Editorial
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Nov 18, 2022; 13(11): 949-954
Published online Nov 18, 2022. doi: 10.5312/wjo.v13.i11.949
Genetics of congenital anomalies of the hand
Zisis Kyriazis, Panagoula Kollia, Ioanna Grivea, Sotirios Sotiriou, Zoe H Dailiana
Zisis Kyriazis, Zoe H Dailiana, Department of Orthopaedic Surgery, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa 41500, Greece
Panagoula Kollia, Department of Genetics and Biotechnology, Faculty of Biology, National and Kapodistrian University of Athens, Athens 10679, Greece
Ioanna Grivea, Department of Paediatrics, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa 41500, Greece
Sotirios Sotiriou, Laboratory of Histology and Embryology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa 41500, Greece
Author contributions: Kyriazis Z wrote the paper and participated in the analysis and drafting of the literature data; Kollia P participated in the conception and design of the study, analysis and interpretation of the literature data, and critical revision of the article; Grivea I and Sotiriou S participated in analysis and interpretation of the literature data and critical revision of the article; Dailiana ZH participated in the conception and design of the study, analysis and interpretation of the literature data, and drafting and critical revision of the article; all authors actively reviewed and revised the manuscript and approved the finally submitted manuscript.
Conflict-of-interest statement: All the authors have no conflict of interest related to the manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zoe H Dailiana, MD, PhD, Professor, Surgeon, Department of Orthopaedic Surgery, Faculty of Medicine, School of Health Sciences, University of Thessaly, No. 3 Panepistimiou Street, Biopolis, Larissa 41500, Greece. dailiana@med.uth.gr
Received: August 29, 2022
Peer-review started: August 29, 2022
First decision: September 26, 2022
Revised: October 9, 2022
Accepted: October 14, 2022
Article in press: October 14, 2022
Published online: November 18, 2022
Processing time: 78 Days and 16.4 Hours
Core Tip

Core Tip: The genetic basis of hand disorders is elucidated by the expansion of knowledge and introduction of molecular analysis techniques which contribute to the identification of new genes responsible for them. New genes and mutations are being isolated and correlated with the disorder based on the advances in sequencing technology, such as next generation sequencing and genetic consultation, and future therapeutic developments are enhanced. There appears to be a gap in the literature concerning the knowledge about the genetic basis of all hand disorders. The current molecular status of them is discussed and a summary of different genes, already identified or suspected to be related with them, is presented.