Impact of conditioning regimen on peripheral blood hematopoietic cell transplant

Figure 1 Cumulative incidence of acute GvHD by total nucleated cell dose in myeloablative + total body irradiation conditioning. A: Higher total nucleated cell dose had a higher incidence of acute GvHD grade II-IV; B: Total nucleated cell dose is not associated with acute GvHD grade III-IV; C: CD34+ cell dose is not associated with acute GvHD grade II-IV; D: Lower CD34+ cell dose has a higher incidence of acute GvHD grade III-IV. GvHD: Graft-versus-host disease.

Figure 2 OS by total nucleated cell dose. A: OS was not significantly different in patients conditioned without TBI; B: OS was significantly better with a higher total nucleated cell dose in patients conditioned with TBI; C: OS was not significantly different in patients conditioned with myeloablative TBI; D: OS was significantly better with a higher total nucleated cell dose in patients conditioned with reduced intensity TBI. OS: Overall survival; TBI: Total body irradiation.