Retrospective Cohort Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Apr 18, 2023; 14(4): 218-230
Published online Apr 18, 2023. doi: 10.5312/wjo.v14.i4.218
Clinical outcomes of cemented distal femur replacements with all-polyethylene tibial components for oncologic indications
Alexander B Christ, Brian C Chung, Matthew Urness, Lucas W Mayer, Brandon S Gettleman, Nathanael D Heckmann, Lawrence R Menendez
Alexander B Christ, Brian C Chung, Matthew Urness, Lucas W Mayer, Nathanael D Heckmann, Lawrence R Menendez, Department of Orthopedic Surgery, Keck School of Medicine of University of Southern California, Los Angeles, CA 90033, United States
Brandon S Gettleman, University of South Carolina School of Medicine, Columbia, SC 29209, United States
Author contributions: Christ AB, Menendez LR, and Heckmann ND generated the idea, provided guidance throughout, were heavily involved in copy-editing, and oversaw execution of the project; Chung BC, Urness M, Mayer L, and Gettleman BS were responsible for data collection, literature review, statistical analysis, and drafting the manuscript; All authors listed read and approved the final manuscript.
Institutional review board statement: Proposal #HS-20-00396 indicates that this study is determined to be IRB exempt.
Informed consent statement: The study is IRB-exempt at our institution because we did not employ the use of humans and the use of their protected health information for this study was deemed minimal risk. Thus, an Informed Consent form is not applicable for this study.
Conflict-of-interest statement: One of the authors (N.D.H.) is a paid consultant for Intellijoint Surgical and MicroPort Orthopedics, has stock options from Intellijoint Surgical, and is a committee member of AAOS and AJRR. One of the authors (L.R.M.) is a paid consultant for Onkos Surgical and receives IP royalties from TeDan Surgical. Each author certifies that he has no commercial associations that might pose a conflict of interest in connection with the submitted article. One of the authors (A.B.C) is a board member for AAOS, Musculoskeletal Tumor Society, Orthopaedic Society. (A.B.C) is also a paid consultant for Smith and Nephew, Intellijoint Surgical, and Enovis.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement – checklist of items, and the manuscript was prepared and revised according to the STROBE Statement – checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Alexander B Christ, MD, Doctor, Department of Orthopedic Surgery, Keck School of Medicine of University of Southern California, 1500 San Pablo Street, Los Angeles, CA 90033, United States. alexander.b.christ@gmail.com
Received: January 13, 2023
Peer-review started: January 13, 2023
First decision: February 2, 2023
Revised: February 10, 2023
Accepted: April 4, 2023
Article in press: April 4, 2023
Published online: April 18, 2023
Processing time: 95 Days and 8.1 Hours
Core Tip

Core Tip: The current study demonstrates modest short-term survivorship following cemented distal femoral replacement with all-polyethylene tibial components for oncologic indications. Approximately one third of patients experienced a postoperative complication. The most common modes of implant failure were soft tissue failure and endoprosthetic infection.