Editorial
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Sep 18, 2015; 6(8): 577-589
Published online Sep 18, 2015. doi: 10.5312/wjo.v6.i8.577
Aetiology and mechanisms of injury in medial tibial stress syndrome: Current and future developments
Melanie Franklyn, Barry Oakes
Melanie Franklyn, Department of Mechanical Engineering, the University of Melbourne, Parkville, VIC 3010, Australia
Barry Oakes, Cheltenham Sports Medicine Clinic, Cheltenham, Melbourne, VIC 3192, Australia
Author contributions: Both authors contributed to this manuscript.
Conflict-of-interest statement: Both authors, Dr. Melanie Franklyn and Associate Professor Barry Oakes, declare that there is no conflict of interest for this work. They have received no funds from any commercial party in relation to this work.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Melanie Franklyn, PhD, Department of Mechanical Engineering, the University of Melbourne, Engineering Block E Building Level 4, Parkville, VIC 3010, Australia. melanief@unimelb.edu.au
Telephone: +61-3-96267171 Fax: +61-3-96267830
Received: March 31, 2015
Peer-review started: April 4, 2015
First decision: April 27, 2015
Revised: July 1, 2015
Accepted: July 24, 2015
Article in press: July 27, 2015
Published online: September 18, 2015
Processing time: 171 Days and 3.9 Hours
Core Tip

Core tip: Medial tibial stress syndrome (MTSS) is an overuse injury characterised by diffuse tibial anteromedial or posteromedial surface subcutaneous periostitis, usually in conjunction with underlying cortical bone microtrauma. Nuclear bone scans or magnetic resonance imaging findings need to be considered in conjunction with clinical symptoms and patient history for an accurate diagnosis. Compared to exercising controls, MTSS patients have low bone mineral density and low values of a number of tibial cortical bone geometric parameters such a cross-sectional area. Recent research includes the development of computational models for studying tibial stress injuries. These models offer a tool to study the exact causes of MTSS, which are still unknown.