Chaganty SS, James D. Bilateral sequential femoral neck stress fractures in young adult with HIV infection on antiretroviral therapy: A case report. World J Orthop 2019; 10(6): 247-254 [PMID: 31259148 DOI: 10.5312/wjo.v10.i6.247]
Corresponding Author of This Article
Saisunder Shashank Chaganty, MBBS, Medical Student, Faculty of Medicine and Dentistry, University of Plymouth, John Bull Building, 16 Research Way, Plymouth Science Park, Plymouth PL6 8BU, United Kingdom. saisunder.chaganty@students.plymouth.ac.uk
Research Domain of This Article
Orthopedics
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Orthop. Jun 18, 2019; 10(6): 247-254 Published online Jun 18, 2019. doi: 10.5312/wjo.v10.i6.247
Bilateral sequential femoral neck stress fractures in young adult with HIV infection on antiretroviral therapy: A case report
Saisunder Shashank Chaganty, Deeptiman James
Saisunder Shashank Chaganty, Faculty of Medicine and Dentistry, University of Plymouth, Plymouth PL6 8BU, United Kingdom
Deeptiman James, Assistant Professor, Department of Orthopedics, Christian Medical College, Vellore, Vellore 632004, Tamil Nadu, India
Author contributions: Chaganty SS and James D contributed equally to this work; Deeptiman J designed methodology and provided patient data; Chaganty SS performed literature review; and Chaganty SS and Deeptiman J analysed literature and wrote the manuscript.
Informed consent statement: The patient provided informed written consent.
Conflict-of-interest statement: All authors have no conflicts of interest to report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Saisunder Shashank Chaganty, MBBS, Medical Student, Faculty of Medicine and Dentistry, University of Plymouth, John Bull Building, 16 Research Way, Plymouth Science Park, Plymouth PL6 8BU, United Kingdom. saisunder.chaganty@students.plymouth.ac.uk
Telephone: +0044-7952831648
Received: January 25, 2019 Peer-review started: January 25, 2019 First decision: March 14, 2019 Revised: April 13, 2019 Accepted: May 21, 2019 Article in press: May 23, 2019 Published online: June 18, 2019 Processing time: 143 Days and 5.5 Hours
Core Tip
Core tip: Stress fractures of the femoral neck among young adults are extremely rare. They usually result from either fatigue or predisposing conditions that give rise to weakened bones. We present a case of bilateral sequential femoral neck stress fractures in a young adult with human immunodeficiency virus (HIV) infection on antiretroviral therapy (ART) in the absence of comorbidities. Several mechanisms of HIV/ART induced osteopenia and osteoporosis are indicated to have played a role in predisposing our case towards such a presentation. Our case study adds to the paucity of evidence exploring the association between HIV/ART and reduced bone mineral density. Our case highlights the need for screening and prophylactic treatment for osteopenia and osteoporosis coexisting with HIV infection and ART.
