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Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. Jul 18, 2022; 13(7): 622-630
Published online Jul 18, 2022. doi: 10.5312/wjo.v13.i7.622
Septic arthritis of the hand: Current issues of etiology, pathogenesis, diagnosis, treatment
Konstantin V Lipatov, Arthur Asatryan, George Melkonyan, Aleksandr D Kazantcev, Ekaterina I Solov’eva, Urii E Cherkasov
Konstantin V Lipatov, Aleksandr D Kazantcev, Department of General Surgery, Institute of Clinical Medicine named after N.V. Sklifosovsky, Sechenov First Moscow State Medical University (Sechenov University), Moscow 119021, Russia
Arthur Asatryan, Wound and Wound Infection Surgery, State Budgetary Institution “City Clinical Hospital named after S.S. Yudin of Moscow Healthcare Department”, Moscow 115446, Russia
George Melkonyan, Department of General Surgery, Physician of The Hospital for War Veterans No 3, Moscow 129336, Russia
Ekaterina I Solov’eva, Urii E Cherkasov, Department of General Surgery, I.M. Sechenov First Moscow State Medical University, Moscow 119048, Russia
Author contributions: Lipatov V Konstantin performed conceptualization, writing - review & editing; Asatryan Arthur and Melkonyan George performed methodology, writing - original draft; Kazantcev D Aleksandr performed visualization, writing - review & editing; Solov’eva I Ekaterina and Cherkasov E Urii performed investigation; supervision.
Conflict-of-interest statement: All the authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Konstantin V Lipatov, Doctor, MD, Doctor, Full Professor, Department of General Surgery, Institute of Clinical Medicine named after N.V. Sklifosovsky, Sechenov First Moscow State Medical University (Sechenov University), Rossolimo street, 11-2, Moscow 119021, Russia. lipatov_k_v@staff.sechenov.ru
Received: March 27, 2022
Peer-review started: March 27, 2022
First decision: June 16, 2022
Revised: June 19, 2022
Accepted: July 8, 2022
Article in press: July 8, 2022
Published online: July 18, 2022
Processing time: 112 Days and 7.1 Hours
Abstract

Septic arthritis of the hand is a serious disease that often results in dysfunction of the joint or even the need to perform amputation of the finger. They rank second in the frequency of occurrence after lesions of the knee joint. Many points concerning the etiology, the timing of the development of cartilage destruction and the development of osteomyelitis, approaches to surgical treatment, the duration of antibiotic therapy, and the start of rehabilitation measures remain the subject of numerous discussions. Based on a search in the PubMed, Web of Science and Google Scholar databases down to 1990-2021, publications on septic arthritis of the hand were found and analyzed. The following inclusion criteria were used in our review: (1) Septic arthritis of the hand; (2) Published in a peer review journal; (3) Written in English; and (4) Full text version available. Studies were excluded if they met any of the following criteria: (1) Letters; (2) Articles published in abstract form only; and (3) Cadaveric studies. Septic arthritis of the hand was characterized by the most frequent damage to the joints of the index and middle fingers (> 50% of cases). Up to 90% of cases, the infection enters the joint as a result of penetrating trauma, animal bites, etc. Staphylococcus aureus became the most frequently isolated microorganism (30%-55%), and its polyantibiotic-resistant form Methicillin-resistant Staphylococcus aureus was found, according to various sources, from 0% to 73% among all isolated Staphylococcus aureus. In arthritis, Pasteurella multocida (6%-11%) is often isolated as a result of animal bites. Articular cartilage destruction in the experiment developed within 24-48 h after infection. In clinical studies, the development of osteomyelitis was noted when treatment was delayed by more than 10 d. X-ray data during the first two weeks were uninformative. Priority of surgical treatment of septic arthritis. Drainage and surgical treatment, and with the development of osteomyelitis, the implementation of arthrodesis. Antibacterial therapy for 2-4 wk and early start of rehabilitation measures. Timely surgical treatment in combination with antibiotic therapy and rehabilitation makes it possible to obtain a positive result in the treatment of septic arthritis of the hand.

Keywords: Septic arthritis; Hand; Staphylococcus aureus; Metacarpophalangeal joint; Interphalangeal joint; Rehabilitation

Core Tip: Septic arthritis of the hand often occurs as a result of penetrating wounds. The most common causative agent is Staphylococcus aureus, often characterized by high antibiotic resistance. Delayed treatment of septic arthritis can lead to cartilage destruction and osteomyelitis. To achieve a positive result in the treatment of septic arthritis of the hand, timely surgery, adequate antibiotic therapy and early rehabilitation are necessary.