Systematic Reviews
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Jun 18, 2023; 14(6): 458-470
Published online Jun 18, 2023. doi: 10.5312/wjo.v14.i6.458
Cost-effectiveness of patient specific vs conventional instrumentation for total knee arthroplasty: A systematic review and meta-analysis
Isobel M Dorling, Lars Geenen, Marion J L F Heymans, Jasper Most, Bert Boonen, Martijn G M Schotanus
Isobel M Dorling, Lars Geenen, Marion J L F Heymans, Jasper Most, Bert Boonen, Martijn G M Schotanus, Department of Orthopaedic Surgery and Traumatology, Zuyderland Medical Center, Sittard-Geleen 6162 BG, Limburg, Netherlands
Marion J L F Heymans, Zuyderland Academy, Zuyderland Medical Center, Sittard-Geleen 6155 NH, Limburg, Netherlands
Jasper Most, Martijn G M Schotanus, School of Care and Public Health Research Institute (CAPHRI), Faculty of Health, Medicine and Life Sciences, Maastricht 6229 ER, Limburg, Netherlands
Martijn G M Schotanus, Department of Orthopaedic Surgery and Traumatology, Maastricht University Medical Center, Maastricht 6229 HX, Limburg, Netherlands
Author contributions: Dorling IM designed the research; Dorling IM and Geenen L performed the research; Heymans MJLF performed the systematic search; Dorling IM and Geenen L performed the data analysis; Most J, Boonen B, and Schotanus MGM supervised the research and revised the manuscript; Dorling IM wrote the paper.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Martijn G M Schotanus, BSc, MSc, PhD, Postdoc, Senior Researcher, Department of Orthopaedic Surgery and Traumatology, Zuyderland Medical Center, dr. H vd Hoffplein 1, Sittard-Geleen 6162 BG, Limburg, Netherlands. m.schotanus@zuyderland.nl
Received: December 21, 2022
Peer-review started: December 21, 2022
First decision: April 13, 2023
Revised: April 26, 2023
Accepted: May 15, 2023
Article in press: May 15, 2023
Published online: June 18, 2023
Processing time: 179 Days and 11.2 Hours
Core Tip

Core Tip: Patient specific instrumentation (PSI) for total knee arthroplasty (TKA) has become a frequently used technique for performing TKA. In the past decade the use of PSI TKA has not proven superior nor inferior when compared to conventional instrumentation (CI) for TKA in terms of prosthetic alignment, prosthetic survival, and patient satisfaction. However, PSI TKA has been associated with a higher healthcare cost. In this review, we critically analysed the cost of PSI TKA compared to CI TKA, focusing on all facets of their cost.