Clinical results of linezolid in arthroplasty and trauma MRSA related infections

Table 1 Summary of patient management

Patient number	Age,yr	Sex	Organism	Category	CRP (Init-ial/final)	Surgical intervention	Number of surg-ical procedures	Linezolid duration (d)	Concurrent antibiotics	Previous antibiotics prior to linezolid	Follow-up (mo)	Resolution
1	43	M	MRSA	Post Trauma	301/< 5	Yes	2	14	Rifampicin	Vancomycin	57	Yes
2	47	F	MRSA	Non Trauma	148/9.8	Yes	2	28	No	Vancomycin	3	Yes
										Clarithromycin
3	43	M	MRSA	Non Trauma	235/9.8	No	0	84	No	N	14	Yes
4	80	F	Coag neg staph	Arthroplasty	30/< 5	Yes	2	28	No	Vancomycin	33	Yes
5	81	F	Coag Neg staph	Arthroplasty	134/39	Yes	1	42	Rifampicin	Vancomycin	25	Yes
6	20	M	MRSA	Post Trauma	146/< 5	Yes	5	28	No	Flucloxacillin	23	Yes
										Vancomycin
										Rifampicin
7	52	F	Staph aureus	Arthroplasty	133/54	Yes	3	28	No	Vancomycin	41	Yes
			Pseudomonas							Clindamycin
8	79	M	Staph epidermidis	Arthroplasty	153/15.5	Yes	2	28	Rifampicin	Vancomycin	20	Yes
			Coag Neg staph
			Coliforms
9	73	F	Coag Neg staph	Arthroplasty	106/46	Yes	2	28	No	Vancomycin	24	Yes
										Rifampicin
10	45	M	None identified	Post Trauma	129/< 5	Yes	2	28	No	Vancomycin	36	Yes
11	48	M	Coag Neg staph	Arthroplasty	79/15	Yes	6	28	No	Vancomycin	41	Yes
			Strep viridians
			Coliforms
			Acro Xylo
12	43	M	MRSA	Post Trauma	72/< 5	Yes	1	28	No	None	24	Yes
13	63	F	Staph aureus	Post Trauma	Sep-63	Yes	1	70	No	Vancomycin	6	Yes
14	47	M	MRSA	Post Trauma	124/12	Yes	4	42	No	Vancomycin	19	No
15	64	F	Staph aureus	Non Trauma	155/5.5	No	0	8	No	Vancomycin	RIP	No
			E. coli
			Enterococcus
16	83	F	Enterococcus	Arthroplasty	21/18.6	Yes	1	21	No	Vancomycin	39	No
17	73	M	Coag neg staph	Arthroplasty	68/< 5	Yes	1	28	No	Vancomycin	50	Yes
18	68	M	MRSA	Post Trauma	91/< 5	Yes	1	28	No	Vancomycin	18	Yes
			Group B strep
19	77	M	MRSA	Arthroplasty	65/62	Yes	4	28	No	Vancomycin	47	No
			Coliforms
			Gram negative bacillus
20	86	M	MRSA	Non Trauma	155/26	Yes	2	10	No	Vancomycin	6	Yes
										Rifampicin
21	79	M	Coag Neg staph	Arthroplasty	29/5	Yes	3	42	No	Vancomycin	22	No
										Rifampicin
22	35	M	Coag Neg staph	Post Trauma	64/< 5	Yes	3	42	No	Vancomycin	45	Yes

F: Female; M: male; MRSA: Methicillin resistant Staphylococcus aureus; CRP: C-reactive protein.