Published online May 20, 2015. doi: 10.5321/wjs.v4.i2.103
Peer-review started: December 4, 2014
First decision: January 20, 2015
Revised: January 26, 2015
Accepted: February 10, 2015
Article in press: February 12, 2015
Published online: May 20, 2015
Processing time: 168 Days and 18.2 Hours
The oral lichenoid lesion (OLL) is response that occurs on the oral mucosa. The OLL include allergic response to the dental materials, drugs, and on graft-vs-host disease (GVHD). OLL to dental material happen when restorative materials, most commonly amalgam, are in direct contact with the mucosa in sensitized individuals. Medications that produce OLL are oral hypoglycemic agents, angiotensin-converting enzyme inhibitors, and nonsteroidal anti-inflammatory agents. GVHD is a complication in bone marrow transplantation and OLL is a common lesion observed in this disease especially in chronic GVHD. The clinical and histological aspects of OLL are similar to oral lichen planus and turn it difficult to make a differential diagnosis. The purpose of this paper is review about OLL related to the dental materials, drug use and GVHD.
Core tip: There are various oral manifestations like oral lichen planus. These lesions are related to local or systemic factors and are important in oral diagnosis and patient’s management. Considering the increased of number of these lesion in current moment, we investigated previous publications and aim to present a literature review.