Kilby KJ, Anderson-Quiñones C, Pierce KR, Gabrah K, Seth A, Brunson A. Late ischemic stroke and brachiocephalic thrombus in a 65-year-old patient six months after COVID-19 infection: A case report. World J Hematol 2022; 9(2): 13-19 [DOI: 10.5315/wjh.v9.i2.13]
Corresponding Author of This Article
Kristen Jane Kilby, PharmD, Pharmacist, Pharmacy, Baptist Memorial Hospital-Memphis, 6019 Walnut Grove Road, Memphis, TN 38120, United States. kristen.kilby@bmhcc.org
Research Domain of This Article
Medicine, General & Internal
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Hematol. Apr 25, 2022; 9(2): 13-19 Published online Apr 25, 2022. doi: 10.5315/wjh.v9.i2.13
Late ischemic stroke and brachiocephalic thrombus in a 65-year-old patient six months after COVID-19 infection: A case report
Kristen Jane Kilby, Catherine Anderson-Quiñones, Keith Richard Pierce, Kirollos Gabrah, Ankur Seth, Allison Brunson
Kristen Jane Kilby, Allison Brunson, Department of Pharmacy, Baptist Memorial Hospital-Memphis, Memphis, TN 38120, United States
Catherine Anderson-Quiñones, Keith Richard Pierce, Ankur Seth, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, United States
Kirollos Gabrah, College of Osteopathic Medicine, New York Institute of Technology, Jonesboro, AR 72401, United States
Author contributions: Anderson-Quiñones C and Seth A were the patient’s hospitalists, reviewed the literature and contributed to manuscript drafting; Kilby KJ, Gabrah K, and Pierce KR contributed to manuscript drafting; Brunson A was responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kristen Jane Kilby, PharmD, Pharmacist, Pharmacy, Baptist Memorial Hospital-Memphis, 6019 Walnut Grove Road, Memphis, TN 38120, United States. kristen.kilby@bmhcc.org
Received: October 6, 2021 Peer-review started: October 6, 2021 First decision: January 12, 2022 Revised: January 24, 2022 Accepted: February 27, 2022 Article in press: February 27, 2022 Published online: April 25, 2022 Processing time: 195 Days and 4.5 Hours
Core Tip
Core Tip: Acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with hypercoagulability. However, in this unique case, a patient suffered two separate thromboembolisms, one in the brachiocephalic artery and an ischemic stroke. With only two risk factors at baseline and no corresponding elevation in inflammatory markers, we hypothesize that the clots grew slowly over time which would not cause acutely elevated inflammatory markers. Although her SARS-CoV-2 infection occurred six months prior to her Emergency Department presentation, we hypothesize the hypercoagulable state caused by coronavirus disease 2019 was contributory. Additionally, it is unlikely the vaccination alone caused her thrombosis, yet it is still possible it had a contributory effect.
