Copyright
©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Oct 18, 2017; 8(10): 770-776
Published online Oct 18, 2017. doi: 10.5312/wjo.v8.i10.770
Published online Oct 18, 2017. doi: 10.5312/wjo.v8.i10.770
Soft tissue swelling incidence using demineralized bone matrix in the outpatient setting
Kingsley R Chin, Charles E. Schmidt College of Medicine at Florida Atlantic University, Boca Raton, FL 33431, United States
Kingsley R Chin, Jason A Seale, Juan M Valdivia, Less Exposure Surgery Specialists Institute, Fort Lauderdale, FL 33311, United States
Kingsley R Chin, Herbert Wertheim College of Medicine at Florida International University, Miami, FL 33199, United States
Fabio J R Pencle, Jason A Seale, Juan M Valdivia, Less Exposure Surgery Society, Malden, MA 02148, United States
Author contributions: All authors contributed with drafting writing and final revision of manuscript; Pencle FJR performed statistical analysis; Valdivia JM provided independent assessment of pre and post op radiographs; Chin KR performed supervision and important critical revision.
Institutional review board statement: IRB approval was granted for patients involved in study from George Washington University as part of a cohort of patients who had anterior cervical surgery.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: We did not seek or receive any funding from the National Institutes of Health (NIH), Wellcome Trust, Howard Hughes Medical Institute (HHMI), or others for this work. Chin KR is a shareholder in and receives other benefits from SpineFrontier Inc.; none of the other authors (Pencle FJR, Valdivia JM and Seale JA) have any potential conflicts of interest to declare for this work.
Data sharing statement: This dataset available from the corresponding author at Dryad repository, who will provide a permanent, citable and open-access home for the dataset.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Fabio JR Pencle, Research Fellow, Less Exposure Surgery Society, 350 Main Street, Malden, MA 02148, United States. fabiopencle@thelessinstitute.com
Telephone: +1-954-6406010 Fax: +1-855-4114647
Received: February 21, 2017
Peer-review started: February 26, 2017
First decision: July 10, 2017
Revised: July 28, 2017
Accepted: August 15, 2017
Article in press: August 16, 2017
Published online: October 18, 2017
Processing time: 238 Days and 9.1 Hours
Peer-review started: February 26, 2017
First decision: July 10, 2017
Revised: July 28, 2017
Accepted: August 15, 2017
Article in press: August 16, 2017
Published online: October 18, 2017
Processing time: 238 Days and 9.1 Hours
Core Tip
Core tip: This manuscript scientifically assesses prevertebral swelling with the use of demineralized bone matrix (DBM) anterior to cervical cage. The use of clinical and radiographic outcomes demonstrates the safety of DBM in the outpatient setting. There are no studies showing safety or outcomes of DBM anterior to the cage and directly exposed to the pre vertebral soft tissues therefore we wanted to document this study.