Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Obstet Gynecol. Nov 29, 2022; 11(4): 40-46
Published online Nov 29, 2022. doi: 10.5317/wjog.v11.i4.40
Primary peritoneal hemangioendothelioma simulating an ovarian cyst: A case report and review of literature
Claudio Spinelli, Marco Ghionzoli, Silvia Strambi
Claudio Spinelli, Marco Ghionzoli, Silvia Strambi, Pediatric and Adolescent Surgery Division, Department of Surgical, Medical, Molecular Pathology and of the Critic Area, University of Pisa, Pisa 56126, Italy
Author contributions: Spinelli C conceived and designed the analysis; Strambi S collected the data and performed the analysis; Spinelli C, Ghionzoli M, Strambi S, contributed data or analysis tools and wrote the paper.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors report no relevant conflict of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Claudio Spinelli, MD, Full Professor, Professor, Surgeon, Pediatric and Adolescent Surgery Division, Department of Surgical, Medical, Molecular Pathology and of the Critic Area, University of Pisa, Via Paradisa 2, Pisa 56126, Italy. claudio.spinelli@unipi.it
Received: July 18, 2022
Peer-review started: July 18, 2022
First decision: August 1, 2022
Revised: August 5, 2022
Accepted: November 23, 2022
Article in press: November 23, 2022
Published online: November 29, 2022
Core Tip

Core Tip: In this article we describe the case of a woman of middle age who came to our observation for chronic abdominal pain. Diagnostic examinations showed a mass of undefined nature which simulated an ovarian cyst due to its pelvic position and its morphological features. Histological examination revealed a primary peritoneal hemangioendothelioma, which is an extremely rare form of epithelioid hemangioendothelioma, with only 12 cases reported in the literature to date. Epithelioid hemangioendothelioma has a very heterogenous spectrum of disease that varies from an indolent to a metastasizing aggressive disease, with the liver, lung and bone being the primarily involved organs.