Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. May 18, 2023; 14(5): 340-347
Published online May 18, 2023. doi: 10.5312/wjo.v14.i5.340
Spinal fusion is an aerosol generating procedure
Joanna Lind Langner, Nicole Segovia Pham, Ann Richey, Yousi Oquendo, Shayna Mehta, John Schoeneman Vorhies
Joanna Lind Langner, Nicole Segovia Pham, Ann Richey, Shayna Mehta, John Schoeneman Vorhies, Pediatric Orthopaedic Surgery, Stanford University, Palo Alto, CA 94304, United States
Yousi Oquendo, Orthopaedic Surgery, Hospital for Special Surgery, New York, NY 10021, United States
Author contributions: All authors contributed to the study conception and design; Langner JL, Pham NS, Richey A, Oquendo Y, Mehta S, and Vorhies JS performed material preparation, data collection, and analysis; the first draft of the manuscript was mainly written by Langner JL and Vorhies JS and all authors assisted on previous versions of the manuscript; all authors read and approved the final manuscript.
Institutional review board statement: Approval was granted an institutional review board statement waiver by the Ethics Committee of Stanford University (No. 58206).
Informed consent statement: The informed consent was waived from the patients.
Conflict-of-interest statement: Dr. John Vorhies receives grant funding from the Scoliosis Research Society (SRS), Pediatric Orthopaedic Surgery of North America (POSNA), and Stanford University. Dr. John Vorhies is a consultant for Ortho Pediatrics and Nview Medical, and a committee member of the SRS Research Grant Committee and POSNA’s Industry Relations Committee and Research Committee, and a former member of the POSNA Evidence-Based Practice committee. The other authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this manuscript. The author(s) received no financial support for the research, authorship, and/or publication of this article.
Data sharing statement: No additional data is available for sharing.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: John Schoeneman Vorhies, MD, Assistant Professor, Pediatric Orthopaedic Surgery, Stanford University, 453 Quarry Road, 3rd Floor, MC 5658, Palo Alto, CA 94304, United States. john.vorhies@stanford.edu
Received: January 23, 2023
Peer-review started: January 23, 2023
First decision: January 31, 2023
Revised: February 14, 2023
Accepted: March 27, 2023
Article in press: March 27, 2023
Published online: May 18, 2023
Processing time: 115 Days and 13.3 Hours
ARTICLE HIGHLIGHTS
Research background

The coronavirus disease 2019 (COVID-19) pandemic has raised awareness of aerosol generation during medical procedures as an occupational hazard. Several authors have speculated that certain steps during spinal fusion have the potential to generate aerosols, however there is a dearth of data to quantify this risk. Publishing the type of data, we present here is critical to help hospitals create evidence-based workplace safety policies. As such, we believe that the findings presented here will be of interest to the readership of your journal and will hopefully inform future research and clinical care.

Research motivation

Several steps in spinal fusion are associated with increased airborne particle counts in the aerosol size range. Further research is warranted to determine if such particles have the potential to contain infectious viruses.

Research objectives

Upon univariate analysis, bovie (P < 0.0001), high speed pneumatic burring (P = 0.009), and ultrasonic bone scalpel (P = 0.002) were associated with increased 0.3-0.5 μm/m3 particle counts relative to baseline. Bovie (P < 0.0001) and burring (P < 0.0001) were also associated with increased 1-5 μm/m3 and 10 μm/m3 particle counts. Our logistic regression model demonstrated that bovie (OR = 10.2, P < 0.001), burring (OR = 10.9, P < 0.001), and bone scalpel (OR = 5.9, P < 0.001) had higher odds of a spike in 0.3-0.5 μm/m3 particle counts. Bovie (OR = 2.6, P < 0.001), burring (OR = 5.8, P < 0.001), and bone scalpel (OR = 4.3, P = 0.005) had higher odds of a spike in 1-5 μm/m3 particle counts.

Research methods

We quantified airborne particle counts during five posterior spinal instrumentation and fusions (9/22/2020-10/15/2020) using an optical particle sizer (OPS) near the surgical field. Data were analyzed by 3 particle size groups: 0.3-0.5 μm/m3, 1.0-5.0 μm/m3, and 10.0 μm/m3. We used hierarchical logistic regression to model the odds of a spike in aerosolized particle counts based on the step in progress.

Research results

In this study we use a handheld OPS to measure the generation of aerosols during surgical steps in spinal fusion because of the risk this may confer upon surgeons in regards to the airborne transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Research conclusions

Several steps in spinal fusion may aerosolize blood but little data exists to quantify the risk this may confer upon surgeons.

Research perspectives

Transmission of SARS-CoV-2 can occur during aerosol generating procedures. Several steps in spinal fusion may aerosolize blood but little data exists to quantify the risk this may confer upon surgeons.