Copyright
©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Nov 18, 2014; 5(5): 694-698
Published online Nov 18, 2014. doi: 10.5312/wjo.v5.i5.694
Published online Nov 18, 2014. doi: 10.5312/wjo.v5.i5.694
Vanishing bone disease (Gorham-Stout syndrome): A review of a rare entity
Vasileios S Nikolaou, Dimitrios Chytas, Nicolas Efstathopoulos, 2nd Orthopaedic Department, School of Medicine, Athens University, 15124 Athens, Greece
Demitrios Korres, Orthopaedic Department, Athens University, 15124 Athens, Greece
Author contributions: Nikolaou VS and Chytas D contributed equally to this work and performed the literature research and wrote the paper; Korres D provided the pictures and the history of the case example; Efstathopoulos N did the final proof reading of the paper and made final corrections.
Correspondence to: Vasileios S Nikolaou, MD, PhD, MSc, Orthopaedic Surgeon, Lecturer in Orthopaedics, 2nd Orthopaedic Department, School of Medicine, Athens University, Dimitriou Ralli 21 Street, Maroussi, 15124 Athens,Greece. vassilios.nikolaou@gmail.com
Telephone: +30-69-32543400 Fax: +30-21-08022142
Received: February 11, 2014
Revised: March 30, 2014
Accepted: May 31, 2014
Published online: November 18, 2014
Processing time: 190 Days and 15.7 Hours
Revised: March 30, 2014
Accepted: May 31, 2014
Published online: November 18, 2014
Processing time: 190 Days and 15.7 Hours
Core Tip
Core tip: Vanishing bone disease (Gorham-Stout syndrome) is a rare entity of unknown etiology, characterized by destruction of osseous matrix and proliferation of vascular structures, resulting in destruction and absorption of bone. The syndrome can affect one or multiple bones of the patient, including the skull, the upper and lower extremities, the spine and pelvis. Physicians should be aware of the existence of this rare entity and reliably direct affected patients to right diagnosis and therapeutic approach.