Main controversies in breast cancer

Core Tip

Core tip: Taking into consideration the progress in diagnosis and treatment in the female breast cancer, it is inevitable that some controversies will come up in daily clinical practice. The aim of this review is to illustrate some of these conflicting issues and make them less “ambiguous”. Thus, this has been achieved in the issues of mammography, magnetic resonance imaging, fine needle aspiration and core biopsy, axillary dissection, internal mammary node sampling, accelerated partial breast irradiation, the sequence of chemoradiotherapy, negative margin width, while controversial are still remain the themes of tomosynthesis, 3D ultrasound, shear wave elastography, positron emission tomography-computed tomography (PET-CT), CT-scan and bone scintigraphy, hormonotherapy, bisphosphonates and sentinel lymph node biopsy.