• diode laser
• low-level laser therapy
• peri-implant mucositis
• photodynamic therapy

• Humans
• Photochemotherapy/methods
• Lasers, Semiconductor/therapeutic use
• Tolonium Chloride/pharmacology
• Tolonium Chloride/therapeutic use
• Photosensitizing Agents/therapeutic use
• Photosensitizing Agents/pharmacology
• Peri-Implantitis/microbiology
• Peri-Implantitis/drug therapy
• Peri-Implantitis/therapy
• Female
• Male
• Middle Aged
• Stomatitis/microbiology
• Stomatitis/drug therapy
• Stomatitis/therapy
• Adult
• Bacterial Load/drug effects

• Diode laser
• laser assisted new attachment procedure
• new attachment
• periodontal pockets
• scaling and root planing

• Diode Laser
• Erythritol
• Periodontitis

• Adult
• Female
• Humans
• Male
• Middle Aged
• Aggregatibacter actinomycetemcomitans/isolation & purification
• Aggregatibacter actinomycetemcomitans/drug effects
• Air Abrasion, Dental/methods
• Bacterial Load/drug effects
• Dental Plaque Index
• Dental Scaling/methods
• Erythritol/therapeutic use
• Follow-Up Studies
• Lasers, Semiconductor/therapeutic use
• Periodontal Attachment Loss/therapy
• Periodontal Attachment Loss/microbiology
• Periodontal Index
• Periodontal Pocket/therapy
• Periodontal Pocket/microbiology
• Periodontitis/microbiology
• Periodontitis/therapy
• Periodontitis/drug therapy
• Porphyromonas gingivalis/isolation & purification
• Porphyromonas gingivalis/drug effects
• Root Planing/methods
• Treatment Outcome

• Mansoura University

• Clinical parameters
• laser surgery
• non-laser surgery
• periodontitis
• treatment efficacy

• electrocautery
• laser
• lower lip
• mucocele
• scalpel

• Dental calculus
• Laser therapy
• Root planing
• Ultrasonics

• diode laser
• doxycycline
• periodontitis
• root planing
• scaling

• Aggregatibacter actinomycetemcomitans
• Antibiotic
• Diode laser
• Gingival crevicular fluid
• Periodontitis
• Porhyromonas Gingivalis
• Real-time polymerase chain reaction

• Humans
• Metronidazole/therapeutic use
• Spiramycin/therapeutic use
• Lasers, Semiconductor/therapeutic use
• Retrospective Studies
• Follow-Up Studies
• Periodontitis/drug therapy
• Periodontitis/microbiology
• Anti-Bacterial Agents/therapeutic use
• Dental Scaling/methods
• Root Planing/methods
• Chronic Periodontitis/therapy

• Alexandria University

• Diode laser
• Low-level laser therapy
• Vestibuloplasty
• Wound healing

• Humans
• Low-Level Light Therapy/methods
• Lasers, Semiconductor/therapeutic use
• Vestibuloplasty
• Wound Healing
• Laser Therapy

• Biostimulatory
• Dentistry
• Near infrared
• Osteogenesis
• Photobiomodulation

• Low-Level Light Therapy/methods
• Osteogenesis
• Light
• Bone Remodeling
• Dentistry

• Enamel matrix derivative
• Gingival crevicular fluid
• Inflammation
• Nonsurgical therapy
• Periodontitis

• Humans
• Periodontitis/therapy
• Dental Enamel Proteins/therapeutic use
• Treatment Outcome
• Cytokines
• Periodontal Attachment Loss/drug therapy
• Follow-Up Studies
• Alveolar Bone Loss/surgery

• Medical University of Vienna

• debridement
• dental calculus
• diode laser
• root planing
• scaling

• Humans
• Lasers, Semiconductor/therapeutic use
• Dental Calculus/therapy
• Dental Scaling
• Research Design
• Sweden

• adjunctive laser therapy
• evidence-based study
• non-surgical periodontal treatment
• systematic reviews
• treatment outcomes

• effective hemostasis
• hemostasis strategies
• nanomaterials
• nanotechnology
• wound healing

• 2019J05031 Natural Science Foundation of Fujian Province

• Nd:YAG laser
• aesthetic
• ceramic bur
• gingival melanin pigmentation
• non-smokers
• smokers

