Oxaliplatin-induced diffuse alveolar hemorrhage: A case report

Table 1 Previously reported cases of oxaliplatin-induced diffuse alveolar hemorrhage

Characteristics	Kumaran et al[6]	Lou et al[5]	Watkins et al[2]	Present case
Types of cancer	Unknown primary	Esophageal	Colorectal	Esophageal
Regimen	Oxaliplatin	FOLFOX	FOLFOX	FOLFOX and S-1
Chemotherapy before onset	1 cycle	1 cycle	11 cycles	8 cycles
Mechanical ventilation	Yes	Yes	Yes	Yes
Treatment	Corticosteroids	mPSL 1 mg/kg	mPSL 125 mg q6h	mPSL 1000 mg
Timing of corticosteroids	Not addressed	Not addressed	After 3 days of hospitalization	On the day of hospitalization
Outcome	Extubation	Extubation	Death	Extubation

FOLFOX: Folinic acid, fluorouracil, and oxaliplatin; mPSL: Methylprednisolone; S-1: Started oral fluoropyrimidine; q6h: Every 6 hours.