Published online Oct 18, 2019. doi: 10.5312/wjo.v10.i10.348
Peer-review started: May 20, 2019
First decision: July 31, 2019
Revised: August 14, 2019
Accepted: September 4, 2019
Article in press: September 4, 2019
Published online: October 18, 2019
Processing time: 158 Days and 0.6 Hours
Coagulase-negative Staphylococci (CoNS) are difficult-to-treat microorganisms in periprosthetic joint infections (PJIs) of the hip and knee. The resistance of these bacteria to antibiotics is increasing.
To date, no infection eradication rates of treatment for this type of specific infection have been reported.
To evaluate the infection eradication rate of two-stage revision arthroplasty for CoNS PJI of the hip and knee.
Retrospective cohort study of all patients treated with two-stage revision for CoNS PJI of a hip or knee prosthesis.
In 33 of 44 patients, the infections were eradicated at a mean of 37 mo after two-stage revision surgery of the hip and knee.
Two-stage revision surgery of the hip and knee for PJI infections with CoNS leads to infection eradication rate comparable to other causative pathogens.
Two-stage revision yields an acceptable infection eradication rate for treatment of CoNS infection of the hip and knee. Future studies should consider combining cohorts of patients from multiple centres to achieve larger cohorts of patients.