Systematic Reviews
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Dec 18, 2017; 8(12): 946-955
Published online Dec 18, 2017. doi: 10.5312/wjo.v8.i12.946
Antibiotic bone cement’s effect on infection rates in primary and revision total knee arthroplasties
Donald Kleppel, Jacob Stirton, Jiayong Liu, Nabil A Ebraheim
Donald Kleppel, Department of Medicine and Life Sciences, Toledo University, Toledo, OH 43614, United States
Jacob Stirton, Jiayong Liu, Nabil A Ebraheim, Department of Orthopedic Surgery, Medical Center, Toledo University, Toledo, OH 43614, United States
Author contributions: Kleppel D performed the research and analyzed the data; Stirton J, Liu J and Ebraheim NA provided structure for the article, edited and revised the paper; Kleppel D and Liu J wrote the paper; Stirton J and Ebraheim NA edited the paper.
Conflict-of-interest statement: The authors report no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jiayong Liu, MD, Assistant Professor, Department of Orthopedic Surgery, Medical Center, Toledo University, 3065 Arlington Avenue, Toledo, OH 43614, United States. jiayong.liu@utoledo.edu
Telephone: +1-800-5865336
Received: August 8, 2017
Peer-review started: August 9, 2017
First decision: September 4, 2017
Revised: September 13, 2017
Accepted: November 1, 2017
Article in press: November 1, 2017
Published online: December 18, 2017
Processing time: 132 Days and 1.7 Hours
Core Tip

Core tip: A systematic review and meta-analysis of randomized controlled trials/studies on primary and revision total knee arthroplasties (TKA) using antibiotic impregnated bone cement (AIBC). AIBC was found to lower infection rates in revision TKA procedures, but not in primary TKA procedures.