Case Report
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Stomatol. Feb 20, 2015; 4(1): 29-34
Published online Feb 20, 2015. doi: 10.5321/wjs.v4.i1.29
Unusual aggressive behavior of central giant cell granuloma following tooth extraction
Suwarna Dangore-Khasbage, Shirish S Degwekar, Rahul R Bhowate, Alka H Hande, Vidya K Lohe
Suwarna Dangore-Khasbage, Shirish S Degwekar, Rahul R Bhowate, Oral Medicine and Radiology, Sharad Pawar Dental College, Datta Meghe Institute of Medical Sciences, Maharashtra, Wardha 442001, India
Alka H Hande, Vidya K Lohe, Oral Pathology and Microbiology, SPDC, Datta Meghe Institute of Medical Sciences, Wardha 442001, India
Author contributions: All authors contributed to this work.
Ethics approval: Institutional Ethical Committee and Review Board of Datta Meghe Institute of Medical Sciences University, Wardha 442001.
Informed consent: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest: All my affiliations, corporate or institutional and all sources of financial support to this case study are properly acknowledged. I certify that do not have any commercial or associate interest that represents a conflict of interest in connection with the submitted manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Suwarna Dangore-Khasbage, Associate Professor, Oral Medicine and Radiology, Sharad Pawar Dental College, Datta Meghe Institute of Medical Sciences, Sawangi (M), Wardha, Wardha 442001, Maharashtra, India. dangore_suwarna@rediffmail.com
Telephone: +91-7152-231412 Fax: +91-7152-287731
Received: September 28, 2014
Peer-review started: September 30, 2014
First decision: October 21, 2014
Revised: November 14, 2014
Accepted: December 3, 2014
Article in press: January 12, 2015
Published online: February 20, 2015
Processing time: 138 Days and 16.3 Hours
Abstract

Central giant cell granuloma (CGCG) is found exclusively in jaws. Its etiopathogenesis is unclear; however it is suggested that it can arise as a reactive response to trauma. This report describes an aggressive variety of CGCG which raises a question; can extraction of tooth modify the behavior of CGCG? A 46 years old male had reported with a rapidly increasing intraoral and extraoral swelling of lower jaw following tooth extraction. Radiographic examination revealed a large multilocular lesion involving the body and ramus of mandible which had been proved to be aggressive CGCG on histopathological examination. The importance of radiographic examination prior to extraction of teeth and importance of inclusion of CGCG in jaw swellings associated with mobility of teeth or failure of healing sockets is emphasized.

Keywords: Aggressive; Central giant cell granuloma; Mandibular swelling; Extraction of teeth; Jaw

Core tip: This report describes an aggressive variety of central giant cell granuloma (CGCG) after extraction which raises a question; can extraction of tooth modify the behavior of CGCG? The importance of radiographic examination prior to extraction of teeth and importance of inclusion of CGCG in jaw swellings associated with mobility of teeth or failure of healing sockets is emphasized. Literature about clarity in clinical behavior, radiographic features and various treatment modalities of this one of the bony lesion of jaws are reviewed.