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World J Orthop. Oct 18, 2021; 12(10): 743-750
Published online Oct 18, 2021. doi: 10.5312/wjo.v12.i10.743
Surgical treatment of metastatic bone disease of the distal extremities
Jennifer Sebghati, Pendar Khalili, Panagiotis Tsagkozis
Jennifer Sebghati, Medical School, Karolinska Institute, Solna 17177, Sweden
Pendar Khalili, Department of Orthopedics, Central Hospital in Karlstad, Karlstad 65230, Sweden
Panagiotis Tsagkozis, Department of Orthopedic Surgery, Karolinska University hospital, Solna 17176, Sweden
Panagiotis Tsagkozis, Department of Molecular Medicine and Surgery, Karolinska Institutet, Solna 17176, Sweden
Author contributions: Sebghati J, Khalili P and Tsagkozis P performed the literature searches, and contributed intellectual efforts and to the writing of the manuscript.
Conflict-of-interest statement: There are no conflicts of interest associated with any of the authors who contributed to the manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jennifer Sebghati, BMed, Research Scientist, Medical School, Karolinska Institute, Nobels väg 6, Solna 17177, Sweden. jennifer.sebghati@stud.ki.se
Received: February 25, 2021
Peer-review started: February 25, 2021
First decision: May 3, 2021
Revised: May 16, 2021
Accepted: August 6, 2021
Article in press: August 6, 2021
Published online: October 18, 2021
Processing time: 230 Days and 8.7 Hours
Core Tip

Core Tip: Metastatic bone disease distal to the elbow and knee is rare, often encountered in patients with spread cancer. Limb-preserving surgery is often possible in the lower arm and leg, and osteosynthesis with plate and screws or intramedullary nails are the most common surgical methods. In the lesions of the ankle, hand and foot, amputation is often utilized.