Prospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Feb 18, 2024; 15(2): 156-162
Published online Feb 18, 2024. doi: 10.5312/wjo.v15.i2.156
High rate of clinically relevant improvement following anatomical total shoulder arthroplasty for glenohumeral osteoarthritis
Marc Randall Kristensen Nyring, Bo Sanderhoff Olsen, Alexander Amundsen, Jeppe Vejlgaard Rasmussen
Marc Randall Kristensen Nyring, Bo Sanderhoff Olsen, Alexander Amundsen, Jeppe Vejlgaard Rasmussen, Section for Shoulder and Elbow Surgery, Department of Orthopaedic Surgery, Herlev and Gentofte University Hospital, Hellerup 2900, Denmark
Author contributions: Nyring MRK contributed to data collection, design of the study, data analysis, and draft of manuscript; Olsen BS contributed to design of the study and review of manuscript; Amundsen A contributed to data collection, review of manuscript; Rasmussen JV contributed to design of the study and review of manuscript; and all authors have read and approve the final manuscript.
Institutional review board statement: The study is conducted according to the ethics outlined in the Helsinki Declaration. A permission to handle and store data has been obtained from the Danish Data Protection Agency (No. 2012-58-0004). The study was evaluated by the regional Research Ethics Committee and it was decided that the study did not need approval (No. H-17003344). All patients have given informed consent prior to participation. The Ethics Committee/Institutional Review Board is from “Region Hovedstaden”. “Region Hovedstaden” is the overall organization that manages all hospitals in the capital region of Denmark, including Herlev and Gentofte Hospital, to which the authors are affiliated.
Informed consent statement: Due to Danish regulations, written consent was not necessary since the treatment was the standard treatment at the hospital, just with extra follow-up visits. However, all patients have given informed oral consent to participation.
Conflict-of-interest statement: The authors Bo S Olsen, Alexander Amundsen, and Jeppe V Rasmussen received institutional support for conducting the study “Functional outcome and complications after Global Unite prostheses” which provided data for the present study. In addition, Bo S Olsen and Jeppe V Rasmussen are paid speakers for DePuy Synthes (Raynham, Massachusetts, United States of America).
Data sharing statement: Data will be made available on reasonable request.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Marc Randall Kristensen Nyring, MD, Doctor, Researcher, Section for Shoulder and Elbow Surgery, Department of Orthopaedic Surgery, Herlev and Gentofte University Hospital, 12 Gentofte Hospitalsvej, Hellerup 2900, Denmark. marcrandallkristensen@gmail.com
Received: October 4, 2023
Peer-review started: October 4, 2023
First decision: December 12, 2023
Revised: December 20, 2023
Accepted: January 8, 2024
Article in press: January 8, 2024
Published online: February 18, 2024
ARTICLE HIGHLIGHTS
Research background

Anatomical shoulder arthroplasties used for glenohumeral osteoarthritis are often evaluated by mean improvement in patient reported outcome measurements. However, these mean improvements do not talk much about how the individual patient is performing. Therefore, we have aimed to focus on each individual patient’s improvement. These improvements are linked to the minimal clinical important difference, allowing us to determine the proportion of patients achieving a clinically relevant improvement.

Research motivation

To determine the proportion of patients with glenohumeral osteoarthritis and treated with an anatomical shoulder arthroplasty that achieve a clinically relevant improvement. This a new way of analyzing the results which is much more relevant to the individual patient.

Research objectives

To determine the proportion of patients having a clinically relevant improvement two years postoperatively after treatment with an anatomical total shoulder arthroplasty. In future research, we believe that this will be a frequently used analysis method.

Research methods

We used data from three different patient reported outcome measurements. The improvements from preoperatively to two years postoperatively were connected to the associated minimal clinically important difference (MCID). The proportion of patients exceeding the MCID was defined as the rate of clinically relevant improvement.

Research results

The rate of clinically relevant improvement was 87%, 94%, and 88% for the three different patient reported outcome measurements.

Research conclusions

Using a new method for analysis of improvements in patient reported outcome measurements, we found that approximately 90% of patients with glenohumeral osteoarthritis and treated with an anatomical shoulder arthroplasty achieved a clinically relevant improvement.

Research perspectives

In future research, this method will probably be a frequently used analysis method. The results of this study should be confirmed in larger cohorts.