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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Nov 18, 2024; 15(11): 1007-1014
Published online Nov 18, 2024. doi: 10.5312/wjo.v15.i11.1007
Published online Nov 18, 2024. doi: 10.5312/wjo.v15.i11.1007
Cardiotoxicity concerns in total joint arthroplasty
Chun-Han Cheng, Department of Medical Education, Linkou Chang Gung Memorial Hospital, Taoyuan City 33305, Taiwan
Wen-Rui Hao, Division of Cardiology, Department of Internal Medicine, Shuang Ho Hospital, Ministry of Health and Welfare, Taipei Medical University, New Taipei City 23561, Taiwan
Wen-Rui Hao, Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11002, Taiwan
Tzu-Hurng Cheng, Department of Biochemistry, School of Medicine, College of Medicine, China Medical University, Taichung City 404328, Taiwan
Co-first authors: Chun-Han Cheng and Wen-Rui Hao.
Author contributions: Cheng CH and Hao WR contribute equally to this study as co-first authors. Cheng CH and Hao WR primarily responsible for writing; Cheng TH overseeing revisions; all authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors declare having no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tzu-Hurng Cheng, PhD, Professor, Department of Biochemistry, School of Medicine, College of Medicine, China Medical University, No. 91 Xueshi Road, North District, Taichung City 404328, Taiwan. thcheng@mail.cmu.edu.tw
Received: August 7, 2024
Revised: September 26, 2024
Accepted: October 22, 2024
Published online: November 18, 2024
Processing time: 99 Days and 20.8 Hours
Revised: September 26, 2024
Accepted: October 22, 2024
Published online: November 18, 2024
Processing time: 99 Days and 20.8 Hours
Core Tip
Core Tip: This editorial discusses the findings of the study of Brennan et al on the cardiotoxic effects of elevated metal concentrations in patients receiving total joint arthroplasty. Increased cobalt and titanium levels are associated with substantial changes in the cardiac structure and function. Emphasizing the importance of monitoring metal ion levels, this editorial underscores that further research should be conducted to im