Moore LE. Thyroid disease in pregnancy: A review of diagnosis, complications and management. World J Obstet Gynecol 2016; 5(1): 66-72 [DOI: 10.5317/wjog.v5.i1.66]
Corresponding Author of This Article
Lisa E Moore, MD, MS, FACOG, ARDMS, Department of Obstetrics and Gynecology, Texas Tech Health Sciences Center, 4801 Alberta Ave., El Paso, TX 79905, United States. lisa.e.moore@ttuhsc.edu
Research Domain of This Article
Obstetrics & Gynecology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Obstet Gynecol. Feb 10, 2016; 5(1): 66-72 Published online Feb 10, 2016. doi: 10.5317/wjog.v5.i1.66
Thyroid disease in pregnancy: A review of diagnosis, complications and management
Lisa E Moore
Lisa E Moore, Department of Obstetrics and Gynecology, Texas Tech Health Sciences Center, El Paso, TX 79905, United States
Author contributions: Moore LE solely contributed to this paper.
Conflict-of-interest statement: No potential conflicts of interest to report.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Lisa E Moore, MD, MS, FACOG, ARDMS, Department of Obstetrics and Gynecology, Texas Tech Health Sciences Center, 4801 Alberta Ave., El Paso, TX 79905, United States. lisa.e.moore@ttuhsc.edu
Telephone: +1-915-2155127 Fax: +1-915-5456946
Received: July 9, 2015 Peer-review started: July 14, 2015 First decision: September 22, 2015 Revised: December 1, 2015 Accepted: December 18, 2015 Article in press: December 21, 2015 Published online: February 10, 2016 Processing time: 206 Days and 15.2 Hours
Abstract
Malfunction of the thyroid gland is the second most common endocrine disorder encountered during pregnancy. It is well known that overt disease of the thyroid gland, either hyper or hypo can adversely affect pregnancy outcome. There is also an ongoing debate surrounding the issue of subclinical hypothyroidism and its effect on the cognitive development of the unborn child. The goal of this paper is to present a systematic review of the literature and the current recommendations for diagnosis and treatment of thyroid disease in pregnancy and postpartum.
Core tip: Uncontrolled thyroid disease in pregnancy is associated with significant morbidity and mortality for both mother and fetus. Timely diagnosis and adequate treatment ameliorates the risk of complications. Treatment of subclinical hypothyroidism in pregnancy with the goal of improving the cognitive outcome for the fetus has not been shown to be useful and is not currently recommended.
