Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Orthop. May 18, 2022; 13(5): 454-464
Published online May 18, 2022. doi: 10.5312/wjo.v13.i5.454
Distal femur complex fractures in elderly patients treated with megaprosthesis: Results in a case series of 11 patients
Fabio Zanchini, Antonio Piscopo, Valerio Cipolloni, Federico Fusini, Stefano Cacciapuoti, Davide Piscopo, Charlotte Pripp, Luigi Aurelio Nasto, Enrico Pola
Fabio Zanchini, Davide Piscopo, Luigi Aurelio Nasto, Enrico Pola, Orthopaedics and Traumatology Division, Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli" School of Medicine, Naples 80138, Italy
Antonio Piscopo, Stefano Cacciapuoti, Department of Orthopedics and Traumatology, Sacro Cuore di Gesù Fatebenefratelli Hospital, Benevento 82100, Italy
Valerio Cipolloni, Spine Division, Department of Orthopaedics and Traumatology, A. Gemelli IRCCS University Hospital, Catholic University of Rome, Rome 00168, Italy
Federico Fusini, Department of Orthopaedic and Traumatology, Regina Montis Regalis Hospital, Mondovì 12084, Italy
Charlotte Pripp, Service de Geriatrie et réaaptation HUG, Hôpital de Bellerive Chem, Genève 1205, Switzerland
Author contributions: Pola E and Zanchini F participated in the conceptualization; Piscopo A participated in surgical technique development; Cipolloni V and Nasto LA participated in methodology and writing-original preparation; Pola E participated in validation; Cipolloni V and Piscopo D participated in formal analysis and investigation; Cipolloni V and Pripp C participated in data curation; Nasto LA participated in writing–review and editing; Pola E, Piscopo A and Cacciapuoti S participated in supervision; All authors have read and agreed to the published version of the manuscript.
Institutional review board statement: The study was conducted according to the guidelines of the Declaration of Helsinki and approved by the Institutional Review Board of our Institution.
Informed consent statement: The informed consent statement was waived.
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: Data will be made available upon request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Enrico Pola, PhD, Professor, Orthopaedics and Traumatology Division, Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli" School of Medicine, Via del Sole 10, Naples 80138, Italy. enrico.pola@unicampania.it
Received: December 29, 2021
Peer-review started: December 29, 2021
First decision: February 21, 2022
Revised: March 19, 2022
Accepted: April 27, 2022
Article in press: April 27, 2022
Published online: May 18, 2022
Abstract
BACKGROUND

Surgical treatment of complex fractures of the distal femur in the elderly is controversial. Osteoporosis and pre-existent osteoarthritis are common comorbidities in the elderly which add to the need for early walking and rapid restoration of function and also pose significant obstacles to achievement of satisfactory results with standard fixation techniques. Recently, several authors have suggested that primary arthroplasty could be a viable alternative option to standard fixation techniques in selected patients with complex distal femur fractures.

AIM

To present our experience with 11 cases of distal femur fractures treated with knee arthroplasty and large femoral resection in a population of patients over the age of 85.

METHODS

Data from 11 consecutive patients (10 females, 1 male) presenting with acute intra-articular supracondylar or intercondylar distal femur fractures and with pre-existent primary osteoarthritis who were treated with primary knee arthroplasty were recorded. We collected standard demographic data, comorbidities and patient reported outcomes including Visual Analogical Scale (VAS), Oxford Knee Score (OKS) and Barthel’s Index. Post-operative joint range of motion (ROM) and standard radiographic data were also collected.

RESULTS

At a mean follow-up of 23.2 mo, all of the implants were well-positioned and osteointegrated. Furthermore, all the patients were alive and walking either independently or with walking aids. There was a marked improvement in pain (VAS 4.5 postop vs 1.9 at the last follow-up), OKS score (29.5 postop vs 36.81 at the last follow-up), ROM (96.2° postop vs 102° at the last follow-up) and restoration of pre-injury ambulatory status (average Barthel Index 77.3). The radiographic evaluations showed good restoration of the articular geometry. No deaths and no complications were recorded.

CONCLUSION

In conclusion, we believe that knee megaprosthesis in the case of complex fractures of the distal femur is a valid surgical choice. This is particularly true in elderly patients with severe osteoporosis and pre-existing osteoarthritis. It is important to note that this surgery should be performed by surgeons with proven experience in prosthetic hip and knee surgery and that a scrupulous selection of the cases is completed.

Keywords: Knee, Joint replacement, Megaprosthesis, Elderly, Distal femur fracture

Core Tip: We evaluated safety and efficacy of a knee megaprosthesis in the setting of complex fractures of the distal femur in elderly patients with a short-term follow-up. We retrospectively evaluated 11 patients over the age of 85 treated with distal femoral replacement with a fully porous coated metaphyseal sleeve for acute fractures of the distal femur with a minimum follow-up of 2 years. During our study period we observed stability of the implants and improvement in the Visual Analogical Scale, Oxford Knee Score, range of motion, Barthel Index, quality of life and survival.