• Nd:YAG lasers
• Non-surgical periodontal debridement
• Periodontitis
• Smoking

• Humans
• Smokers
• Lasers, Solid-State/therapeutic use
• Single-Blind Method
• Matrix Metalloproteinase 8
• Periodontal Pocket/therapy
• Root Planing/methods
• Periodontitis/surgery
• Follow-Up Studies

• PCR
• non-surgical periodontal therapy
• photodynamic therapy
• randomized controlled clinical study

• Diode laser
• Erbium laser
• IL-10
• Laser therapy
• MMP-13
• Periodontitis
• SRP

• laser therapy
• lasers
• periodontics
• periodontitis
• root planing

• CO2
• Diode
• Gingiva
• Laser
• Melanin
• Pigmentation

The goals of periodontal therapy are to prevent the disease, arrest the disease progression, and regeneration of lost periodontium. Diode laser gained popularity in periodontal practice with a wide range of potential benefits.

This study aims to evaluate and compare the clinical effects of laser-assisted open flap debridement (OFD) versus conventional OFD for the periodontitis treatment.

A split-mouth, randomized clinical trial was conducted on fifteen participants with periodontitis having probing pocket depths (PPD) ≥5 mm. A total of 30 sites, two sites in each patient, were randomly divided into two groups. Group A received conventional OFD, and Group B received laser-assisted OFD. The assessment of PPD, relative attachment level (RAL), modified sulcular bleeding index (mSBI) was done at baseline, 3 months, and 6 months. Wound healing index (WHI) was assessed at 3^rd and 7^th day postsurgery, patient response to pain using visual analog scale (VAS) was assessed immediately, 1 day, and 1 week after surgery.

The results revealed a significant reduction in PPD, mSBI, and gain in RAL within the groups from baseline to 3 months and 6 months. Intergroup comparison showed a significant difference in PPD, RAL, mSBI, WHI and VAS scores.

The use of 980 nm diode laser provided additional benefits over conventional flap therapy.

As dental lasers are becoming more popular in the branch of oral medicine for its various advantages and applications, this study was carried out to evaluate better mode of obtaining oral biopsies which is a common and inevitable procedure for providing final diagnosis in majority of conditions.

In this study, a total of 60 patients who required biopsy for final diagnosis of oral mucosal lesions as part of diagnosis in department of Oral Medicine were selected, out of which 30 were subjected to scalpel biopsies and 30 patients were subjected to diode laser biopsies. A 980 nm Zolar plus diode laser was used for the study. Out of 30 patients who were subjected to laser biopsies, 3W continuous mode settings were used for 15 patients and 3W pulsed mode was used for 15 patients. The specimens were sent to Department of Oral Pathology for histopathological evaluation to provide the final diagnosis. The time taken for each patient, volume of local anesthesia, during operative, postoperative pain scale, and co-relation of provisional and final diagnosis was noted for comparison purpose and the pathologist comments, peripheral tissue damage and artifact's for each slide were noted.

The study results showed the postoperative pain was comparatively less in diodlaser than scalpel, the lasers were patient friendly as the heammorage was negligible when compared to scalpel and suturing was not required. The pulsed mode in diode laser was advantageous over continuous mode when amount of thermal damage and postoperative pain score was compared.

The results showed that oral biopsies can be made better using diode lasers, by having thorough knowledge on the device.

• Diode laser
• Meta-analysis
• Periodontal debridement
• Periodontitis
• Scaling and root planing

• case report
• case study
• diode laser
• mucocele

• Laser(s)
• Non-surgical periodontal therapy
• Periodontal surgery
• Periodontitis
• Scaling and root planing

• implant
• laser treatment
• pontic site preservation

Lasers have been well integrated in clinical dentistry for the last two decades, providing clinical alternatives in the management of both soft and hard tissues with an expanding use in the field of dental materials. One of their main advantages is that they can deliver very low to very high concentrated power at an exact point on any substrate by all possible means. The aim of this review is to thoroughly analyze the use of lasers in the processing of dental materials and to enlighten the new trends in laser technology focused on dental material management. New approaches for the elaboration of dental materials that require high energy levels and delicate processing, such as metals, ceramics, and resins are provided, while time consuming laboratory procedures, such as cutting restorative materials, welding, and sintering are facilitated. In addition, surface characteristics of titanium alloys and high strength ceramics can be altered. Finally, the potential of lasers to increase the adhesion of zirconia ceramics to different substrates has been tested for all laser devices, including a new ultrafast generation of lasers.

