Basic Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Neurol. May 31, 2023; 9(3): 17-27
Published online May 31, 2023. doi: 10.5316/wjn.v9.i3.17
Alcohol intolerance and myalgic encephalomyelitis/chronic fatigue syndrome
Jessica Maciuch, Leonard A Jason
Jessica Maciuch, Leonard A Jason, Center for Community Research, DePaul University, Chicago, IL 60614, United States
Author contributions: Maciuch J and Jason LA contributed equally to this work, designed the research, performed the research, analyzed data, and wrote the paper.
Institutional review board statement: Approval obtained from the DePaul Institutional Review Board.
Institutional animal care and use committee statement: Animals were not used in this study.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: Data will be shared when investigators contact the corresponding author.
ARRIVE guidelines statement: The authors have read the ARRIVE guidelines, and the manuscript was prepared and revised according to the ARRIVE guidelines.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Leonard A Jason, PhD, Professor, Center for Community Research, DePaul University, 990 W Fullerton Ave, Chicago, IL 60614, United States. ljason@depaul.edu
Received: December 27, 2022
Peer-review started: December 27, 2022
First decision: April 13, 2023
Revised: April 13, 2023
Accepted: May 6, 2023
Article in press: May 6, 2023
Published online: May 31, 2023
Processing time: 154 Days and 9.8 Hours
ARTICLE HIGHLIGHTS
Research background

There is a need to objectively measure alcohol intolerance among those with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

Research motivation

There is a need to determine if those with ME/CFS with alcohol intolerance are more symptomatic than those without alcohol intolerance.

Research objectives

We aimed to carefully measure alcohol intolerance and determine its effects on those with ME/CFS.

Research methods

We collected data from patients with ME/CFS using a validated symptom questionnaire.

Research results

We were able to determine that those with alcohol intolerance were more symptomatic than those without it among a sample of patients with ME/CFS.

Research conclusions

It is important to measure alcohol intolerance carefully among patients who are not going to report using alcohol over the preceding months.

Research perspectives

It is possible to reliably and validly measure alcohol intolerance among those with ME/CFS, and this should guide future research in this area.