Case Control Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Oct 18, 2021; 12(10): 751-759
Published online Oct 18, 2021. doi: 10.5312/wjo.v12.i10.751
SARS-CoV-2 outbreak impact on a trauma unit
Sarah Mills, Aitor Ibarzábal-Gil, José M Martínez-Diez, Javier Pallarés-Sanmartín, Carlos Kalbakdij-Sánchez, Juan C Rubio-Suárez, Itsaso Losantos-García, E Carlos Rodríguez-Merchán
Sarah Mills, Aitor Ibarzábal-Gil, José M Martínez-Diez, Javier Pallarés-Sanmartín, Carlos Kalbakdij-Sánchez, Juan C Rubio-Suárez, E Carlos Rodríguez-Merchán, Department of Orthopedic Surgery, La Paz University Hospital, Madrid, Spain
Itsaso Losantos-García, Department of Biostatistics, La Paz University Hospital, Madrid 28046, Spain
E Carlos Rodríguez-Merchán, Osteoarticular Surgery Research, Hospital La Paz Institute for Health Research – IdiPAZ (La Paz University Hospital – Autonomous University of Madrid), Madrid, Spain
Author contributions: Mills S was the author primarily responsible for the writing of the text; Rubio-Suárez JC and Rodríguez-Merchán EC assisted in the writing and editing of the text; the other authors provided critical expertise and input into the subject matter of the text.
Institutional review board statement: The study was approved by our Hospital’s Ethics Committee (La Paz University Hospital, Madrid, Spain).
Informed consent statement: All patients of this study signed an “informed consent” before surgery.
Conflict-of-interest statement: The authors have nothing to declare.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: E Carlos Rodríguez-Merchán, MD, PhD, Doctor, Department of Orthopedic Surgery, La Paz University Hospital, Paseo de la Castellana, 261, Spain. ecrmerchan@hotmail.com
Received: March 24, 2021
Peer-review started: March 24, 2021
First decision: June 16, 2021
Revised: June 17, 2021
Accepted: August 18, 2021
Article in press: August 18, 2021
Published online: October 18, 2021
Core Tip

Core Tip: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection was not a criterion for choosing conservative treatment, unless those patients infected with the virus had a poor general condition that made surgery unadvisable. We did not find a relationship between the employment of anticoagulant therapy and the severity of coronavirus disease 2019 (COVID-19) infection or a different mortality rate. Patients who died during hospitalization due to COVID-19 had higher C-reactive protein levels (P < 0.001) and higher urea levels (P = 0.006). The mortality rate in 2020 was 13.7% during hospitalization; 19% during the first month after discharge, and 24.6% in the 3 mo after discharge. The mortality rate in the COVID-19 positive patient subgroup was 38.9% after 6 mo of follow-up. Non-operative treatment in hip fractures was related to SARS-CoV-2 infection (P = 0.03) and with AO 31.B fractures. Polytrauma patients and high energy fractures were more common in 2019 (24%) than in 2020 (11.5%). The main difference between both periods was the injury mechanism.