Minireviews
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Otorhinolaryngol. May 28, 2016; 6(2): 23-32
Published online May 28, 2016. doi: 10.5319/wjo.v6.i2.23
Positron-emission tomography/computed tomography imaging in head and neck oncology: An update
Viet D Nguyen, Bundhit Tantiwongkosi, Wyatt J Weinheimer, Frank R Miller
Viet D Nguyen, Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, United States
Bundhit Tantiwongkosi, Division of Neuroradiology, Department of Radiology and Otolaryngology Head Neck Surgery, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, United States
Wyatt J Weinheimer, Frank R Miller, Department of Otolaryngology Head Neck Surgery, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, United States
Author contributions: All four authors actively and equally contributed to the writing and editing of the article as well as gathering the necessary illustrations.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Viet D Nguyen, MD, Department of Radiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mail Code 7800, San Antonio, TX 78229, United States. nguyenvd@uthscsa.edu
Telephone: +1-210-5675535
Received: August 25, 2015
Peer-review started: August 27, 2015
First decision: September 28, 2015
Revised: November 9, 2015
Accepted: March 17, 2016
Article in press: March 18, 2016
Published online: May 28, 2016
Processing time: 259 Days and 0.9 Hours
Core Tip

Core tip: In the pre-treatment phase, positron-emission tomography/computed tomography (PET/CT) is valuable in the evaluation of patients with carcinoma of unknown primary origin, detection of synchronous second primary tumor, staging of cervical lymph node metastasis and assessment for distant metastases. In the post-treatment phase, PET/CT is helpful in evaluating treatment response, detecting residual or recurrent tumor and excluding distant metastases. Prognostic factors derived from PET/CT metabolic and functional data are useful in predicting tumor aggressiveness with implication on patient’s survivability, and facilitate selection of treatment modality and personalized treatment options.