Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Mar 18, 2024; 15(3): 204-214
Published online Mar 18, 2024. doi: 10.5312/wjo.v15.i3.204
Update on the use of 45S5 bioactive glass in the treatment of bone defects in regenerative medicine
Dayane Maria Braz Nogueira, Marcelie Priscila de Oliveira Rosso, Daniela Vieira Buchaim, Mariana Schutzer Ragghianti Zangrando, Rogério Leone Buchaim
Dayane Maria Braz Nogueira, Mariana Schutzer Ragghianti Zangrando, Department of Prosthodontics and Periodontics, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, Brazil
Marcelie Priscila de Oliveira Rosso, Rogério Leone Buchaim, Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, Brazil
Daniela Vieira Buchaim, Medical School, University Center of Adamantina, Adamantina 17800-000, Brazil
Daniela Vieira Buchaim, Postgraduate Program in Structural and Functional Interactions in Rehabilitation, Postgraduate Department, University of Marília, Marília 17525-902, Brazil
Author contributions: Nogueira DMB and Rosso MPO contributed equally to this work; Buchaim DV and Buchaim RL designed the research study; Nogueira DMB and Rosso MPO performed the research; Zangrando analyzed the data; Nogueira DMB, Rosso MPO and Buchaim RL wrote the manuscript; all authors have read and approve the final manuscript.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rogério Leone Buchaim, PhD, Associate Professor, Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octávio Pinheiro Brisolla 9-75, Bauru 17012-901, Brazil. rogerio@fob.usp.br
Received: November 16, 2023
Peer-review started: November 16, 2023
First decision: December 29, 2023
Revised: January 15, 2024
Accepted: February 1, 2024
Article in press: February 1, 2024
Published online: March 18, 2024
Processing time: 119 Days and 14.8 Hours
Core Tip

Core Tip: Regenerative medicine demands materials with effective osteoconductive and bioactive properties. Compared with other materials, 45S5 bioactive glass not only exhibits more biocompatibility but also enhances bone growth when combined with composites. Moreover, its antimicrobial properties offer many possibilities for future applications.