• laser
• sintering
• surface micro-topography
• surface texturing
• titanium
• zirconia

Due to the limitations of scaling and root planing (SRP) in chronic periodontitis (CP) management, research has been focused on utilising additional therapies to enhance conventional treatment methods. The present systematic review is aimed to appraise the accessible scientific evidence of in vivo human studies to establish the effectiveness of adjunctive diode (λ 808- λ 980nm) laser treatment to SRP in CP.

This systematic review was conducted following the PRISMA statement guidelines. The review protocol is registered in PROSPERO (CRD 42021227695). The search strategies were based on structured electronic and manual (with appropriate keywords) and were conducted to collect the applicable published data on RCTs studies (in vivo human), spanning over ten years between August 2010 and August 2020. The articles were selected to address the following research focus question: “Does diode laser (λ 808- λ 980nm) therapy have superior effects as an adjunct to SPR, compared to SRP alone, in terms of clinical or microbiological or immunological profiles in the management of CP?”

Fifteen articles met the eligibility criteria and are included in this review. A wide range of discrepancies and inconsistencies were shown in the outcomes of the laser and SPR treatment modality, compared to SRP alone. The data on standardised study protocol, optimal laser parameters and outcome measurements were inconclusive, and a high risk of bias in the majority of the studies observed, which are crucial in establishing a homogenous and reproducible protocol.

In light of the confined evidence-based data and critical evaluation of this systematic review, the efficacy of adjunctive diode laser treatment ranging between 808 and 980nm to SRP remains debatable. The observational quality of the present systematic review was emphasised after scrutinising the available data, and an attempt to propose a laser protocol for future RCTs consideration was a great challenge due to an absence of clear and standardised recommendations in delivering a reliable laser protocol which can be replicable by future investigators. RCTs with robust methodology are warranted.

• RCTs
• chronic periodontitis
• diodes laser treatment
• high intensity laser
• non-surgical periodontal therapy
• randomised controlled trials studies
• scaling and root planing
• systematic diseases

• Chronic periodontitis
• diode laser
• microbiological analysis
• modified Widman flap

To evaluate the clinical and biochemical efficacy of laser therapy as an adjunct to non‐surgical treatment in chronic periodontitis.

A systematic search was performed through the PubMed, EMBASE, and Cochrane Library for eligible articles published as of May 2, 2020, supplemented by information search in the System for Information on Programme Literature in Europe and a manual literature search. Only randomized controlled trials (RCTs) used to compare the adjunctive use of laser and non‐surgical treatment alone with an observation period of at least 6 months were included.

Sixteen RCTs with a total of 525 subjects were included. Meta‐analysis suggested that the additional use of laser to scaling and root planing (SRP) showed significant superiority over SRP alone among most of clinical parameters involved. Regarding the GCF, although volume in the laser group was lower at week 4 and 12, no significant difference was found regarding the cytokines level. Subgroup analysis revealed that the combined therapy produced no significant difference in PD, CAL and PI at most time points for studies in respect to smokers. No treatment‐related adverse events had been reported in the included studies.

Pooled analysis suggested that laser‐assisted non‐surgical treatment improved clinical outcome to SRP alone in the management of non‐smoking chronic periodontitis patients.

• chronic periodontitis
• laser
• meta-analysis
• non-surgical periodontal treatment
• systematic review

• Inflamation
• PGE2
• SP
• miniscrew
• pain

• PBM
• cell proliferation
• human gingival fibroblasts
• photobiomodulation
• soft tissue regeneration

• PBS3/A7/18/2015 "LASDER"National Center for Research and Development in Poland

Background. Conventional mechanical debridement alone cannot eliminate bacteria and their products from periodontal pockets. Adjunctive therapies improve tissue healing through detoxification and bactericidal effects. Photodynamic therapy (PDT) is a non-invasive treatment procedure that involves the use of a dye as a photosensitizer to attach to the target cell and be activated by a photon of an appropriate wavelength. This study aimed to assess the effectiveness of PDT in treating periodontitis as an adjunct to scaling and root planing.

Methods. Fifteen subjects with chronic periodontitis were treated randomly with scaling and root planing (SRP), followed by a single PDT (test) or SRP (control) episode alone. Full-mouth plaque index (PI), sulcus bleeding index (SBI), probing depth (PD), and clinical attachment level (CAL) were assessed at baseline and 1-month and 3-month intervals. Microbiological evaluation of Porphyromonas gingivalis (Pg) in subgingival plaque samples was performed using a commercially available real-time polymerase chain reaction.

