery & Medicine
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Stomatol. May 20, 2015; 4(2): 39-55 Published online May 20, 2015. doi: 10.5321/wjs.v4.i2.39
Platelet preparations in dentistry: How? Why? Where? When?
Luigi Fabrizio Rodella, Veronica Bonazza
Luigi Fabrizio Rodella, Veronica Bonazza, Department of Clinical and Experimental Sciences, Division of Anatomy and Physiopathology, University of Brescia, 25123 Brescia, Italy
Author contributions: Both authors contributed to this mansucript.
Conflict-of-interest: Dr. Rodella and Dr. Bonazza declare that there is no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Luigi Fabrizio Rodella, MD, Department of Clinical and Experimental Sciences, Division of Anatomy and Physiopathology, University of Brescia, V.le Europa 11, 25123 Brescia, Italy. luigi.rodella@unibs.it
Telephone: +39-030-3717485 Fax: +39-030-3717486
Received: February 13, 2015 Peer-review started: February 22, 2015 First decision: March 20, 2015 Revised: April 10, 2015 Accepted: April 28, 2015 Article in press: May 4, 2015 Published online: May 20, 2015 Processing time: 96 Days and 22.2 Hours
Abstract
The aim of this article is to review the outcomes of platelet preparations in dentistry. A structured electronic search discovered 348 articles, which described the use of autologous platelet concentrates with a relevance to clinical dentistry. Among these articles, 220 articles investigated platelet rich plasma, 99 investigated platelet rich fibrin, 22 investigated plasma rich in growth factors and 7 investigated the use of concentrated growth factors. Several studies reported beneficial treament outcomes in terms of enhanced bone and soft tissue regeneration.
Core tip: Autologous platelet concentrates (platelet-rich plasma, platelet rich fibrin, plasma rich in growth factors, concentrated growth factor), are blood derivatives, prepared from patient's own blood, reach in platelets, growth factors and cytokines, which can be used to promote guided tissue regeneration in dentistry and oral surgery.
