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©2014 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Anesthesiol. Mar 27, 2014; 3(1): 31-45
Published online Mar 27, 2014. doi: 10.5313/wja.v3.i1.31
Published online Mar 27, 2014. doi: 10.5313/wja.v3.i1.31
Perioperative care and cancer recurrence: Is there a connection?
Ashish K Khanna, Efrain Riveros Perez, Amanda Moraska, Cleveland Clinic Foundation, Cleveland, OH 44195, United States
Krzysztof Laudanski, Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA 19104, United States
Kenneth C Cummings III, Anesthesiology Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, United States
Author contributions: Khanna AK contributed to the design, initial organization and acquisition of data, formatting and final approval of the drafted manuscript; Perez ER, Laudanski K and Moraska A contributed to the acquisition of data, formatting and write up of the drafted manuscript; Cummings KC III contributed to the design, initial organization and acquisition of data, formatting and final approval of the drafted manuscript.
Correspondence to: Kenneth C Cummings III, MD, MS, Staff Anesthesiologist, Anesthesiology Institute, Cleveland Clinic Foundation, 9500, Euclid Avenue, E-30, Cleveland, OH 44195, United States. cummink2@ccf.org
Telephone: +1-216-4441016 Fax: +1-216-4444383
Received: October 21, 2013
Revised: January 27, 2014
Accepted: February 16, 2014
Published online: March 27, 2014
Processing time: 140 Days and 15.2 Hours
Revised: January 27, 2014
Accepted: February 16, 2014
Published online: March 27, 2014
Processing time: 140 Days and 15.2 Hours
Core Tip
Core tip: Cancer mortality is frequently related to metastatic disease. An altered balance between the tendency of the tumor to spread via metastasis and the body’s anti defense processes is the most plausible mechanism of cancer spread. This comprehensive review summarizes the role of anesthetic technique and perioperative interventions and their influence in cancer recurrence. An exhaustive compilation of the latest research and ongoing clinical trials in this area is presented to the reader.