Epidemiologic risk factors for patients admitted with chronic pancreatitis and pancreatic ductal adenocarcinoma in the United States

Table 1 Demographics, ethno-racial, socioeconomic, and hospital factors for patients hospitalized with chronic pancreatitis

Variable	n = 371275
Race
White	64.82%
Black	22.35%
Hispanic	8.4%
Asian or Pacific Islander	1.31%
Native American	0.87%
Other	2.25%
Gender
Women	44.24%
Men	55.76%
Age
Mean age, years	52.72
Age 18-39 yr	21.63%
Age 40-59 yr	49.84%
Age 60-79 yr	24.26%
Age > 80 yr	4.28%
Insurance provider
Medicare	40.2%
Medicaid	30.28%
Private	22.53%
Uninsured	6.99%
Charlson comorbidity index
0	24.09%
1	25.97%
2	17.37%
3 or more	32.58%
Median income in patient zip code
$1–$38999	36.17%
$39000–$47999	26.11%
$48000–$62999	21.78%
$63000	15.94%
Hospital region
Northwest	17.54%
Midwest	24.63%
South	40.23%
West	17.6%
Hospital location
Rural	8.29%
Urban	91.71%
Hospital size
Small	19%
Medium	28.34%
Large	52.65%
Type of hospital
Teaching	69.54%
Non-teaching	30.46%

Table 2 Multivariate regressions analysis for demographic, socioeconomic, and hospital factors associated with hospitalizations secondary to chronic pancreatitis

Classification		P value
Age	aOR 0.98	< 0.01
Age 18-39 yr	Reference
Age 40-59 yr	aOR 2.60	< 0.01
Age 60-79 yr	aOR 0.96	0.37
Age > 80 yr	aOR 0.46	< 0.01
BMI: 18-24.9	Reference
BMI: 25-29.9	aOR 1.34	< 0.01
BMI: 30-39.9	aOR 0.62	< 0.01
Women	aOR 0.65	< 0.01
Whites	Reference
Blacks	1.13	< 0.01
Hispanics	0.63	< 0.01
Asians/Pacific Islanders	0.50	< 0.01
Native Americans	1.05	0.31
Other	0.67	< 0.01

aOR: Adjusted odds ratio; BMI: Body mass index.

Table 3 Demographics, ethno-racial, socioeconomic, and hospital factors for patients hospitalized with chronic pancreatitis and pancreatic ductal adenocarcinoma

Variable	CP without PDAC (n = 368385)	CP with PDAC (n = 2890)	P value
Race			< 0.01
Whites	64.75%	74.22%
Blacks	22.4%	16.76%
Hispanics	8.43%	4.97%
Asians or Pacific Islanders	1.31%	1.29%
Native Americans	0.87%	0.37%
Other	2.25%	2.39%
Gender
Women	44.27%	40.31%	0.07
Men	55.73%	59.69%
Age
Mean age, years	52.61	66.32	< 0.05
Age 18-39 yr	21.78%	19%
Age 40-59 yr	50.02%	26.99%
Age 60-79 yr	23.97%	60.03%
Age > 80 yr	4.23%	11.07%
Insurance provider			< 0.01
Medicare	40.04%	60.64%
Medicaid	30.44%	10.73%
Private	22.5%	26.48%
Uninsured	7.03%	2.15%
Charlson comorbidity index			< 0.01
0	24.28%	0
1	26.17%	0
2	17.35%	19.38%
3 or more	32.2%	80.62%
Median income in patient zip code			< 0.01
$1–$38999	36.24%	28.22%
$39000–$47999	26.1%	26.81%
$48000–$62999	21.78%	21.34%
$63000	15.88%	23.63%
Hospital region			0.68
Northwest	17.53%	19.38%
Midwest	24.64%	23.53%
South	40.25%	38.24%
West	17.59%	18.86%
Hospital location			< 0.01
Rural	8.34%	1.56%
Urban	91.66%	98.44%
Hospital size			< 0.01
Small	19.08%	8.65%
Medium	28.43%	16.78%
Large	52.48%	74.57%
Type of hospital
Teaching	69.41%	86.16%	< 0.01
Non-teaching	30.59%	13.84%

CP: Chronic pancreatitis; PDAC: Pancreatic ductal adenocarcinoma.

Table 4 Multivariate regressions analysis for demographic, socioeconomic, and hospital factors associated with hospitalizations in patients with chronic pancreatitis and pancreatic ductal adenocarcinoma

Classification		P value
Age	aOR 1.05	< 0.01
Age 18-39 yr	Reference
Age 40-59 yr	aOR 6.79	< 0.01
Age 60-79 yr	aOR 24.17	< 0.01
Age > 80 yr	aOR 21.02	< 0.01
BMI: 18-24.9	Reference
BMI: 25-29.9	aOR 2.40	< 0.01
Female	aOR 0.77	< 0.01
White	Reference
Black	aOR 0.77	< 0.05
Hispanic	aOR 0.66	< 0.05
Asian or Pacific Islander	aOR 0.69	0.36
Native American	aOR 0.68	0.60
Other	aOR 0.97	0.94

aOR: Adjusted odds ratio; BMI: Body mass index.