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World J Obstet Gynecol. May 10, 2014; 3(2): 28-34
Published online May 10, 2014. doi: 10.5317/wjog.v3.i2.28
Published online May 10, 2014. doi: 10.5317/wjog.v3.i2.28
Pathological conditions predisposing to infertility and gynaecological neoplasia
Bassma Mohamed El Sabaa, Department of Pathology, Alexandria Faculty of Medicine, Alexandria University, Alexandria 21111, Egypt
Author contributions: El Sabaa BM solely wrote the paper.
Correspondence to: Bassma Mohamed El Sabaa, MD, PhD, Associate Professor, Department of Pathology, Alexandria Faculty of Medicine, Alexandria University, El Shatby, Alexandria 21111, Egypt. bassma_el_sabaa@yahoo.com
Telephone: +20-12-27574826 Fax: +20-3-4294963
Received: January 6, 2013
Revised: March 4, 2013
Accepted: April 10, 2013
Published online: May 10, 2014
Processing time: 148 Days and 7 Hours
Revised: March 4, 2013
Accepted: April 10, 2013
Published online: May 10, 2014
Processing time: 148 Days and 7 Hours
Core Tip
Core tip: Female infertility is now acknowledged as a risk factor of gynecological neoplasia. In this mini-review we conduct a comprehensive literature review to verify this prospect. The principal pathogenetic mechanisms linking infertility to gynecological neoplasia are pointed out. The relationship between each of endometriosis and polycystic ovary syndrome and gynecological neoplasia is explored in depth. We discuss the relation of Turner’s syndrome (the prototype of ovarian dysgenesis) to gynecological cancer. Is there a relation between increased risk of ovarian cancer and ovulation-stimulation drugs? We will attempt to answer this question.