Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Obstet Gynecol. Dec 6, 2020; 9(1): 1-10
Published online Dec 6, 2020. doi: 10.5317/wjog.v9.i1.1
Published online Dec 6, 2020. doi: 10.5317/wjog.v9.i1.1
Myasthenia gravis and pregnancy
Goun Je, Mehdi Ghasemi, Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, United States
Author contributions: Je G and Ghasemi M made contribution to the conception and design of the review paper’s content and literature review; Je G wrote the initial draft of the paper; Ghasemi M and Je G critically reviewed, edited and finalized the paper for submission.
Conflict-of-interest statement: The authors declare no conflict of interest related to this work.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mehdi Ghasemi, MD, Assistant Professor, Department of Neurology, University of Massachusetts Medical School, 55 Lake Avenue North, Room S5-770, Worcester, MA 01665, United States. m82.ghasemi@gmail.com
Received: May 22, 2020
Peer-review started: May 22, 2020
First decision: October 6, 2020
Revised: November 9, 2020
Accepted: November 17, 2020
Article in press: November 17, 2020
Published online: December 6, 2020
Processing time: 198 Days and 19.9 Hours
Peer-review started: May 22, 2020
First decision: October 6, 2020
Revised: November 9, 2020
Accepted: November 17, 2020
Article in press: November 17, 2020
Published online: December 6, 2020
Processing time: 198 Days and 19.9 Hours
Core Tip
Core Tip: Myasthenia gravis (MG) is an autoimmune disorder of the neuromuscular junction that overall has higher incidence in women than men. This disease can variably affect pregnancy; and specific considerations need to be taken by a multidisciplinary team (including obstetricians/gynecologists, neurologists, and anesthesiologists) in pregnant women during their pregnancy, delivery, and post-partum period. We herein discuss about our understanding about MG presentation and its effect on pregnancy and vice versa, safe therapeutic approaches for MG as well as pregnancy/Labor complications, and finally specific fetal and neonatal considerations in MG pregnant women.