Results. The results revealed a significant difference in PI, SBI, PD, CAL, and microbiological parameters between the groups one and three months after treatment.

Conclusion. A combination of PDT and SRP gave rise to a significant improvement in clinical and microbiological parameters in patients with chronic periodontitis.

• Chronic periodontitis
• Hotosensitizing agents
• Photodynamic therapy
• Polymerase chain reaction
• Porphyromonas gingivalis

Perforations in the furcation area are common procedural accidents that can impact the outcome of treatment. There are many bioactive materials available to repair these defects.

The purpose of this study was to determine and compare the effect of 25% aluminum chloride solution, 20% ferric sulfate solution, and a 980-nm diode laser, when used for hemostasis, on the dislocation resistance of Biodentine placed to repair furcation perforation.

This in vitro study was conducted on fifty extracted human permanent mandibular molars, with ten teeth in each group. The stimulated perforations were contaminated with blood, except for one group. The contaminated groups were either treated with aluminum chloride, ferric sulfate, diode laser, or none at all. All the perforations were restored with Biodentine and tested for push-out bond strength.

One-way analysis of variance and Tukey's HSD post hoc test were applied with a level of significance set at 0.05.

The dislocation resistance of Biodentine was found to be highest when aluminum chloride or diode laser was used for arresting bleeding. In contrast, the ferric sulfate group gave the lowest value for push-out bond strength (P < 0.05).

According to the present study, the use of ferric sulfate as a hemostatic agent showed a negative effect on the bond strength of the calcium silicate cement to dentin. Furthermore, Biodentine performed better when diode laser and aluminum chloride were used for hemostasis.

Assessment of the efficacy of a single 810 nm diode laser application as an adjunctive treatment modality during the first intervention of non-surgical periodontal therapy (NPT). 25 patients diagnosed with chronic periodontitis underwent a split-mouth randomised control trial. The periodontal pockets of the test quadrants were treated with an 810 nm diode laser as an adjunct to NPT (Picasso GaAlAs; AMD Lasers). The laser was set at 1.0 W continuous wave, 400 µm tip, 796 W/cm² peak power density and a 32 J/cm² energy density. Therapeutic outcomes were evaluated based on the clinical parameters, which included probing pocket depth, recession, clinical attachment level, full mouth plaque score, full mouth bleeding on probing and tooth mobility. The baseline bacterial collection was completed from the periodontal pockets and then re-evaluated at 6 weeks. Clinical parameters demonstrated no statistical difference, with the exception of a statistically significant (P < 0.05) reduction in bleeding on probing for the test side. The test side resulted in a statistical increase of Capnocytophagaspecies and Treponemadenticola. The single application of the diode laser did not significantly improve the bacterial nor the clinical parameters in patients with chronic periodontitis.

Trial registration number: PACTR201909915338276.

Background: Lasers are widely used in medicine in soft and hard tissue surgeries and biostimulation. Studies found in literature typically compare the effects of single-wavelength lasers on tissues or cell cultures. In our study, we used a diode laser capable of emitting three components of visible light (640 nm, red; 520 nm, green; 450 nm, blue) and combining them in a single beam. The aim of the study was to assess the effects of laser radiation in the visible spectrum on tissue in vitro, depending on the wavelength and pulse width. Methods: All irradiations were performed using the same output power (1.5 W). We used various duty cycles: 10, 50, 80 and 100% with 100 Hz frequency. Maximum superficial temperature, rate of temperature increase and lesion depth were investigated. Results: Maximum superficial temperature was observed for 450 + 520 nm irradiation (100% duty cycle). The highest rate of increase of temperature was noted for 450 + 520 nm (100% duty cycle). Maximum lesion depth was observed in case of three-wavelength irradiation (450 + 520 + 640 nm) for 100, 80 and 50% duty cycles. Conclusions: The synergistic effect of two-wavelength (450 + 520 nm) irradiation was observed in case of maximum temperature measurement. The deepest depth of lesion was noted after three-wavelength irradiation (450 + 520 + 640 nm).

