Mapping the landscape of gastric signet ring cell carcinoma: Overcoming hurdles and charting new paths for advancement

Figure 1 Flowchart of article selection.

Figure 2 Annual growth trend of publications on gastric signet ring cell carcinoma from January 1, 2004 to January 31, 2024.

Figure 3 National collaborative network for publications related to gastric signet ring cell carcinoma. Countries are represented by nodes. Partnerships are represented by lines. The node area expands as the number of publications increases. China has close cooperation with countries such as South Korea, France, and Canada, whereas Japan has even closer collaborations with the United States, Germany, Italy, and other countries.

Figure 4 Visualization of journals related to gastric signet ring cell. A: Network visualization of co-cited journals. The size of the circle indicates the number of co-citations. The journals most frequently co-cited are Gastric Cancer, followed closely by Cancer and World Journal of Gastroenterology; B: A dual-map overlay presents journals related to gastric signet ring cell carcinoma with citing journals displayed on the left and cited journals on the right. The colored paths between them illustrate the citation relationships. Research published in molecular/biology/immunology journals is predominantly cited by journals in the molecular/biology/genetics field, while research published in medicine/medical/clinical is mainly cited by journals in the molecular/biology/genetics as well as health/nursing/medicine fields.

Figure 5 Visualization of co-cited references related to gastric signet ring cell carcinoma. A: Knowledge map of co-cited references. Different colors represent distinct clusters; B: Timeline view of co-cited references related to GSRCC. “Prophylactic gastrectomy”, “syndecan-1”, “tubular adenocarcinoma”, as well as “NADPH oxidase 1” are among the early research hotspots. “Signet ring cell”, “FDG-PET”, “recurrence”, “diffuse”, “CDH1”, and “colorectum” are considered as mid-term research hot topics. “Poorly cohesive”, “lobular breast cancer”, and “gastrectomy” currently represent the hot topics and trends in this field.

Figure 6 The keyword clustering volcano plot visually demonstrates how research hotspots evolve and shift over time.