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World J Orthop. Jun 18, 2022; 13(6): 564-573
Published online Jun 18, 2022. doi: 10.5312/wjo.v13.i6.564
Managements of osteoporotic vertebral compression fractures: A narrative review
Devon Patel, Jiayong Liu, Nabil A Ebraheim
Devon Patel, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, United States
Jiayong Liu, Nabil A Ebraheim, Department of Orthopedic Surgery, University of Toledo Medical Center, Toledo, OH 43614, United States
Author contributions: Liu J and Ebraheim NA designed the research study; Patel D performed the data collection; Patel D, Liu J, and Ebraheim NA analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Conflict-of-interest statement: All authors declare that they have no conflicts of interest in creating and publishing this manuscript and received no funding to assist in its completion.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jiayong Liu, MD, Associate Professor, Department of Orthopedic Surgery, University of Toledo Medical Center, 3065 Arlington Avenue, Toledo, OH 43614, United States. jiayong.liu@utoledo.edu
Received: February 28, 2022
Peer-review started: February 28, 2022
First decision: April 13, 2022
Revised: April 26, 2022
Accepted: June 14, 2022
Article in press: June 14, 2022
Published online: June 18, 2022
Processing time: 108 Days and 7 Hours
Core Tip

Core Tip: Management of osteoporotic vertebral compression fractures must be combined with multiple approaches. Appropriate exercises and activity modification are important in fracture prevention. Medication with different mechanisms of action is a critical long-term causal treatment strategy. The minimally invasive surgical interventions such as vertebroplasty and kyphoplasty are reserved for patients not responsive to conservative therapy and are recognized as efficient stopgap treatment methods. Posterior decompression and fixation or Anterior decompression and reconstruction may be required if neurological deficits are present.