Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Obstet Gynecol. May 20, 2022; 11(2): 8-16
Published online May 20, 2022. doi: 10.5317/wjog.v11.i2.8
Microglandular hyperplasia-like mucinous adenocarcinoma of the endometrium: A rare case report
Helen J Trihia, Efthymia Souka, George Galanopoulos, Kitty Pavlakis, Loukas Karelis, Alexandros Fotiou, Ioannis Provatas
Helen J Trihia, Efthymia Souka, George Galanopoulos, Loukas Karelis, Department of Pathology, ‘Metaxas’ Memorial Cancer Hospital, Piraeus 18537, Greece
Kitty Pavlakis, Department of Pathology, National & Kapodistrian University of Athens, Athens 11527, Greece
Kitty Pavlakis, Department of Pathology, ‘IASO’ General Maternity & Gynecological Clinic, Maroussi, Athens 15123, Greece
Alexandros Fotiou, Department of Gynaecologic Oncology, ‘Metaxas’ Memorial Cancer Hospital, Piraeus 18537, Greece
Ioannis Provatas, Department of Pathology, Evangelismos District General Hospital, Athens 10676, Greece
Author contributions: Trihia HJ diagnosed the case and authored the paper; Pavlakis K confirmed diagnosis (second opinion); Fotiou A supported surgical management; Galanopoulos G took macroscopic photos; Rest co-authors helped in the review of the manuscript.
Informed consent statement: There is oral and written informed consent from the patient, if requested.
Conflict-of-interest statement: There is no conflict of interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Helen J Trihia, MD, MSc, PhD, Chief Doctor, Department of Pathology, ‘Metaxas’ Memorial Cancer Hospital, 51, Mpotassi str, Piraeus 18537, Greece. eltrix@otenet.gr
Received: February 13, 2021
Peer-review started: February 13, 2021
First decision: March 31, 2021
Revised: May 12, 2021
Accepted: March 27, 2022
Article in press: March 27, 2022
Published online: May 20, 2022
Processing time: 458 Days and 17.4 Hours
Core Tip

Core Tip: When microglandular hyperplasia (MGH)-like proliferation is detected in the endometrial curettage of a postmenopausal woman, the pathologists must be vigilant for endometrial MGH-like endometrial adenocarcinoma type of carcinoma, as it may be misdiagnosed. The examination of scant biopsy specimens remains a challenge. Its recognition can avoid underdiagnosis and mistreatment of the patient.