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Figure 1 Pre-operative magnetic resonance imaging of the cervical spine.
On coronal (A) and sagittal (B) view showed an extradural soft tissue mass at C2-C4 levels. After debulking of the mass (C) and at 10 mo post-operative follow up (D) showed markedly decreased mass effect on the cervical cord.
Figure 2 Histopathology of the tumor.
A: High-power micrographs show a spindle cell lesion with focally increased cellularity and nuclear atypia; B: Scattered clusters of mature-appearing, small round cells with moderately abundant eosinophilic cytoplasm (arrow head) resembling a skeletal muscle differentiation.
Figure 3 Immunohistochemistry.
The spindle cells are diffusely and strongly positive staining for vimentin (A) and focally positive for S-100 protein (B); The small round cells with skeletal muscle morphology showed positivity of muscle specific actin (C); The Ki-67 immunostaining shows low labeling index (D).
- Citation: Zhang M, Weaver M, Khurana JS, Mukherjee AL. Low grade spinal malignant triton tumor with mature skeletal muscle differentiation. World J Neurol 2013; 3(3): 75-78
- URL: https://www.wjgnet.com/2218-6212/full/v3/i3/75.htm
- DOI: https://dx.doi.org/10.5316/wjn.v3.i3.75