Roberts S, Arshad A, Tsirikos AI. Surgical and long-term functional outcomes of patients with Duchenne muscular dystrophy following spinal deformity correction. World J Orthop 2023; 14(6): 411-426 [PMID: 37377990 DOI: 10.5312/wjo.v14.i6.411]
Corresponding Author of This Article
Athanasios I Tsirikos, FRCS, MD, PhD, Senior Lecturer, Surgeon, Scottish National Spine Deformity Centre, Royal Hospital for Children and Young People, 50 Little France Crescent, Edinburgh Bioquarter, Edinburgh EH16 4TJ, United Kingdom. thanos.tsirikos@nhslothian.scot.nhs.uk
Research Domain of This Article
Orthopedics
Article-Type of This Article
Retrospective Cohort Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Orthop. Jun 18, 2023; 14(6): 411-426 Published online Jun 18, 2023. doi: 10.5312/wjo.v14.i6.411
Surgical and long-term functional outcomes of patients with Duchenne muscular dystrophy following spinal deformity correction
Simon Roberts, Ayesha Arshad, Athanasios I Tsirikos
Simon Roberts, Department of Spinal Surgery, Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, United Kingdom
Ayesha Arshad, Athanasios I Tsirikos, Scottish National Spine Deformity Centre, Royal Hospital for Children and Young People, Edinburgh EH16 4TJ, United Kingdom
Author contributions: Tsirikos AI was the guarantor, treated the patients, designed the study, participated in acquisition, analysis and interpretation of the data and drafted the manuscript; Arshad A and Roberts S participated in analysis and interpretation of the data and drafted the manuscript.
Institutional review board statement: This retrospective cohort study does not require ethical review.
Informed consent statement: The requirement for a signed informed consent was waived.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Athanasios I Tsirikos, FRCS, MD, PhD, Senior Lecturer, Surgeon, Scottish National Spine Deformity Centre, Royal Hospital for Children and Young People, 50 Little France Crescent, Edinburgh Bioquarter, Edinburgh EH16 4TJ, United Kingdom. thanos.tsirikos@nhslothian.scot.nhs.uk
Received: December 27, 2022 Peer-review started: December 27, 2022 First decision: March 14, 2023 Revised: March 29, 2023 Accepted: May 15, 2023 Article in press: May 15, 2023 Published online: June 18, 2023 Processing time: 173 Days and 14.7 Hours
Core Tip
Core Tip: Duchenne muscular dystrophy (DMD) patients develop progressive spinal deformity after loss of independent ambulation. There is limited data on the effect of spinal deformity correction on long-term functional outcomes or satisfaction in DMD patients. This retrospective cohort study investigated long-term functional outcomes following spinal deformity correction in DMD patients, reporting clinical, surgical, radiographic and functional outcomes. All patients were satisfied with surgical outcomes at long-term follow-up. Surgical correction of spinal deformity can have favourable long-term effects on quality of life (QoL) in DMD patients. These results support surgical correction of spinal deformity to improve long-term QoL in DMD patients with spinal deformity.
