Dose of alendronate directly increases trabeculae expansivity without altering bone volume in rat femurs

Figure 1 Fracture made with a reciprocating saw. A: First, the bone is fixated with a plate and screws; B: Second, a fracture is induced with a reciprocating saw; C: Finally, the fractured femur is fixed.

Figure 2 Delimitation of the defect for analysis.

Figure 3 Regions of interest. A: Region of internal interest; B: Followed by region of external interest.

Figure 4 Region of internal interest of the femur, showing different patterns of trabeculae among groups. A; Group C: Control; B: Group B1: Bisphosphonate 1 mg/kg; C: Group B2: Bisphosphonate 3 mg/kg.

Figure 5 Region of internal interest of the femur, showing different patterns of trabeculae among groups. A: Group C: Control; B: Group B1: Bisphosphonate 1 mg/kg; C: Group B2: Bisphosphonate 3 mg/kg.