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©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Pleomorphic cutaneous xanthomas disclosing homozygous familial hypercholesterolemia
Antonio Mastrolorenzo, Antonietta D’Errico, Department of Surgery and Translational Medicine, Section of Dermatology, University of Florence, Public Hospital Piero Palagi, Florence 50125, Italy
Piera Pierotti, Azienda Sanitaria di Firenze, Department of Infectious Diseases, Ospedale SM Annunziata, Florence 50012, Italy
Margherita Vannucchi, Histopathology and Molecular Diagnostics Institute, Careggi University Hospital, Florence 50134, Italy
Stefano Giannini, Diabetes and Metabolic Disease Agency, Careggi University Hospital, Florence 50134, Italy
Fiammetta Fossi, SODc of Transfusion Medicine and Cell Therapy, Careggi University Hospital, Florence 50134, Italy
Author contributions: Mastrolorenzo A and D’Errico A designed the report; Pierotti P performed the infectivology analyses; Mastrolorenzo A and D’Errico A collected the patient’s clinical data; Giannini S and Fossi F perfomed the vascular and metabolic analyses, dyspipidemia management and critical revision; Vannucchi M perfomed the histopathological analyses; Mastrolorenzo A and D’Errico A analyzed the data and wrote the paper.
Institutional review board statement: The Case Report was reviewed and approved by the (Department of Surgery and Translational Medicine, Section of Dermatology, University of Florence) Institutional Review Board as required.
Informed consent statement: The patient involved in this case report has signed an informed consent allowing the use of pictures and information in an anonymous format.
Conflict-of-interest statement: The authors have no conflicts of interest and have not received any funding or financial consideration with respect to this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Antonio Mastrolorenzo, MD, Department of Surgery and Translational Medicine, Section of Dermatology, University of Florence, Public Hospital Piero Palagi, Viale Michelangiolo 41, Florence 50125, Italy. amas@dada.it
Telephone: +39-055-6939655 Fax: +39-055-6939598
Received: July 12, 2017
Peer-review started: July 20, 2017
First decision: August 7, 2017
Revised: August 26, 2017
Accepted: October 15, 2017
Article in press: October 16, 2017
Published online: November 2, 2017
Processing time: 123 Days and 16.8 Hours
Peer-review started: July 20, 2017
First decision: August 7, 2017
Revised: August 26, 2017
Accepted: October 15, 2017
Article in press: October 16, 2017
Published online: November 2, 2017
Processing time: 123 Days and 16.8 Hours
Core Tip
Core tip: This article describes a contemporary approach to the differential diagnosis of xanthomas, and the morphological classification from a review of the literature, specifically reflect the clinical findings evidenced in this case report.