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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Jun 18, 2022; 13(6): 578-586
Published online Jun 18, 2022. doi: 10.5312/wjo.v13.i6.578
Published online Jun 18, 2022. doi: 10.5312/wjo.v13.i6.578
Reducing bacterial adhesion to titanium surfaces using low intensity alternating electrical pulses
Marti Bernaus, Margarita Veloso, Lluís Font-Vizcarra, Department of Orthopedics and Traumatology, Osteoarticular Infection Unit, Hospital Universitari Mutua Terrassa, Terrassa 08221, Spain
Jordi Guillem-Marti, Department of Materials Science and Metallurgical Engineering, Universitat Politecnica de Catalunya, Barcelona 08930, Spain
Jordi Guillem-Marti, Barcelona Research Center in Multiscale Science and Engineering, Universitat Politecnica de Catalunya, Barcelona 08930, Spain
Adrian Bermúdez-Castel, Lluís Font-Vizcarra, Innovative Minds, S.L., Terrassa 08224, Spain
Jose Antonio Calero, Diego Torres, AMES PM Tech Center, Sant Vicenç dels Horts 08980, Spain
Author contributions: Bernaus M, Guillem-Martí J, and Font-Vizcarra L have made substantial contributions to research design, acquisition, analysis, interpretation of data, and drafting the manuscript; Bermúdez A, Calero JA, Torres D, and Veloso M have made substantial contributions to interpretation of data and critically revising the manuscript; All authors have read and approved the final submitted manuscript.
Conflict-of-interest statement: Each author certifies that he or she has no commercial associations (e.g., consultancies, stock ownership, equity interest, patent/Licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Marti Bernaus, MD, Surgeon, Department of Orthopedics and Traumatology, Osteoarticular Infection Unit, Hospital Universitari Mutua Terrassa, Plaça Dr. Robert 5, Terrassa 08221, Spain. mbernaus@mutuaterrassa.cat
Received: December 25, 2021
Peer-review started: December 25, 2021
First decision: March 7, 2022
Revised: March 20, 2022
Accepted: May 22, 2022
Article in press: May 22, 2022
Published online: June 18, 2022
Processing time: 173 Days and 16.5 Hours
Peer-review started: December 25, 2021
First decision: March 7, 2022
Revised: March 20, 2022
Accepted: May 22, 2022
Article in press: May 22, 2022
Published online: June 18, 2022
Processing time: 173 Days and 16.5 Hours
Core Tip
Core Tip: Current strategies to prevent orthopedic implant infections have focused on chemical measures. Our data suggest electrical currents may be useful in preventing Staphylococcus aureus and Escherichia coli adhesion to titanium surfaces. Reduction in adhesion rates of up to 90% were observed when applying low intensity alternating currents on titanium surfaces. Further research is needed to consider the use of electrical currents for infection prevention in an in vivo scenario.