• diode laser
• diode laser surgery
• interaction light-tissue
• multi-wavelength laser

• cancer
• carbon nanotubes
• graphene
• photodynamic therapy
• photosensitizers
• phototherapy

• 98337 South African Research Chairs Initiative of the Department of Science and Technology and National Research Foundation of South Africa, University of Johannesburg (URC) and National Laser Centre (NLC)-Rental Pool Program

• depigmentation
• gingival hyperpigmentation
• lasers
• melanin

• Bone regeneration
• LED
• Osteoblasts
• Photobiomodulation therapy

• chronic periodontitis
• enamel matrix proteins
• interleukin-1beta

Nonsurgical and surgical therapies along with local and systemic antibiotic regimens have been advocated in the treatment of periodontitis. Due to increasing risk of developing antibiotic resistance and inability of nonsurgical periodontal therapy to completely eradicate the pathogenic microorganisms, lasers have been used as an adjunct to conventional therapy.

The aim of the present study is to evaluate the effectiveness of the use of diode lasers as adjunct to scaling and root planing (SRP) compared to SRP alone on various clinical and microbiologic parameters in chronic periodontitis patients.

Patients were taken from the department of periodontology and implantology, who were having chronic periodontitis.

A total of forty patients participated in the study and they were divided into Group I – the test group (SRP + diode laser) and Group II – the control group (SRP alone). The following clinical parameters were assessed: oral hygiene index simplified; clinical attachment level (CAL); probing pocket depth (PPD); bleeding on probing (BOP) at baseline, 4 weeks, and 12 weeks after the treatment; and colony-forming units (CFUs) 1 week postoperatively.

The statistical analysis was performed using paired t-test, unpaired t-test, Wilcoxon signed-rank test, and Mann–Whitney test.

There was reduction in BOP, PPD, and gain in CAL from baseline to 3 months and also a reduction in CFU 1 week postoperatively.

There was a significant improvement in clinical parameters in test group (SRP + laser) as compared to the control group (SRP alone).

• Chronic periodontitis
• diode laser
• laser therapy
• nonsurgical periodontal therapy

• LANAP
• Laser
• Oral surgery
• Piezo

• crown lengthening
• laser
• minimally invasive therapy

In our article, we described a clinical case of a patient with an acute periostitis of the maxilla with a comorbidity (primary immune thrombocytopenia, resistant form) who was treated using laser technology allowing us to provide good results: an intensive regeneration process and a decreased risk of developing infection complications and unpleasant signs for the patient, such as postoperative edema and intraoperative and postoperative pain syndrome.

• Antimicrobial photodynamic therapy
• Diode laser
• Low-level laser therapy
• Periodontitis
• Transgingival irradiation

The objective of the current study is to analyze the correlation between cytokine levels and periodontal parameters in aggressive periodontitis patients before and after periodontal treatment that was performed by using two different laser therapies.

Twenty-six generalized aggressive periodontitis patients were treated with three different methods (SRP, SRP+diode laser, and SRP+Er,Cr:YSGG laser) applied to three different half-jaws in the same patients. Pre- and posttreatment clinical periodontal parameters and GCF IL-1β and IL-37 levels were measured.

There was a statistically significant decrease (p < 0.05) between pretreatment and posttreatment clinical periodontal parameters and IL-1β and IL-37 levels. When the reduction rates of IL-37 and IL-1β levels after treatment were evaluated, the decrease in IL-37 and IL-1β levels after treatment was lowest in the SRP group and highest in the SRP+Er,Cr:YSGG group. In addition, the amount of decrease in IL-1β in SRP+diode and SRP+Er,Cr:YSGG groups was found to be higher than that in IL-37. Furthermore, there was a positive correlation between IL-37 and IL-1β in all groups (p < 0.01).

Er,Cr:YSGG laser is more effective than diode laser for the treatment of aggressive periodontitis. IL-37 and IL-1β are cytokines that function together and thus must be evaluated together.

• laser
• nonsurgical periodontal therapy
• periodontal disease
• wound healing

• Adult
• Aged
• Dental Scaling/methods
• Female
• Humans
• Lasers, Solid-State/therapeutic use
• Male
• Middle Aged
• Periodontal Debridement/methods
• Periodontitis/metabolism
• Periodontitis/pathology
• Periodontitis/therapy
• Periodontium/metabolism
• Periodontium/pathology
• Proliferating Cell Nuclear Antigen/metabolism
• Root Planing/methods
• Treatment Outcome
• Ultrasonic Therapy/methods
• Wound Healing