Meta-Analysis
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Jun 18, 2023; 14(6): 485-501
Published online Jun 18, 2023. doi: 10.5312/wjo.v14.i6.485
Effectiveness of platelet-rich plasma in the treatment of Achilles tendon disease
Dan Huang, Djandan Tadum Arthur Vithran, Hao-Li Gong, Ming Zeng, Zhong-Wen Tang, Zhou-Zhou Rao, Jie Wen, Sheng Xiao
Dan Huang, Hao-Li Gong, Ming Zeng, Zhong-Wen Tang, Jie Wen, Sheng Xiao, Department of Pediatric Orthopedics, Hunan Provincial People’s Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha 410013, Hunan Province, China
Djandan Tadum Arthur Vithran, Department of Orthopaedics, Xiangya Hospital of Central South University, Changsha 410013, Hunan Province, China
Zhou-Zhou Rao, Department of Physiology, Hunan Normal University School of Medicine, Changsha 410005, Hunan Province, China
Jie Wen, Department of Anatomy, Hunan Normal University School of Medicine, Changsha 410005, Hunan Province, China
Author contributions: Huang D, Arthur Vithran DT and Gong HL contribute equally to this study, they share co-first author; Wen J conceived and coordinated the study, designed; Xiao S performed and analyzed the experiments; Tang ZW wrote the paper; Zeng M, Arthur Vithran DT and Gong HL did the data analysis and carried out the data collection; Zeng M revised the paper; and all authors approved the final version of the manuscript.
Supported by Scientific Research Project of Hunan Education Department, No. 21B0031 and No. 21B0042.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jie Wen, PhD, Associate Professor, Department of Pediatric Orthopedics, Hunan Provincial People’s Hospital, The First Affiliated Hospital of Hunan Normal University, No. 61 West Jiefang Road, Changsha 410013, Hunan Province, China. cashwj@qq.com
Received: December 24, 2022
Peer-review started: December 24, 2022
First decision: March 28, 2023
Revised: March 28, 2023
Accepted: April 20, 2023
Article in press: April 20, 2023
Published online: June 18, 2023
Core Tip

Core Tip: Achilles tendon rupture (ATR) and Achilles tendinopathy (AT) are commonly seen in orthopaedic outpatient clinics. The effectiveness of Platelet-Rich Plasma in the treatment of patients with ATR and AT has been controversial. This study aims to inform the decisions of physicians faced with challenges when making treatment choices.